ZENPEP

Zenpep and Viokace Patient Assistance Program: How to Get Pancrelipase at Low or No Cost

About This Program

The Zenpep and Viokace Patient Assistance Program, administered by Nestlé Health Science, provides free pancrelipase medication to eligible patients who cannot afford their prescriptions. Pancrelipase is a digestive enzyme replacement used to treat exocrine pancreatic insufficiency (EPI)—a condition where the pancreas cannot produce enough enzymes to digest food properly. This program ensures that financial barriers do not prevent patients from accessing this essential medication.

Who Qualifies for This Program?

You may be eligible if you meet the following criteria:

• Insurance Status: You are uninsured or underinsured (meaning your insurance does not adequately cover Zenpep or Viokace)
• Medicare Patients: If you have Medicare, your household income must be below 150% of the Federal Poverty Level (FPL), and you must have been denied for the Extra Help Program
• Residency: You are a resident of the United States or Puerto Rico
• Valid Prescription: You have a current prescription from a licensed healthcare provider for a three-month supply of the medication

Income Eligibility

While specific income thresholds are not publicly listed for most patients, Medicare beneficiaries must have household income below 150% of the Federal Poverty Level. The program uses a needs-based assessment, meaning your household income and financial situation are evaluated during the application process.

2026 Federal Poverty Level Guidelines (150% threshold)

Note: These figures are based on 2026 FPL guidelines. Contact the program for current thresholds.

Insurance Requirements

The program is designed for:

• Uninsured patients with no health insurance coverage
• Underinsured patients whose insurance does not adequately cover Zenpep or Viokace
• Medicare patients with income below 150% FPL who have been denied for the Extra Help Program
• Medicaid patients who may qualify depending on coverage gaps

If you have commercial insurance, you may want to explore the Z-SAVE program (a separate copay assistance program for commercially insured patients) before applying to the patient assistance program.

Step-by-Step Application Process

Step 1: Gather Required Documents

Before starting your application, collect the following:

• A valid prescription from your licensed healthcare provider written for a three-month supply of Zenpep or Viokace
• Proof of your gross monthly household income (examples include federal tax return, W-2, current pay stubs, Social Security award letter, or bank statement showing monthly direct deposit)
• Any additional documentation of healthcare benefits or financial hardship

Step 2: Complete the Application Form

You and your healthcare provider must complete the official application form together. The form includes:

• Patient Information: Your name, contact information, and date of birth
• Income Information: Your household income and family size
• Coverage Information: Details about your current insurance (or confirmation that you are uninsured)
• Patient Certification: Your signature confirming the information is accurate
• Patient Authorization: Your signature authorizing the program to process your request (valid for 12 months)

If you are unable to sign the application, a notarized Power of Attorney (POA) form may be submitted on your behalf.

Step 3: Submit Your Application

You have three options for submission:

By Fax (fastest option):

• Fax number: 1-877-867-1831
• Important: Applications must be faxed from your physician's office with their fax banner attached

By Mail:

• Zenpep and Viokace Patient Assistance Program
• PO BOX 66520
• St. Louis, MO 63166

By Phone:

• Call 1-855-210-6228 (Monday–Friday, 8 AM–5 PM US Central Time) to request that an application be mailed, faxed, or emailed to you

Step 4: Wait for Approval Notification

After the program receives your completed application, they will review your eligibility. Notification of approval or denial will be sent to both your healthcare provider and you.

Timeline and Medication Delivery

Processing Time: Allow up to 4 weeks for application processing and delivery of your medication.

Medication Delivery: Once approved, a 30-day or 90-day supply of your requested medication will be shipped directly to your licensed healthcare provider's office for dispensing. You will pick up the medication from your provider as you normally would.

Enrollment Duration:

• Non-Medicare patients: Approved for 12 months of coverage
• Medicare patients: Approved until the end of the calendar year in which you are approved

Cost

If you are approved, there is no cost for any medications received through this program.

What If Your Application Is Denied?

If your application is denied, you have the right to appeal. To appeal, you must submit:

• A letter from your physician explaining the medical necessity of the medication
• A detailed budget and expense statement from you, including household breakdown
• Proof of your out-of-pocket costs

Submit your appeal materials to the same address or fax number as your original application.

Reauthorization and Refills

Your enrollment lasts for either 12 months (non-Medicare patients) or until the end of the calendar year (Medicare patients). Before your coverage expires, you will need to reapply with an updated application and current proof of income to continue receiving free medication through the program.

Alternative Assistance Programs

If you do not qualify for the patient assistance program or are denied, consider these alternatives:

• Z-SAVE Program: For commercially insured patients, eligible patients may pay as little as $0 for their first prescription and $30 for refills, plus receive free nutritional supplements. Call 1-844-476-7221 for more information.
• LIVE2THRIVE Program: For cystic fibrosis patients. Call 1-888-936-7371 or visit www.live2thrive.org.
• Simplefill: A third-party assistance service that can help match you to available programs. Call 1-877-386-0206 or complete an online application.

Important Disclaimer

This guide provides general information about the Zenpep and Viokace Patient Assistance Program based on publicly available information as of March 2026. Program eligibility, requirements, and benefits may change. For the most current and accurate information, contact the program directly at 1-855-210-6228 or visit the official Nestlé Health Science website. Always consult with your healthcare provider about your specific situation and eligibility.