Zurampic

Indicated For

hyperuricemia associated with gout

About This Medication

# Zurampic (lesinurad) Patient Guide: How to Get Zurampic at Low or No Cost **Important Notice: Zurampic (lesinurad) is no longer available.** Ironwood Pharmaceuticals discontinued sales of Zurampic and related patient assistance programs in February 2019.[8] This guide provides historical context and alternatives for managing gout-related hyperuricemia. ## About Zurampic (lesinurad) Zurampic was an FDA-approved oral tablet used **in combination with a xanthine oxidase inhibitor (XOI)**, such as allopurinol or febuxostat, to treat **hyperuricemia associated with gout** in adults who did not achieve target serum uric acid (sUA) levels with an XOI alone.[3][5] It works by inhibiting URAT1 and OAT4 transporters in the kidneys, reducing uric acid reabsorption and increasing its excretion.[5][6] **Key limitations:** Zurampic was **not for asymptomatic hyperuricemia** or as monotherapy due to risks like acute renal failure, which occurred more often when used alone.[3][5] Common side effects included headache, influenza, increased blood creatinine, and gastroesophageal reflux.[3] It was a once-daily tablet, typically showing sUA reductions within one month when added to XOI therapy.[3] Since discontinuation, patients should consult their doctor for alternative treatments like other uricosurics (e.g., probenecid) or XOIs.[8] ## Who Qualifies for Assistance? No official manufacturer patient assistance program (PAP) details are available from Ironwood Pharmaceuticals, as the drug and its programs ended in 2019.[8] Historically, third-party services like Prescription Hope offered Zurampic for a flat **$70 per month**, regardless of income, for pre-qualified patients.[1] RxAssist listed a program but provided no specific eligibility criteria, such as income thresholds or residency requirements.[2] **General PAP qualifications** (based on similar programs): - U.S. residents (citizens or legal). - Uninsured, underinsured, or facing high copays. - Prescription from a licensed physician. Since no active Ironwood program exists, explore generic lesinurad (if available) or alternatives via other PAPs.[8] ## Income Eligibility Breakdown Specific income thresholds for Zurampic's program are unavailable.[2] Prescription Hope charged a flat fee without FPL-based limits.[1] For reference, typical PAPs use **400-500% of the Federal Poverty Level (FPL)**. Use the [Federal Poverty Level Calculator](https://aspe.hhs.gov/topics/poverty-economic-mobility/poverty-guidelines) for current figures. | Household Size | 400% FPL (2026 est.) | 500% FPL (2026 est.) | Notes | |---------------|----------------------|----------------------|-------| | Individual | ~$60,000 | ~$75,000 | Estimates; actual varied. | | Couple | ~$81,000 | ~$101,000 | Deductions for medical expenses common. | | Family of 3 | ~$102,000 | ~$127,000 | Check third-party programs. | | Family of 4 | ~$123,000 | ~$154,000 | N/A for Zurampic.[2] | **Notes:** No deductions or Social Security specifics listed.[2] Always verify with current providers. ## Insurance Requirements Details unavailable.[2] Generally, PAPs require patients to be uninsured or have Medicare Part D/insurance that doesn't cover the drug fully. Zurampic was often for those failing XOI monotherapy, so prior authorization was likely needed.[3] Medicare patients could explore Extra Help; contact 1-800-MEDICARE. ## Step-by-Step Application Process **No active program exists.**[8] Previously: 1. **Consult your doctor:** Get a prescription confirming need for Zurampic + XOI.[3] 2. **Check third-party options:** Enroll via Prescription Hope for $70/month (pre-2019).[1] 3. **Gather documents:** Proof of income, residency, prescription, insurance denial (if applicable).[2] 4. **Apply online/phone:** Use sites like rxassist.org or prescriptionhope.com.[1][2] 5. **Physician completes form:** Include license and signature.[2] 6. **Submit via fax/mail:** Wait for approval letter.[2] For alternatives, visit NeedyMeds.org or Partnership for Prescription Assistance. ## Timeline and Delivery Processing time, quantity, and shipping details not specified.[2] Third-party programs like Prescription Hope aimed for quick pre-qualification and monthly delivery.[1] Expect 2-4 weeks historically; refills automatic until ineligible. ## Alternatives if Denied or Unavailable - **Switch medications:** Allopurinol, febuxostat, probenecid, or pegloticase (KRYSTEXXA PAP available).[3] - **Third-party hubs:** RxHope, Patient Access Network (PAN), or HealthWell Foundation for gout drugs. - **Generic options:** Check for lesinurad generics (post-patent). - **Discount cards:** GoodRx, SingleCare for cash-pay savings. - **Clinical trials:** Search ClinicalTrials.gov for gout studies. Contact Ironwood at their patient resources page for guidance.[7] ## Disclaimer This guide is for informational purposes only and not medical advice. Zurampic is discontinued; consult your healthcare provider before changing treatments.[8] Program details based on historical data and may be outdated.[1][2] Eligibility, costs, and availability change; verify directly. Ironwood Pharmaceuticals and affiliates disclaim liability. Word count: 912.

Program information last verified: March 25, 2026