ZEPZELCA
Generic: lurbinectedin
Manufacturer: Jazz Pharmaceuticals · Program: JazzCares
Apply for AssistanceEligibility Criteria
Insurance Requirement
Uninsured or underinsured patients
Residency
US resident
Income Threshold
Up to 400% FPL
Individual Income Limit
$58,320/year
Program Information
Processing Time
2–3 weeks
Delivery Method
shipped to patient or physician office
Application Method
Multiple
Indicated For
Small Cell Lung Cancer, SCLC 2nd line
About This Medication
# JazzCares Patient Guide: How to Get ZEPZELCA at Low or No Cost ZEPZELCA (lurbinectedin) is an intravenous chemotherapy medication approved by the FDA for treating metastatic small cell lung cancer (SCLC) in adults who have progressed on or after platinum-based chemotherapy. JazzCares, offered by Jazz Pharmaceuticals, provides financial assistance including free medication for eligible uninsured or underinsured patients meeting financial criteria.[5][9] ## About ZEPZELCA **ZEPZELCA** is used as a monotherapy for adults with metastatic SCLC that has worsened after prior platinum-containing therapy. Administered by a healthcare professional via IV infusion over 60 minutes every 21 days, it targets cancer cells by binding to DNA and inhibiting tumor growth. Common side effects include fatigue, nausea, decreased appetite, musculoskeletal pain, and low blood cell counts, which require monitoring. Always consult your doctor for personalized advice on treatment and risks.[5] ## Who Qualifies for JazzCares? JazzCares helps patients access ZEPZELCA through various programs, focusing on those facing financial barriers. The **Patient Assistance Program (PAP)** offers free medication to **uninsured or underinsured patients** who meet **financial criteria** and U.S. residency requirements. Eligibility emphasizes lack of coverage rather than strict income caps, though income verification is required. Commercial insurance patients may qualify for a **Savings Card** reducing costs to as low as $10 per prescription (with annual limits).[5][1][2] ## Income Eligibility Breakdown Specific Federal Poverty Level (FPL) percentages or household size thresholds are not publicly detailed for ZEPZELCA, but programs target those with limited resources. Applicants must prove financial need via household income documents. Here's a general overview based on JazzCares patterns: | Household Type | Typical Eligibility Notes | Required Proof | |---------------|---------------------------|---------------| | **Individual** | Uninsured/underinsured meeting financial criteria | Tax returns, W-2s, pay stubs, benefit statements[4] | | **Couple** | Same as above; all earners' income counted | Same as above, for household[4] | | **Family of 3** | Household income verification required | Bank statements, unemployment letters[4] | | **Family of 4+** | No income or low income supported by letter if needed | Social worker/prescriber letter for zero income[4] | *Notes: No fixed FPL % listed; 'certain financial criteria' apply. Zero-income patients can submit support letters from family/clergy.[4][5][9]* ## Insurance Requirements - **Uninsured patients**: Eligible for free ZEPZELCA via PAP if financial criteria met.[5][6][9] - **Underinsured patients**: Those with insurance not covering ZEPZELCA or high out-of-pocket costs may qualify.[1][2] - **Commercially insured**: Savings Card for low copays (e.g., $10 max).[5] - **Government insurance (Medicare, Medicaid, VA)**: Generally ineligible for PAP; other options explored.[4] JazzCares verifies coverage and refers to suitable programs.[2][8] ## Step-by-Step Application Process 1. **Discuss with your doctor**: Confirm ZEPZELCA prescription and JazzCares suitability. Your prescriber initiates enrollment.[4][5] 2. **Call JazzCares**: Dial **(833) 533-5299** (Mon-Fri, 8am-8pm ET) for guidance, eligibility screening, and application start. Phone is primary method.[1][5] 3. **Gather documents**: Prepare proof of income (tax forms, W-2s, pay stubs, 1099s, bank statements), insurance card (front/back), photo ID/SSN, prescription.[4] 4. **Complete enrollment**: Prescriber fills sections on income, insurance, prescription. Patient signs authorization for data use and program enrollment.[3][4] 5. **Submit**: Via phone support; fax or electronic options may apply (e.g., 1-855-518-7566 for similar programs).[3] 6. **Await approval**: JazzCares reviews; no guarantee.[4] ## Timeline and Delivery Processing time varies; expect days to weeks based on completeness. Bridge-like programs offer interim supply while awaiting approval (up to 120 days in similar cases).[2][7] Approved medication is **shipped free to your home or doctor's office**.[5] Refills require reauthorization; prescriber recertifies periodically.[4] ## Alternatives if Denied - **Appeal**: Contact JazzCares for review or additional docs.[1] - **Other foundations**: Referred by JazzCares to patient advocacy groups.[3] - **Savings Card** (if commercially insured).[5] - **Generic/biosimilars**: None available for ZEPZELCA.[5] - **State programs**: Ask about local assistance for SCLC patients. ## Disclaimer This guide summarizes JazzCares for ZEPZELCA based on available info as of 2026. Programs can change; eligibility not guaranteed. Jazz Pharmaceuticals may modify/terminate anytime. Consult healthcare provider and call (833) 533-5299 for latest details. Not medical/financial advice. Income estimates approximate 950 words.
Program information last verified: March 30, 2026
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