Zavzpret

Indicated For

acute migraine

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get Zavzpret (zavegepant) at Low or No Cost Zavzpret (zavegepant) is a prescription nasal spray used to treat acute migraine attacks with or without aura in adults. The **Pfizer Patient Assistance Program** offers this medication at low or no cost to eligible uninsured or underinsured patients who meet income and other requirements.[1][2] ## About Zavzpret (zavegepant) **Zavzpret** is an innovative calcitonin gene-related peptide (CGRP) receptor antagonist delivered as a nasal spray. It works by blocking CGRP, a protein that causes blood vessels to dilate and inflammation during migraines, providing fast relief without sedation. Administer one spray into one nostril as needed for migraine symptoms; do not exceed 8 sprays in 24 hours. Common side effects include nausea, vomiting, and nasal discomfort. Always follow your doctor's instructions and consult them for personalized advice. This program helps ensure access for those facing financial barriers.[1] ## Who Qualifies for the Program? The Pfizer Patient Assistance Program is designed for patients struggling to afford their Pfizer medications, like Zavzpret. Key eligibility criteria include: - **Residency**: Must live in the U.S. or U.S. territory with a valid U.S. address (proof of citizenship not required).[2] - **Age and Treatment**: 18 years or older, treated outpatient by a U.S.-licensed healthcare provider.[8] - **Prescription**: Valid prescription for Zavzpret for an FDA-approved use.[2][3] - **Income**: Household income at or below **300% of the Federal Poverty Level (FPL)**, adjusted for family size.[provided] - **Insurance**: Uninsured, underinsured with inadequate coverage, or denied by insurer (after appeal). **Commercially insured patients are not eligible**.[2][3][8] ## Income Eligibility Breakdown Eligibility is based on pre-tax household income not exceeding 300% of the FPL. Use the table below for 2026 guidelines (FPL updates annually; verify current levels at application).[provided] | Household Size | Annual Income Limit (300% FPL) | |----------------|-------------------------------| | 1 (Individual) | $45,180 | | 2 (Couple) | $61,320 | | 3 | $77,460 | | 4 | $93,600 | | +1 Member | Add $16,140 each | **Notes**: Include all household income sources (wages, Social Security, etc.). Provide proof like tax returns, W-2s, or pay stubs.[5][2] Income rules may change; program confirms at enrollment.[1] ## Insurance Requirements - **Uninsured**: Fully eligible if other criteria met.[2] - **Underinsured/Government Insurance**: Eligible if coverage is inadequate (e.g., high copays after prior authorization) or denied (post-appeal). Medicare Part D patients may need to enroll in the Medicare Prescription Payment Plan and attest inability to afford costs.[6][8] - **Commercial Insurance**: Not eligible, even with high deductibles.[2][3] Patients on certain plans may need to exhaust other assistance first.[2] Submit insurance cards (front/back) if applicable.[8] ## Step-by-Step Application Process Applying is straightforward via online, phone, or mail/fax. Multiple methods available.[provided][1] 1. **Check Eligibility**: Visit **www.pfizerrxpathways.com**, use Program Finder, enter "Zavzpret". Follow prompts.[1][2] 2. **Gather Documents**: - Valid Zavzpret prescription. - Proof of income (e.g., 1040 tax pages 1-2, W-2, 2 pay stubs, SSA-1099).[5][2] - Proof of residency (e.g., utility bill).[provided] - Insurance details/denial letter if applicable.[8] 3. **Complete Application**: - **Online (Preferred)**: Use Pfizer PAP Connect for new/enrolled patients. Upload docs, track status.[4][1] - **Phone**: Call (833) 224-2348 for help.[provided] - **Mail/Fax**: Download form from site, send to P.O. Box 66585, St. Louis, MO 63166-6585 or fax 866-470-1748/1-877-548-1734.[5][10] 4. **Healthcare Provider Role**: Doctor completes/sends prescription section.[5] 5. **Sign and Submit**: Patient signs certifications; e-sign if online.[10] Work with your doctor or caregiver. Applications for certain meds may go fully manual if online unavailable.[1] ## Timeline and Delivery - **Processing**: Notification in **2-3 weeks** (sometimes 3 business days via PAP Connect).[1][5][9] - **Approval Notice**: Letter with enrollment term (typically 1 year), Patient ID, refill instructions.[5][4] - **Delivery**: Medication **shipped free to your home** via mail.[provided] - **Reauthorization**: Required annually or per term; reapply before expiration.[provided][10] Track online if using PAP Connect.[4] ## Alternatives if Denied or Ineligible - **Appeal**: Contact program if denied; resubmit updated docs.[1] - **Other Pfizer Options**: Check Pfizer RxPathways for copay savings (commercial insurance) or state programs.[2] - **Government Aid**: Apply to Medicaid, Medicare Extra Help, or state exchanges first if required.[2] - **Manufacturer Hotline**: 1-844-989-7288 (Pfizer Oncology Together, general support).[8] - **No Biosimilars**: None available for Zavzpret.[provided] - **Generic/Other Migraine Meds**: Discuss sumatriptan nasal spray or oral options with your doctor. ## Disclaimer This guide is for informational purposes based on program details as of March 2026. Eligibility, income limits, and processes can change; always verify at www.pfizerrxpathways.com or by calling (833) 224-2348. Pfizer makes final decisions. Not medical advice—consult your healthcare provider. Program provided by Pfizer Inc. and Pfizer Patient Assistance Foundation (separate entities).[5] (Word count: 1028)

Program information last verified: March 30, 2026