ZURZUVAE

Indicated For

Postpartum Depression, Major Depressive Disorder

About This Medication

# ZURZUVAE Patient Guide: How to Get ZURZUVAE at Low or No Cost ZURZUVAE (zuranolone) is the first FDA-approved oral medication specifically for postpartum depression (PPD) in adults, offering a 14-day treatment course that can improve symptoms as early as Day 3.[5][7] Sage Therapeutics provides the **ZURZUVAE Savings Card Program** and patient support through **ZURZUVAE For You** and **Sage Central** to help eligible patients access it at $0 out-of-pocket, even if uninsured or underinsured.[1][2][3] ## About ZURZUVAE and Postpartum Depression **Postpartum depression (PPD)** affects many new mothers, causing persistent sadness, anxiety, and difficulty bonding with your baby that can last weeks or months.[5] Traditional antidepressants often take 6-8 weeks to work, but **ZURZUVAE** is taken as capsules twice daily for just 14 days, acting faster with a novel mechanism targeting brain chemicals like GABA.[4][6] The list price is $15,900 for the full course, but support programs make it affordable for most.[7] ZURZUVAE is dispensed only through a limited network of specialty pharmacies, requiring a prescription from your healthcare provider (HCP).[1][8] It's covered by about 95% of commercial insurance and Medicaid plans, plus major pharmacy benefit managers.[7] ## Who Qualifies for Financial Assistance? Sage Therapeutics' programs focus on **commercial insurance** holders, uninsured, and underinsured patients rather than strict income limits.[1][2][3] The **ZURZUVAE Savings Card Program** lets **eligible commercially insured adults pay as little as $0 copay** per prescription, applied directly at the specialty pharmacy.[1][2][7] Uninsured or functionally uninsured patients also qualify for $0 out-of-pocket via copay assistance.[3][4] | Eligibility Category | Details | Examples/Notes | |----------------------|---------|---------------| | **Commercial Insurance** | Savings Card reduces copay to $0 for eligible patients. Restrictions apply; check terms.[1][2] | Most common; covers ~95% of plans.[7] | | **Uninsured/Underinsured** | Copay assistance covers full cost ($0 OOP).[3][4] | Includes high-coinsurance situations. | | **Medicaid** | Often covered; assistance may supplement. Contact Sage Central.[7] | Varies by state. | | **Medicare** | Not explicitly detailed; prior authorization likely needed. Call Sage Central for options.[1][8] | May have limitations. | | **Income-Based** | No specific FPL thresholds listed; program emphasizes insurance status over income.[2][3] | States like CA cap copays at $250.[3] | **Key**: Always verify with your HCP and Sage support, as eligibility depends on plan specifics and program rules.[2] ## Insurance Requirements ZURZUVAE often requires **prior authorization (PA)** from your insurer, where your HCP submits medical history, PPD diagnosis, and prior treatments.[1][8] Use CoverMyMeds or your plan's form, including chart notes and demographics.[1] Sage's specialty pharmacy network can initiate PAs to speed things up.[8] - **Commercial/Medicaid**: High coverage rates; savings card for copays.[7] - **No insurance?** Direct assistance available.[3] - Provide pharmacy/medical insurance info to start.[1] ## Step-by-Step Application Process 1. **Get Prescribed**: Discuss PPD symptoms with your HCP. They confirm diagnosis and prescribe ZURZUVAE.[5] 2. **Send Prescription**: HCP sends Rx, insurance details, and demographics to a ZURZUVAE network specialty pharmacy. Verify options with your plan.[1] 3. **Handle Prior Authorization**: HCP or pharmacy submits PA with supporting docs (e.g., PPD notes, prior treatments).[1][8] Monitor via ePA platforms like CoverMyMeds.[8] 4. **Apply for Savings Card**: Visit zurzuvae.com or call Sage Central (1-844-472-4379, Mon-Fri 8AM-6PM ET) for the ZURZUVAE Savings Card if commercially insured. Uninsured? Request copay assistance.[2][4] 5. **Enroll in ZURZUVAE For You**: Free support program with coordinators for financial help, insurance navigation, and resources. Hablamos español.[2][5] 6. **Pharmacy Fills**: Specialty pharmacy applies assistance directly; you pick up at $0 if eligible.[2] Contact **Sage Central** early for case managers to assist.[4] ## Timeline and Delivery - **PA Processing**: Varies by insurer; network pharmacies help minimize delays. Some report easy access shortly after launch.[1][4][8] - **Total Time**: Days to weeks, depending on PA. Support coordinators track status.[2] - **Delivery**: Shipped to/home delivery via specialty pharmacy or pickup. 14-day supply once approved.[1][7] Support available Mon-Fri 8AM-6PM ET.[2] ## Alternatives if Denied or Ineligible - **Appeal**: Sage Central and groups like Policy Center for Maternal Mental Health help with appeals.[3][4] - **Other Treatments**: Therapy, standard antidepressants (slower onset), or brexanolone (Zulresso, IV, $34K, hospital stay).[6] - **State Caps**: E.g., CA limits copays to $250.[3] - **GoodRx/Discounts**: Check for additional savings, though manufacturer program is primary.[7] ## Important Disclaimer This guide is for informational purposes only and not medical/financial advice. Eligibility, coverage, and costs vary; consult your HCP, insurer, and Sage Therapeutics. Program terms/restrictions apply; see official sites. ZURZUVAE has a Boxed Warning—discuss risks with your doctor. Data as of latest available (2023-2024).[1][8] (Word count: 942)

Program information last verified: March 30, 2026