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Cardiology

Zontivity

Generic: vorapaxar

Manufacturer: Merck Sharp & Dohme Corp.  ·  Program: Merck Patient Assistance Program

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Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Uninsured or no prescription drug coverage

Residency

US resident

Income Threshold

Up to 400% FPL

Individual Income Limit

$58,320/year

Must be uninsured or have inadequate coverage

Program Information

Processing Time

2–3 weeks

Delivery Method

shipped to patient or physician office

Application Method

Multiple

Reauthorization

Required, annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • proof of income
  • proof of residency
  • prescription

Indicated for

myocardial infarction, peripheral arterial disease

About This Medication

Merck Patient Assistance Program Patient Guide: How to Get Zontivity (vorapaxar) at Low or No Cost

Zontivity (vorapaxar) is a prescription medication used to reduce the risk of heart attack, stroke, or certain types of blood vessel disease in patients with a history of heart issues who are also taking aspirin and/or clopidogrel. The Merck Patient Assistance Program (PAP) offers this medication at no cost to eligible uninsured or underinsured U.S. residents who meet income and other criteria.[1][2][8]

About Zontivity (vorapaxar)

Zontivity is an antiplatelet drug that helps prevent blood clots from forming in people with peripheral artery disease (PAD) or a history of heart attack or stroke. It works by blocking a protein called PAR-1 on platelets, reducing the chance of clot-related events. It's typically taken as one 2.08 mg tablet daily, alongside aspirin and/or clopidogrel (Plavix), but only under a doctor's close supervision due to risks like bleeding. Common side effects include bleeding (e.g., nosebleeds, bruising), anemia, and high blood pressure. Always follow your doctor's instructions and report unusual bleeding immediately. This program provides free Zontivity through Merck Sharp & Dohme Corp. for those who qualify.[1][7]

Who Qualifies for the Program?

To join the Merck PAP, you must meet all these key requirements:

  • Reside in the U.S. or U.S. territory (no citizenship required).[1][3][5]
  • Have a valid prescription for Zontivity from a U.S.-licensed healthcare provider.[1][8]
  • Be uninsured or lack prescription drug coverage for this medication. No government or employer insurance that requires PAP participation.[1][5]
  • Meet financial eligibility based on household income (specific Federal Poverty Level (FPL) thresholds not publicly detailed; program verifies electronically or via documents).[1][4][8]

The program targets those in financial need who can't afford their meds. It's not for patients with active prescription coverage.[2][4]

Income Eligibility Breakdown

Merck PAP bases eligibility on household income, but exact FPL percentages (e.g., 400%, 500%) aren't specified in public sources—check merckhelps.com or call 800-727-5400 for your situation.[1][4] They often verify electronically via credit report (no impact on your score) or accept proof like tax returns.[1][8] Here's a general guide based on typical PAP structures (confirm with Merck):

Household SizeEstimated Max Annual Income (300-500% FPL)*Notes
1 person$45,000 - $75,000Varies; electronic verification preferred [1][4]
2 people$60,000 - $100,000Household income only [8]
3 people$75,000 - $125,000Includes all residents [1]
4 people$90,000 - $150,000Add ~$15K per extra person*

*Estimates for illustration; actual thresholds may differ. Program may limit to calendar year.[6][8] Uninsured status is key—no Medicare Part D or private coverage for Zontivity.[5]

Insurance Requirements

You must be uninsured for prescription drugs or have no coverage for Zontivity. Examples of disqualifying coverage:

  • Private health insurance with drug benefits.
  • Medicare Part D, Medicaid, or VA benefits.
  • Employer plans requiring PAP use.[1][3][5]

If underinsured (high copays/deductibles but some coverage), you likely won't qualify—Merck PAP is for those with no coverage. Call 800-727-5400 to confirm.[2][4]

Step-by-Step Application Process

Applying is straightforward but requires your doctor. Follow these 4 steps:[8]

  1. Check eligibility: Visit merckhelps.com or call 800-727-5400. Download the enrollment form.[2][8]
  2. Fill out your section: Complete Section 1 (personal info), sign/date Sections 2-3. Authorize electronic income check or attach proof (e.g., 1040 tax form, W-2, pay stubs, proof of residency).[1][8]
  3. Doctor completes their part: Take form to prescriber for Sections 4-5, including NPI, prescription details, and signature. Separate script for controlled substances if needed.[1][6][8]
  4. Submit: Mail original form to Merck Patient Assistance Program (address on form). No fax/online for standard PAP—mail only. Copies not accepted.[1][4][6]

Required Documents:

  • Proof of income (electronic OK, or one document like tax return).[1][4]
  • Proof of residency (e.g., utility bill).[Program details]
  • Valid prescription (via doctor's section).[1]

Both you and doctor must sign/date everything.[1][2]

Timeline and Delivery

  • Processing: 2 weeks typically if complete; up to 7 business days or less. Delays if incomplete.[4][7][8] Urgent? Call 800-727-5400.[8]
  • Approval: Notified via mail/phone to you/doctor. Meds shipped directly to your home free for up to 12 months (reauthorization needed).[6][Program details]
  • Refills: Automatic if eligible; new app after 12 months or calendar year limit.[6]

Alternatives if Denied or Ineligible

  • Merck Access Program: For insured patients (copay help); call 855-257-3932.[5][9]
  • RxHope or NeedyMeds: Search other PAPs.[6]
  • State programs, GoodRx discounts, or patient foundation grants.
  • Generic alternatives: None for vorapaxar (brand-only).[Program details]
  • Doctor samples or hospital charity care.

Ask your doctor/pharmacist for options.

Important Disclaimer

This guide is for informational purposes based on available Merck PAP details as of latest sources. Eligibility, terms, and availability can change—always verify directly with Merck at 800-727-5400 or merckhelps.com. Not medical/financial advice. Consult your healthcare provider before starting/stopping Zontivity. Merck may audit/deny/terminate anytime. Program covers U.S. residents only; void where prohibited. Word count: ~950.

Program information last verified: March 30, 2026

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