Zokinvy

Indicated For

Hutchinson-Gilford Progeria Syndrome, processing-deficient Progeroid Laminopathies

About This Medication

# Sentynl Cares Patient Guide: How to Get Zokinvy (lonafarnib) at Low or No Cost ## About Zokinvy (lonafarnib) **Zokinvy** is a prescription medication manufactured by Sentynl Therapeutics, Inc. that treats two rare genetic conditions: Hutchinson-Gilford Progeria Syndrome (HGPS) and processing-deficient Progeroid Laminopathies (PDPL). These conditions occur when the body produces harmful proteins called progerin and progerin-like proteins. Zokinvy is FDA-approved for patients 12 months of age and older with a body surface area (BSA) of 0.39 m² or greater who have a genetically confirmed diagnosis of either condition.[2][10] ## Who Qualifies for Sentynl Cares **Sentynl Cares** is the patient assistance and support program for Zokinvy. To qualify, you must: - Have a genetically confirmed diagnosis of Hutchinson-Gilford Progeria Syndrome or processing-deficient Progeroid Laminopathies[10] - Be a US resident[2] - Be prescribed Zokinvy by a healthcare provider - Be willing to enroll in the program The program serves patients of all ages (starting at 12 months) and provides comprehensive support throughout your treatment journey.[2] ## Income Eligibility Specific income thresholds for Sentynl Cares are not publicly detailed in available program materials. However, the program offers **patient affordability programs** designed to help qualified patients access Zokinvy regardless of insurance status.[1] To learn about your specific eligibility based on household income, contact the Sentynl Cares team directly at the phone number listed below. ## Insurance Requirements and Coverage Support Sentynl Cares works with all insurance types and provides extensive reimbursement support:[1][2] - **Insurance benefits verification** to understand your coverage - **Appeals support** if your insurance initially denies coverage - **Co-pay assistance** for patients with insurance - **Alternate funding options** for uninsured or underinsured patients - **Reimbursement specialist support** to navigate your specific plan If you have Blue Cross Blue Shield or another insurance plan, Sentynl Cares can help coordinate prior authorization requirements and work with your plan to facilitate coverage.[5] ## How to Apply: Step-by-Step ### Step 1: Discuss with Your Healthcare Provider Talk with your doctor about starting Zokinvy. Your provider will need to confirm your genetic diagnosis and determine the appropriate dosage based on your body surface area.[1] ### Step 2: Contact Sentynl Cares Call **1-888-251-2800** Monday through Friday, 8 AM–8 PM ET to begin the enrollment process.[2][10] The Sentynl Cares team will: - Answer questions about the program - Assess your initial eligibility for financial assistance - Guide you through the application process - Provide an enrollment form ### Step 3: Complete the Enrollment Form You or your healthcare provider will need to complete the **Sentynl Cares Zokinvy Enrollment Form**, which includes:[1] - Your personal and contact information - Insurance and coverage information - Your healthcare provider's practice information (NPI number, facility contact details) - Prescription information and ICD-10 codes - Consent for program participation and data use ### Step 4: Submit Your Application Fax the completed, signed enrollment form to **877-977-0011**. All 9 pages must be received to process your enrollment.[1] Alternatively, you can submit through the program website at **ZOKINVY.com/sentynlcares**. ### Step 5: Coordinate with Your Pharmacy Sentynl Cares will coordinate with an authorized specialty pharmacy to dispense your medication. If you need to transfer to a different pharmacy, the Sentynl Cares team can facilitate this process.[5] ## Timeline and Medication Delivery While specific processing timelines are not publicly detailed, Sentynl Cares aims to move quickly. The program: - Processes enrollment forms upon receipt of all required pages[1] - Coordinates prescription fulfillment with authorized specialty pharmacies[1] - Can provide **bridge therapy** if prior authorization is delayed[5] - Ships medication directly to your home or healthcare provider's office[1] For insurance-related delays, check your prior authorization status weekly and respond promptly to any information requests from your insurance company or Sentynl Cares.[5] ## What Happens If Your Application Is Denied If your insurance denies coverage or if you're initially deemed ineligible: 1. **Contact Sentynl Cares immediately** at 1-888-251-2800 to discuss your options 2. **Appeals support**: Sentynl Cares provides appeals specialists who can help challenge insurance denials[2] 3. **Alternate funding**: The program offers alternate funding pathways for patients who don't qualify for standard coverage[2] 4. **External appeals**: If you have Blue Cross Blue Shield in New York, you can file an external appeal through the Department of Financial Services for binding review within 4 months[5] Do not give up—Sentynl Cares is committed to helping you access Zokinvy through multiple pathways. ## Ongoing Support and Reauthorization Once enrolled, Sentynl Cares provides continuous support including: - Ongoing eligibility assessment for financial assistance programs[1] - Prescription refill coordination[1] - Regular contact to ensure you're receiving the support you need[1] - Educational materials about your condition and treatment[2] Reauthorization requirements depend on your specific insurance plan and financial situation. Sentynl Cares will contact you regarding any necessary updates to your enrollment. ## Contact Information **Sentynl Cares Support Team** - **Phone**: 1-888-251-2800 - **Hours**: Monday–Friday, 8 AM–8 PM ET - **Fax**: 877-977-0011 - **Website**: ZOKINVY.com/sentynlcares For after-hours inquiries, follow the recorded instructions for emergency support. ## Important Disclaimer This guide is for educational purposes only and does not constitute medical or legal advice. Coverage decisions depend on your specific insurance plan benefits and clinical circumstances. Always consult with your healthcare provider and insurance plan directly for personalized guidance regarding your eligibility and coverage options.

Program information last verified: March 30, 2026