Zerbaxa
Generic: ceftolozane tazobactam
Manufacturer: Merck · Program: Merck Patient Assistance Program
Apply for assistanceFree to apply. Service from $40/month, payable only when your application is ready to submit.
Eligibility Criteria
Insurance Requirement
Indigent and uninsured patients; patients with certain insurance plans involving alternative funding programs are not eligible
Residency
US resident
Income Threshold
Up to 400% FPL
Individual Income Limit
$58,320/year
Must be uninsured or have inadequate coverage
Program Information
Processing Time
2–3 weeks
Delivery Method
shipped to patient or physician office
Application Method
Multiple
Indicated for
complicated intra-abdominal infections, complicated urinary tract infections, hospital-acquired bacterial pneumonia, ventilator-associated bacterial pneumonia
About This Medication
Merck Patient Assistance Program Patient Guide: How to Get Zerbaxa at Low or No Cost
About This Program
The Merck Patient Assistance Program (Merck PAP) is designed to help uninsured and indigent patients access Merck medications, including Zerbaxa (ceftolozane/tazobactam), at no cost. Zerbaxa is an antibiotic combination used to treat complicated urinary tract infections and complicated intra-abdominal infections caused by susceptible bacteria. If you cannot afford your prescribed Zerbaxa, this program may be able to help.
Who Qualifies for Merck PAP
To be eligible for the Merck Patient Assistance Program, you must meet ALL of the following requirements:
- US Residency: You must currently reside in the United States or a US territory (you do not need to be a US citizen)
- Valid Prescription: A licensed US healthcare provider must have prescribed you Zerbaxa
- Insurance Status: You must be uninsured or indigent. Patients with certain insurance plans—particularly those involving alternative funding programs that require or encourage PAP enrollment as a condition—are not eligible
- Financial Need: You must meet the program's financial eligibility criteria, which are designed for patients with limited income and resources
Income Eligibility
The Merck PAP uses financial criteria to determine eligibility, though specific income thresholds are not publicly listed. The program is specifically designed for indigent and uninsured patients. Your household income and current insurance status will be evaluated during the application process.
If you authorize the program, Merck PAP can conduct an electronic income verification through a consumer report, which will not affect your credit rating. Alternatively, you can provide one of the following documents as proof of household income:
- Recent tax return
- Pay stubs
- Proof of unemployment or disability benefits
- Bank statements
- Other documentation of household financial status
Insurance Requirements
You are eligible for Merck PAP if you:
- Have no insurance coverage for Zerbaxa, OR
- Are enrolled in certain insurance plans that do not cover this medication
You are NOT eligible if:
- Your insurance plan participates in or is involved with an alternative funding program that requires or encourages you to apply to Merck PAP as a condition of coverage
- Your employer offers coverage through a plan with such alternative funding arrangements
If you have Medicare, Medicaid, or private insurance that covers Zerbaxa, you may not qualify unless your plan specifically excludes this medication.
How to Apply: Step-by-Step
Step 1: Call to Request an Application
Contact the Merck Patient Assistance Program by phone:
Phone: (888) 727-9535
A program representative will answer your questions and can mail or email you an enrollment form. You can also download the form from MerckHelps.com.
Step 2: Complete Your Section of the Application
Fill out all sections of the enrollment form that apply to you (typically Section 1, and sign Sections 2 and 3). You can:
- Fill in the form online and print it, OR
- Print the form and complete it by hand using a black ballpoint pen
Make sure to include:
- Your full name and contact information
- Your household income information
- Authorization for income verification (either electronic or by providing supporting documents)
- Your signature and date in all designated areas
Step 3: Have Your Healthcare Provider Complete Their Section
Give the partially completed form to your prescribing healthcare provider. They must:
- Complete Section 4 and Section 5 of the enrollment form
- Include their National Provider Identifier (NPI) number
- Sign and date all designated areas
- For controlled substances, provide a separate prescription written according to state dispensing laws
Step 4: Submit Your Completed Application
Once both you and your healthcare provider have completed, signed, and dated all sections, submit the original form by:
- Faxing to the Merck PAP fax number (provided on the form), OR
- Mailing to the Merck Patient Assistance Program address (listed on the form)
Keep a copy for your records.
Step 5: Receive Approval Notification
If you provided your email address on the application, you will receive an email confirming that Merck PAP received your enrollment form. You will be notified of your eligibility status once the program completes its review.
Processing Timeline
The Merck Patient Assistance Program typically processes completed enrollment forms within 2-3 business days if:
- All fields are completely filled out
- All signature fields are signed and dated
- You are eligible for the program
- All required documentation is included
Processing times may be longer if your form is incomplete or if additional information is needed. For urgent medication needs, call the program directly at (888) 727-9535 to discuss expedited options.
What Happens After Approval
Once approved, the Merck PAP will arrange for your Zerbaxa to be provided at no cost. The program will work with your healthcare provider and pharmacy to ensure you receive your medication. Each application is valid for up to 12 months; after that time, you may need to reapply if you continue to meet eligibility criteria.
What If Your Application Is Denied
If you are not approved for Merck PAP, the program will provide information about why you were not eligible. Common reasons include:
- Having insurance coverage for Zerbaxa
- Not meeting the financial eligibility criteria
- Enrollment in an alternative funding program
- Incomplete application information
If denied, ask the program about:
- Whether you can reapply if your circumstances change
- Other patient assistance resources
- Whether your healthcare provider can help you explore other options
- Manufacturer rebate programs or other cost-reduction strategies
Important Reminders
- A separate application is required for each patient
- You must have a valid prescription from a US-licensed healthcare provider
- The program requires authorization to share your medical and financial information with healthcare providers, pharmacies, and health plans to administer the program
- This program is for patients who cannot otherwise afford their medication
Contact Information
Merck Patient Assistance Program
Phone: (888) 727-9535
Website: MerckHelps.com
Hours: Monday–Friday, 8 AM–8 PM ET
Disclaimer
This guide provides general information about the Merck Patient Assistance Program for Zerbaxa. Eligibility requirements, application procedures, and program terms are subject to change. For the most current and complete information, contact the Merck Patient Assistance Program directly or visit MerckHelps.com. This guide is not a guarantee of program enrollment or medication provision. Always consult with your healthcare provider about your treatment options and medication access.
Program information last verified: March 30, 2026
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