← Medication Database
Oncology

Zofran

Generic: ondansetron

Manufacturer: GlaxoSmithKline  ·  Program:

Apply for Assistance

Eligibility Criteria

Insurance Requirement

See program details

Residency

US residency required

Income Threshold

Up to 300% FPL

Individual Income Limit

$43,740/year

Must be uninsured or underinsured

Program Information

Processing Time

2–4 weeks

Delivery Method

shipped to patient, physician office, or participating pharmacy

Application Method

Multiple

Indicated For

Chemotherapy-induced nausea and vomiting (CINV), postoperative nausea and vomiting (PONV)

About This Medication

# GSK Patient Assistance Program Patient Guide: How to Get Zofran (ondansetron) at Low or No Cost Zofran (ondansetron) is a medication manufactured by GlaxoSmithKline (GSK) used to prevent nausea and vomiting caused by chemotherapy, radiation, or surgery. The **GSK Patient Assistance Program (PAP)** helps eligible patients get certain GSK medicines like Zofran at no cost if you meet income and insurance criteria.[1][2] ## About Zofran (ondansetron) **Zofran** is a brand-name antiemetic drug that works by blocking serotonin receptors in the gut and brain to stop nausea and vomiting. It's commonly prescribed for: - Nausea from cancer treatments (chemotherapy or radiation) - Post-operative nausea - Severe morning sickness in pregnancy (off-label use) Available as oral tablets (4mg, 8mg), orally disintegrating tablets (ODT), oral solution, and injectable forms. Always follow your doctor's dosing instructions, as it can interact with other medications.[9] ## Who Qualifies for the GSK PAP? The program is for patients struggling to afford GSK medications. You may qualify if:[2][5][7] - You live in the **US, Puerto Rico, or US Virgin Islands** (for some meds) - Treated by a **US-licensed healthcare provider** - Meet **household income limits** (typically 400-500% of Federal Poverty Level, varies by program and year) - **Uninsured** or have **Medicare Part D** with specific spend requirements **Not eligible** if you have private insurance or other government drug coverage (except qualifying Medicare).[2][7] ## Income Eligibility Breakdown GSK PAP bases eligibility on **gross household income**. Exact thresholds aren't listed publicly and change yearly, but generally align with 400-500% FPL. Contact 1-866-728-4368 for current limits.[2][5] Here's an example based on 2026 Federal Poverty Guidelines (approximate for continental US; Alaska/HI higher): | Household Size | Max Annual Income (400% FPL) | Max Annual Income (500% FPL) | |----------------|------------------------------|------------------------------| | 1 | $60,240 | $75,300 | | 2 | $81,760 | $102,200 | | 3 | $103,280 | $129,100 | | 4 | $124,800 | $156,000 | | +1 person | +$21,520 | +$26,900 | *Call GSK PAP to confirm exact thresholds for Zofran. Provide household size and location.[5]* ## Insurance Requirements - **Uninsured patients**: Eligible if income-qualified.[2] - **Medicare Part D**: Eligible if you've spent **$600+ out-of-pocket** on prescriptions in the current year AND meet income rules. Submit proof via EOB statements.[5][7][8] - **Private/commercial insurance**: Generally **not eligible**.[2][7] - **Medicaid/VA/Tricare**: Typically ineligible.[7] The program is managed by the independent **GSK Patient Access Programs Foundation**.[1][4] ## Step-by-Step Application Process 1. **Verify Zofran eligibility**: Call **1-866-728-4368** or visit **gskforyou.com** to confirm Zofran is covered (most non-oncology GSK meds are).[1][2] 2. **Download/print application**: Get the form from **gskpaf.org** or call for mailing.[2][5] 3. **Complete Section 1**: Fill patient info, household income, insurance status. Doctor completes **Section 2** (prescription).[5] 4. **Gather documents**: - **Proof of income** (tax returns, pay stubs, SSI/SSDI letters) - **Signed original prescription** (faxed OK if from doctor's office with cover sheet)[5] - **Medicare Part D**: Part D ID card + EOB showing $600+ spend[5][8] - Photo ID if requested 5. **Sign and date** application (patient and doctor).[5] 6. **Submit**: - **Mail**: Address on form - **Fax**: Check instructions - Call 1-866-728-4368 for help[2][5] **Tip**: Use the checklist to avoid delays![5][8] ## Timeline and Delivery - **Processing**: 2-4 weeks typically, longer if incomplete.[5] - **Approval notice**: Mailed or called. - **Delivery**: Free meds shipped to your **doctor's office** or **pharmacy** (e.g., Walgreens). Refills via phone/website.[2][4][6] - **Supply**: Usually 12 months, then reapply.[2] ## Alternatives if Denied or Ineligible - **GSK copay cards/savings** (if commercially insured)[7] - **Patient Access Network (PAN) Foundation** for copays/deductibles[9] - **Patient Advocate Foundation Co-Pay Relief** [9] - **RxAssist.org** or **Simplefill** to find other PAPs[7][10] - **State Medicaid** or **NeedyMeds.org** - **Generic ondansetron** coupons (up to 90% off)[9] Call GSK at 1-866-728-4368 for other GSK options.[2] ## Refills and Reauthorization - Request refills by calling **1-866-728-4368** or **gskpaf.org** (excludes some specialty meds).[2][4] - **Reauthorization**: Annual reapplication with updated income/insurance proof.[2] ## Important Disclaimer This guide is for informational purposes based on publicly available data as of 2026. **Eligibility, income limits, and covered meds can change**. Always verify with GSK PAP at 1-866-728-4368 or gskforyou.com. This is **not medical/financial advice**. Consult your doctor/pharmacist. GSK makes no guarantees of approval. Program excludes oncology/specialty meds in some cases.[1][2][5] *Word count: 950*

Program information last verified: March 30, 2026

Ready to apply for Zofran assistance?

ProvisionRX manages the complete application process. Start your application in about 15 minutes.

Start My ApplicationBrowse All Medications