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Neurology

Zeposia

Generic: ozanimod

Manufacturer: Bristol Myers Squibb  ·  Program:

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Eligibility Criteria

Insurance Requirement

See program details

Residency

US residency required

Income Threshold

Up to 300% FPL

Individual Income Limit

$43,740/year

Must be uninsured or have inadequate coverage

Program Information

Processing Time

2–4 weeks

Delivery Method

shipped to patient, physician office, or participating pharmacy

Application Method

Multiple

Indicated For

relapsing multiple sclerosis, ulcerative colitis

About This Medication

# Zeposia Patient Assistance Guide: How to Get Zeposia at Low or No Cost Zeposia (ozanimod) is a once-daily oral medication approved for adults with relapsing forms of multiple sclerosis (MS). Bristol Myers Squibb (BMS) offers support through programs like ZEPOSIA 360 Support™, BMS Access Support, and the independent Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) to help eligible patients access it at low or no cost.[1][2][4] ## About Zeposia **Zeposia** is a sphingosine 1-phosphate (S1P) receptor modulator taken as a **once-daily pill** to reduce MS relapses, slow disability progression, and manage active MS lesions. It's prescribed for relapsing-remitting MS (RRMS), active secondary progressive MS (SPMS), and sometimes ulcerative colitis. Treatment starts with a 7-day titration pack to minimize side effects like heart rate slowing, headaches, infections, or liver issues. Your doctor will monitor you closely, especially at the start, with required baseline assessments (e.g., cardiac, liver, eye exams). Always follow your healthcare provider's instructions.[2][7] ## Who Qualifies for Assistance? BMS provides tiered support based on insurance and finances: - **Commercially insured patients**: ZEPOSIA 360 Support™ and BMS Access Support Co-Pay Program cover out-of-pocket costs (deductibles, co-pays, co-insurance) up to $25,000 per calendar year per medication for eligible U.S. residents. Not for government insurance like Medicare/Medicaid.[2][5][7][8] - **Uninsured or underinsured**: BMSPAF offers free BMS medications temporarily if you lack prescription coverage, meet income limits (often ≤400-500% Federal Poverty Level, though exact thresholds vary; check current guidelines), and reside in the U.S.[1][4][6] - **Bridge Program**: If coverage is delayed/denied, commercially insured patients may get up to 2 years of free Zeposia.[7] **Key eligibility notes**: 18+ years old, U.S. resident, prescribed Zeposia. Government-insured patients may qualify for independent foundations via BMS referrals.[5] ## Income Eligibility Breakdown BMSPAF targets low-income patients without insurance coverage. Exact thresholds aren't publicly fixed but typically align with FPL. Contact programs for personalized review. Here's a general guide based on 2026 FPL estimates (adjust for household size/inflation): | Household Size | Annual Income Limit (approx. 400% FPL) | Notes | |---------------|---------------------------------------|-------| | 1 (Individual) | $60,000 | Uninsured/underinsured only [1][6] | | 2 (Couple) | $81,000 | Varies by program; call to confirm | | 3 | $102,000 | Temporary help; reapply as needed | | 4 | $123,000 | Excludes government insurance [4] | *Table is illustrative; actual limits per BMSPAF guidelines. Higher limits possible for co-pay programs.*[1][4] ## Insurance Requirements - **Commercial/Private Insurance**: Eligible for co-pay cards/Bridge/Starter Kit. Program verifies benefits (usually within 24 hours).[5][7][8] - **Medicare/Medicaid/TRICARE**: Ineligible for BMS co-pay programs. BMS connects to independent charities.[5] - **No Insurance**: BMSPAF primary option for free meds.[1][6] ZEPOSIA 360 Support™ handles prior authorizations, appeals, and cost estimates via dedicated coordinators.[2] ## Step-by-Step Application Process 1. **Get Prescribed**: Discuss Zeposia with your doctor. They submit the Start Form (prescription) to ZEPOSIA 360 Support™.[2][7] 2. **Contact Support**: Call **1-833-ZEPOSIA (1-833-937-6742)** Mon-Fri 8 AM-8 PM ET or **1-800-861-0048** for BMS Access. A coordinator reaches out post-prescription.[2][8] 3. **Enroll**: Provide insurance details, income proof (tax returns, pay stubs), ID. For BMSPAF, apply at www.bmspaf.org.[1][4] 4. **Baseline Assessments**: Eligible patients get free in-home/office checks (ECG, bloodwork). Reimbursed if out-of-pocket.[7] 5. **Approval**: Receive Starter Kit (7+21 doses) if new and eligible. Full supply follows.[7] 6. **Refills**: Auto-ship or pharmacy pickup; reauthorize periodically.[7] Visit zeposia.com or bmsaccesssupport.com for forms.[2][5] ## Timeline and Delivery - **Benefits Verification**: Median 24 hours.[8] - **Approval**: 1-2 weeks for co-pay/Bridge; BMSPAF may take longer (2-4 weeks).[1][7] - **Delivery**: Starter Kit to you/office; ongoing via mail/specialty pharmacy. Free shipping typical.[2][7] Track via coordinator or portal. ## Alternatives if Denied - **Appeal Coverage**: ZEPOSIA 360 assists with PA/appeals.[2] - **Bridge Program**: Up to 2 years free during delays.[7] - **Independent Foundations**: BMS refers (e.g., Patient Access Network, HealthWell).[5] - **Generic/Biosimilars**: None currently; discuss alternatives like fingolimod or siponimod with doctor.[7] - **State Programs/NeedyMeds**: Search needymeds.org.[6] - **Samples**: Ask provider.[7] ## Disclaimer This guide is for informational purposes only and not medical/financial advice. Eligibility, terms, and availability change; confirm with programs. BMS cannot guarantee assistance. Consult your doctor for treatment suitability. See full Prescribing Info at zeposiahcp.com. Programs for U.S. residents 18+ only. Word count: 950.[1][2][4][5][7]

Program information last verified: March 30, 2026

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