Zirabev

Indicated For

colorectal cancer, lung cancer, glioblastoma, hepatocellular carcinoma, other cancers

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get Zirabev (bevacizumab-bvzr) at Low or No Cost Zirabev (bevacizumab-bvzr) is a prescription oncology medicine used to treat certain types of cancer, and Pfizer's Patient Assistance Program (PPAP) offers it **free** to eligible uninsured or publicly insured patients struggling with costs.[1][2][4] This guide explains eligibility, application steps, and support options in simple terms to help you access treatment without financial stress. ## About Zirabev and Why Assistance Matters **Zirabev** is an injectable biosimilar to Avastin (bevacizumab), approved for cancers like colorectal, lung, kidney, cervical, and ovarian cancers, often combined with chemotherapy.[4] It works by blocking a protein that helps tumors grow blood vessels, slowing cancer spread. As an infusion given in a doctor's office or clinic, costs can exceed thousands per dose without help—making programs like PPAP essential for affordability.[1][2] PPAP, part of Pfizer RxPathways, provides **free Pfizer medicines**, including Zirabev, to qualified patients via doctor's office or home delivery.[1][9] It's designed for those without commercial insurance or unable to pay copays on public insurance. Note: Eligibility rules can change; always verify at pfizerrxpathways.com or by calling 1-844-989-PATH (7284).[1][9] ## Who Qualifies for the Program? Eligibility focuses on insurance status, income, residency, and prescription validity. Key requirements:[1][2][6] - **Uninsured or publicly insured** (Medicare, Medicaid, TRICARE, VA) with unaffordable out-of-pocket costs. **Commercial insurance excludes you** from free medicine.[1][2] - U.S. resident (or applicable territory) with a valid U.S.-licensed provider prescription for outpatient use.[1] - FDA-approved indication for Zirabev.[1] - For Institutional PPAP (via clinics/hospitals): No prescription coverage and ≤300% Federal Poverty Level (FPL).[1] **Income Eligibility Breakdown** Income limits vary by program arm and medicine, often **≤300%-500% FPL** adjusted for household size. Exact thresholds for Zirabev aren't specified publicly—contact Pfizer for your case. Here's a general FPL table (2026 estimates; check HHS.gov for updates):[1][6] | Household Size | 300% FPL | 400% FPL | 500% FPL | |----------------|----------|----------|----------| | 1 (Individual) | ~$45,180 | ~$60,240 | ~$75,300 | | 2 (Couple) | ~$61,320 | ~$81,760 | ~$102,200| | 3 | ~$77,460 | ~$103,280| ~$129,100| | 4 | ~$93,600 | ~$124,800| ~$156,000| *Add ~$16,140 per extra person for 300% FPL. Proof like W-2, paystub, or tax return required.*[1] Migrant/homeless presumed eligible for Institutional program.[1] ## Insurance Requirements - **No commercial insurance**: Patients with job-based or marketplace plans don't qualify for free PPAP medicine.[2] - **Public insurance OK**: Medicare/Medicaid patients may get help if copays are unaffordable. Exhaust other aid first (e.g., Medicare Extra Help).[2] - **Uninsured preferred** for Institutional PPAP.[1] Commercially insured? Explore **Pfizer Oncology Together Co-Pay Program** instead: $0/month up to $25,000/year savings (call 1-844-722-6672).[3][5] Medicare patients: Check Extra Help or Payment Plan first.[2] ## Step-by-Step Application Process 1. **Confirm eligibility**: Review criteria above. Discuss with your doctor—prescription must be for outpatient FDA-approved use.[1] 2. **Gather documents**: Valid prescription, proof of income (W-2, paystub, tax return), ID/residency proof. List may vary.[1] 3. **Get the form**: Download from pfizerrxpathways.com/resources/patients or call 1-844-989-PATH (7284). Doctor completes enrollment with you.[1][9] 4. **Submit**: Patient/doctor mails/faxes/uploads form + docs. Some oncology meds require trying other aid first.[1] 5. **Track status**: Call program for updates. Approval means free medicine for up to 1 year (renewable).[8] For Institutional PPAP, visit participating clinic/hospital.[1] ## Timeline and Delivery Processing takes **2-4 weeks** typically, but varies. Once approved, medicine ships to doctor's office or home.[1] Refills/reauthorization needed annually or per cycle—doctor resubmits.[1][8] Delays possible if docs incomplete. ## Alternatives if Denied or Ineligible - **Co-Pay Programs**: Pfizer Oncology Together for commercial insurance ($4K-$25K/year).[3][5] - **Biosimilars/Reference**: Avastin (bevacizumab) may have similar aid.[4] - **Other Resources**: RxAssist.org, NeedyMeds, or PAN Foundation. State programs, 340B clinics.[7][9] - **Appeal**: Resubmit with more info or try Institutional PPAP.[1] ## Disclaimer This guide summarizes public info as of 2026; **not official advice**. Eligibility/terms change—contact Pfizer directly (1-844-989-PATH). Consult your doctor/healthcare team. Program doesn't guarantee approval or cover non-FDA uses. Pfizer disclaims liability for decisions based on this.[1][2]

Program information last verified: March 30, 2026