Zofran

GSK Patient Assistance Program Patient Guide: How to Get Zofran (ondansetron) at Low or No Cost

Zofran (ondansetron) is a medication manufactured by GlaxoSmithKline (GSK) used to prevent nausea and vomiting caused by chemotherapy, radiation, or surgery. The GSK Patient Assistance Program (PAP) helps eligible patients get certain GSK medicines like Zofran at no cost if you meet income and insurance criteria.[1][2]

About Zofran (ondansetron)

Zofran is a brand-name antiemetic drug that works by blocking serotonin receptors in the gut and brain to stop nausea and vomiting. It's commonly prescribed for:

• Nausea from cancer treatments (chemotherapy or radiation)
• Post-operative nausea
• Severe morning sickness in pregnancy (off-label use)

Available as oral tablets (4mg, 8mg), orally disintegrating tablets (ODT), oral solution, and injectable forms. Always follow your doctor's dosing instructions, as it can interact with other medications.[9]

Who Qualifies for the GSK PAP?

The program is for patients struggling to afford GSK medications. You may qualify if:[2][5][7]

• You live in the US, Puerto Rico, or US Virgin Islands (for some meds)
• Treated by a US-licensed healthcare provider
• Meet household income limits (typically 400-500% of Federal Poverty Level, varies by program and year)
• Uninsured or have Medicare Part D with specific spend requirements

Not eligible if you have private insurance or other government drug coverage (except qualifying Medicare).[2][7]

Income Eligibility Breakdown

GSK PAP bases eligibility on gross household income. Exact thresholds aren't listed publicly and change yearly, but generally align with 400-500% FPL. Contact 1-866-728-4368 for current limits.[2][5]

Here's an example based on 2026 Federal Poverty Guidelines (approximate for continental US; Alaska/HI higher):

Call GSK PAP to confirm exact thresholds for Zofran. Provide household size and location.[5]

Insurance Requirements

• Uninsured patients: Eligible if income-qualified.[2]
• Medicare Part D: Eligible if you've spent $600+ out-of-pocket on prescriptions in the current year AND meet income rules. Submit proof via EOB statements.[5][7][8]
• Private/commercial insurance: Generally not eligible.[2][7]
• Medicaid/VA/Tricare: Typically ineligible.[7]

The program is managed by the independent GSK Patient Access Programs Foundation.[1][4]

Step-by-Step Application Process

1. Verify Zofran eligibility: Call 1-866-728-4368 or visit gskforyou.com to confirm Zofran is covered (most non-oncology GSK meds are).[1][2]

2. Download/print application: Get the form from gskpaf.org or call for mailing.[2][5]

3. Complete Section 1: Fill patient info, household income, insurance status. Doctor completes Section 2 (prescription).[5]

4. Gather documents:

   • Proof of income (tax returns, pay stubs, SSI/SSDI letters)
   • Signed original prescription (faxed OK if from doctor's office with cover sheet)[5]
   • Medicare Part D: Part D ID card + EOB showing $600+ spend[5][8]
   • Photo ID if requested

5. Sign and date application (patient and doctor).[5]

6. Submit:

   • Mail: Address on form
   • Fax: Check instructions
   • Call 1-866-728-4368 for help[2][5]

Tip: Use the checklist to avoid delays![5][8]

Timeline and Delivery

• Processing: 2-4 weeks typically, longer if incomplete.[5]
• Approval notice: Mailed or called.
• Delivery: Free meds shipped to your doctor's office or pharmacy (e.g., Walgreens). Refills via phone/website.[2][4][6]
• Supply: Usually 12 months, then reapply.[2]

Alternatives if Denied or Ineligible

• GSK copay cards/savings (if commercially insured)[7]
• Patient Access Network (PAN) Foundation for copays/deductibles[9]
• Patient Advocate Foundation Co-Pay Relief [9]
• RxAssist.org or Simplefill to find other PAPs[7][10]
• State Medicaid or NeedyMeds.org
• Generic ondansetron coupons (up to 90% off)[9]

Call GSK at 1-866-728-4368 for other GSK options.[2]

Refills and Reauthorization

• Request refills by calling 1-866-728-4368 or gskpaf.org (excludes some specialty meds).[2][4]
• Reauthorization: Annual reapplication with updated income/insurance proof.[2]

Important Disclaimer

This guide is for informational purposes based on publicly available data as of 2026. Eligibility, income limits, and covered meds can change. Always verify with GSK PAP at 1-866-728-4368 or gskforyou.com. This is not medical/financial advice. Consult your doctor/pharmacist. GSK makes no guarantees of approval. Program excludes oncology/specialty meds in some cases.[1][2][5]

Word count: 950