ZELBORAF

Indicated For

melanoma

About This Medication

# **Genentech Patient Foundation** Patient Guide: How to Get **ZELBORAF (vemurafenib)** at Low or No Cost This guide explains how the **Genentech Patient Foundation** can help you access **ZELBORAF (vemurafenib)**, a targeted therapy for certain types of melanoma, at little or no cost if you meet eligibility rules. It covers qualifications, steps to apply, and what to do next, written in simple terms for patients. ## About ZELBORAF (vemurafenib) **ZELBORAF (vemurafenib)** is an oral prescription medicine used to treat melanoma, a serious form of skin cancer, in adults and children 12 years and older with **BRAF V600E mutation** as detected by an FDA-approved test. It works by blocking abnormal signals in cancer cells with this specific genetic mutation, helping to slow or stop cancer growth. Your doctor will confirm if this mutation is present through a tumor biopsy test before prescribing it. Common side effects include joint pain, rash, hair loss, nausea, and sensitivity to sunlight—always discuss risks with your oncologist. ZELBORAF is taken twice daily with or without food, but follow your prescriber's exact instructions. This program provides **free medicine** through the Genentech Patient Foundation, run by **Genentech**, for eligible patients facing high costs.[1][2] ## Who Qualifies? The **Genentech Patient Foundation** helps **U.S. residents** treated by a **U.S.-licensed physician** who have limited insurance coverage or financial hardship for Genentech medicines like ZELBORAF. No citizenship or immigration info is required.[3][4] Key groups: - **Uninsured patients** or those **without coverage for the medicine**. - **Insured patients** who have coverage but must first try other assistance options if available, and meet income limits. You generally qualify if your **household income is under $150,000** (with adjustments for household size) *or* if insured with an **out-of-pocket maximum over 7.5% of yearly income**. Exact Federal Poverty Level (FPL) percentages aren't fixed but are assessed case-by-case. Call (888) 941-3331 for a pre-screen.[2][4][6] ## Income Eligibility Breakdown Income rules differ by insurance status. Use this table as a guide—final approval depends on full review.[4] | Household Size | Uninsured/ No Coverage for Medicine (Max Income) | Insured with Coverage (Max Income or OOP >7.5%) | |----------------|--------------------------------------------------|------------------------------------------------| | 1 person | Under $150,000 (approx. 400-500% FPL) | Under $150,000 + high OOP costs | | 2 people | Under $150,000 (adjusted for size) | Under $150,000 + high OOP costs | | 3 people | Under $150,000 (adjusted for size) | Under $150,000 + high OOP costs | | 4+ people | Under $150,000 (adjusted for size) | Under $150,000 + high OOP costs | *Notes: Household includes you and dependents. Provide income proof if requested. Exceptions possible.[1][4] ## Insurance Requirements - **Uninsured** or **insured but no coverage for ZELBORAF**: Eligible if income qualifies.[1][2] - **Insured with coverage**: Must pursue other help first (e.g., appeals, co-pay programs). Can't hide/decline coverage. Medicare patients may qualify if costs are unaffordable.[4][6] **Medicare tip**: If on Medicare Part D, check if ZELBORAF is covered; program helps if OOP costs exceed limits or no coverage.[4] ## Step-by-Step Application Process Applying takes **two forms** from you and your doctor. It's free and uses multiple methods.[2][3] 1. **Check eligibility**: Call **(888) 941-3331** (Mon-Fri, 6am-5pm PT) or visit gene.com/patients/patient-foundation.[6] 2. **Complete Patient Consent Form**: Fill out online (English/Spanish), print/sign, or have guardian sign if under 18. Include household size, income, insurance status.[1][2] 3. **Doctor completes Prescriber Foundation Form**: Includes diagnosis (e.g., melanoma BRAF V600E), prescription, shipment choice (home/practice).[1][4] 4. **Submit both forms**: - **Online**: eSubmit at GenentechPatientFoundation.com or My Patient Solutions.[2][3] - **Fax**: (833) 999-4363.[1][2] - **Text photo**: (650) 877-1111.[2] - **Phone start**: (888) 941-3331.[3] 5. **Wait for review**: Processed in **5 business days**.[2] 6. **Get contacted**: You and doctor called with outcome/next steps.[1][2][3] **Tips**: Submit forms together for speed. E-prescribe if possible (query MedVantx/AmeriPharm).[1] ## Timeline and Delivery - **Processing**: 5 business days after both forms received.[2] - **Approval notice**: Phone call to you/doctor.[1][3] - **Delivery**: Shipped free to **your home**, **doctor's office**, or **treatment site** via foundation pharmacy. Options: upfront shipments or product replacement.[1] - **Refills**: Up to **1 year**; reauthorization needed.[1] ## Alternatives if Denied - **Appeal denial**: Ask Foundation Specialist why and resubmit if possible.[6] - **Other Genentech support**: Genentech Access Solutions for co-pay help (866-422-2377).[3] - **State programs**, **patient access networks** (e.g., PAN Foundation), or **generic alternatives** (none for ZELBORAF currently).[6] - **Doctor's sample inventory** or **financial counselor** at clinic. - **No biosimilars** for ZELBORAF.[10] ## Reauthorization Yes, required for refills/continued supply (e.g., annually). Resubmit updated forms.[1] ## Disclaimer This guide is for informational purposes based on publicly available program details as of 2026. Eligibility, rules, and income thresholds can change—always verify with Genentech at (888) 941-3331 or gene.com/patients/patient-foundation. Not medical/financial advice; consult your doctor/insurer. Genentech not liable for application errors.

Program information last verified: March 25, 2026