Zarxio

Indicated For

neutropenia, chemotherapy-induced neutropenia, stem cell transplant, acute myeloid leukemia

About This Medication

# Novartis Patient Assistance Foundation Patient Guide: How to Get Zarxio (filgrastim-sndz) at Low or No Cost Zarxio (filgrastim-sndz) is a biosimilar medication used to help reduce the risk of infection in patients undergoing chemotherapy by boosting white blood cell production. The **Novartis Patient Assistance Foundation (NPAF)** offers this drug at low or no cost to eligible uninsured or underinsured U.S. residents who meet specific income guidelines.[1][2][3] ## About Zarxio (filgrastim-sndz) **Zarxio** is an injectable prescription medicine that acts like a growth factor for white blood cells (neutrophils). It's commonly prescribed for: - Patients with cancer receiving strong chemotherapy that lowers white blood cell counts. - People with severe chronic neutropenia (low neutrophil counts). - Those undergoing bone marrow transplants or facing acute radiation exposure. As a biosimilar to Neupogen (filgrastim), Zarxio provides the same benefits at potentially lower costs. It's administered via subcutaneous injection, often daily, under your doctor's guidance. Always follow your healthcare provider's instructions, and discuss side effects like bone pain, fever, or spleen issues.[1][6] ## Who Qualifies for the NPAF Program? To qualify for free or low-cost Zarxio through NPAF, you must: - Live in the United States or a U.S. territory.[2][6] - Have limited or no prescription insurance coverage (uninsured or underinsured).[1][2][7] - Meet income guidelines based on **400% of the Federal Poverty Level (FPL)**, which varies by household size and product.[program data][6] - Have a valid prescription from a licensed U.S. healthcare provider for outpatient treatment.[2][4] The program is for patients unable to afford their medications despite other resources. It's not for those with full insurance coverage.[1][3] ## Income Eligibility Breakdown NPAF uses **400% of the FPL** as the threshold. Eligibility varies by household size—check exact limits at www.PAP.Novartis.com, as they update annually. Here's a sample table based on 2026 FPL guidelines (approximate; confirm current figures): | Household Size | Max Annual Income (400% FPL) | |----------------|------------------------------| | 1 (Individual) | $60,240 | | 2 (Couple) | $81,760 | | 3 | $103,280 | | 4 | $124,800 | | +1 per person | +$21,520 | **Notes**: Provide proof like the first 2 pages of your 1040 tax return. Guidelines may differ slightly by product; contact NPAF if not required to file taxes.[1][2][6] Income includes all household earnings. ## Insurance Requirements - **Uninsured patients**: Fully eligible if other criteria met.[7] - **Underinsured**: Accepted if insurance doesn't cover Zarxio fully (e.g., high copays, denials). Submit front/back copies of all insurance cards (primary, secondary, Rx).[1][2] - **Medicare patients**: Often ineligible if Part D covers the drug; provide denial or proof of coverage gaps.[1] - If prior authorization (PA) is needed, include PA approval/denial.[1][4] NPAF reviews insurance status carefully—incomplete info delays processing.[3] ## Step-by-Step Application Process 1. **Check Eligibility**: Visit www.PAP.Novartis.com to confirm Zarxio coverage and your income.[2][3][6] 2. **Download Form**: Get the application from the site or call 1-800-277-2254.[3][4] 3. **Gather Documents**: - Proof of income (e.g., 1040 tax return first 2 pages, W-2, pay stubs).[1][6][7] - Proof of residency (e.g., utility bill).[program data] - Prescription for Zarxio.[4][7] - Insurance cards (front/back) or denial letters.[1][2] 4. **Complete Sections**: Patient fills personal/income/insurance; doctor completes prescriber section, signs, and provides Rx.[2][4][9] 5. **Sign Authorizations**: Patient signs to allow info sharing.[1][9] 6. **Submit**: Fax to 1-855-817-2711 or mail to NPAF, PO Box 2529, Columbus, OH 43216 (or current address).[1][6][9] Both patient and HCP sections can be faxed together. **Tip**: Double-check completeness—missing info causes delays/denials.[1][2][4] ## Timeline and Delivery - **Processing**: 2-4 weeks (up to 4 weeks per NPAF).[3][6][program data] - You'll get a letter (and text if opted in) with status or next steps.[3] - If approved, medication ships free to your home or doctor's office.[program data] - **Reauthorization**: Required annually or per supply limit; resubmit updated docs.[8][program data] Call 1-800-277-2254 (Mon-Fri, ~8am-8pm ET) for status.[4][6][8] ## Alternatives if Denied - **Appeal**: Contact NPAF for reasons and resubmit missing info.[3][5] - **Other Programs**: Check PANO (oncology), co-pay cards, or state assistance.[10] - **Generic/Biosimilar Options**: No listed alternatives, but discuss with doctor.[program data] - **RxHope, Simplefill, or NeedyMeds**: Free search tools for other PAPs.[6][10] - **Manufacturer Rep**: Ask Sandoz/Novartis for samples or bridges.[program data] ## Important Disclaimer This guide is for informational purposes only and based on available program data as of 2026. Eligibility, guidelines, and processes can change—always verify at www.PAP.Novartis.com or by calling NPAF. Not medical/financial advice; consult your doctor and advisor. NPAF decisions are final; no guarantees of approval. Medication use per prescriber.[1][2][3]

Program information last verified: March 30, 2026