ZIMHI

Indicated For

opioid overdose

About This Medication

# ZIMHI Patient Guide: How to Get ZIMHI at Low or No Cost ZIMHI (naloxone HCl injection) is a high-dose injectable opioid antagonist used for emergency treatment of known or suspected opioid overdoses in adults and children, reversing respiratory and central nervous system depression.[2][3] This guide explains how patients can access ZIMHI through manufacturer savings options from US WorldMeds, focusing on cost-saving programs for commercially insured individuals, since no traditional income-based patient assistance program with specific eligibility thresholds is currently detailed.[6] ## About ZIMHI **ZIMHI** delivers the highest dose of naloxone available as an intramuscular injection, designed for rapid absorption into the bloodstream during critical opioid overdose situations.[2] Unlike nasal sprays like Narcan, ZIMHI's 5 mg dose per 0.5 mL may be particularly useful for overdoses involving potent synthetic opioids like fentanyl, where multiple doses are often needed.[8] It is indicated for immediate use in settings where opioids are present, but its effects are shorter than many opioids, so repeated doses and medical follow-up are essential.[3][5] Administer ZIMHI by injecting into the thigh muscle or under the skin. Lay the person on their back, pull down pants if needed, and inject firmly. Call 911 immediately after use, as monitoring is required.[9] Common side effects include withdrawal symptoms like nausea, sweating, and agitation in opioid-dependent individuals. Report adverse reactions to 1-800-230-3935 or FDA at 1-800-FDA-1088.[2] Healthcare providers often co-prescribe ZIMHI with opioids, and in many states, naloxone is available without a prescription.[5] Pharmacists can help ensure patients leave with ZIMHI, especially for high-dose opioid scripts.[5] ## Who Qualifies for Savings US WorldMeds offers a **Prescription Savings Program** primarily for **commercially insured patients**, helping reduce out-of-pocket costs on ZIMHI prescriptions.[6][8] This is not a free drug program for uninsured or low-income patients with strict federal poverty level (FPL) guidelines; no specific income thresholds (e.g., 400% FPL for individuals or families) are published.[6] Eligibility focuses on commercial insurance coverage rather than income. Uninsured patients may use discount cards at participating pharmacies via Change Healthcare or Relay Health, but savings vary and may not cover full cost.[6] Medicare patients are typically ineligible for manufacturer copay cards, though coverage depends on your plan.[8] Contact your provider or pharmacy for details. ## Income Eligibility Breakdown No formal income-based assistance program exists with defined FPL limits. Here's a general overview of common patient assistance structures for context (ZIMHI does not match these exactly): | Household Size | Typical 400% FPL Threshold (2026 est.) | ZIMHI Program Fit | |---------------|---------------------------------------|-------------------| | Individual | ~$60,000 annually | Not income-based; commercial insurance focus[6] | | Couple | ~$81,000 annually | Not income-based; commercial insurance focus[6] | | Family of 3 | ~$102,000 annually | Not income-based; commercial insurance focus[6] | | Family of 4 | ~$123,000 annually | Not income-based; commercial insurance focus[6] | *Notes: FPL estimates adjusted for inflation; ZIMHI savings prioritize insurance status over income. Uninsured may get pharmacy discounts.[6][8]* ## Insurance Requirements The **Prescription Savings Program** is for **commercially insured patients** (e.g., employer or marketplace plans).[6] Present the savings card ID at the pharmacy for automatic discounts processed by Change Healthcare or Relay Health—no physical card needed if bookmarked on your phone.[6] **Medicare, Medicaid, or government insurance**: Likely ineligible for the copay card; check your plan for coverage. ZIMHI may require prior authorization for some plans post-limit.[4] Contact your insurer or 1-800-MEDICARE for options.[8] ## Step-by-Step Application 1. **Get Prescribed**: Ask your doctor or pharmacist for ZIMHI, especially with opioid prescriptions. Many states allow naloxone without Rx.[5] 2. **Access Savings Card**: Visit zimhi.com/hcp-patient-savings/ or have your HCP provide it. Print or save the ID digitally.[6] 3. **Fill at Pharmacy**: Provide the ID number. Discounts apply automatically at participating locations.[6] 4. **No Online App Needed**: Unlike PAPs, this is pharmacy-based—no forms, income proof, or mailed meds.[6] For uninsured/low-income help, explore state programs, GoodRx (up to 75% off similar naloxone), or SAMHSA Helpline (1-800-662-HELP).[1][8] ## Timeline and Delivery **Processing**: Instant at pharmacy—show card, get discount on filled Rx.[6] No waiting for approval letters. **Delivery**: Pick up same-day at most pharmacies. Home delivery via mail-order if offered by your plan/pharmacy. Refills: ZIMHI is for emergency use; restock as needed. No set reauthorization, but check expiration (typically 2 years).[3] ## Alternatives if Denied or Ineligible - **Narcan Nasal Spray**: OTC, ~$45 for 2-pack; generic cheaper with GoodRx (~$44).[8] - **Other Naloxone**: Evzio, Kloxxado—check insurance PA policies.[4] - **Free/Standing Orders**: Many states offer free naloxone via public health programs.[5] - **GoodRx Coupons**: Save on ZIMHI if uninsured.[8] - **SAMHSA Helpline**: Free referral to local resources.[1] No biosimilars listed; all naloxone products are equivalents.[8] ## Disclaimer This guide is for informational purposes only and not medical/financial advice. Eligibility and savings vary; confirm with US WorldMeds (1-800-230-3935), your pharmacy, or insurer.[2] Programs can change—verify at zimhi.com. Always seek emergency help post-naloxone; ZIMHI is not a cure for addiction. Consult HCP for personalized guidance. Word count: 1028.

Program information last verified: March 30, 2026