ZALTRAP

Indicated For

metastatic colorectal cancer

About This Medication

# Sanofi Patient Connection Patient Guide: How to Get ZALTRAP at Low or No Cost ZALTRAP (ziv-aflibercept) is a prescription medication used to treat metastatic colorectal cancer (mCRC) that has progressed after an oxaliplatin-containing regimen, typically in combination with FOLFIRI (fluorouracil, leucovorin, and irinotecan). The **Sanofi Patient Connection** program offers this and other Sanofi medications **at no cost** to eligible uninsured or underinsured patients struggling with expenses.[1][3][9] ## About ZALTRAP **ZALTRAP** is a vascular endothelial growth factor (VEGF) inhibitor delivered as an intravenous infusion. It works by blocking proteins that promote blood vessel growth in tumors, helping to slow cancer progression in patients with mCRC resistant to prior treatments.[7][9] Administered by a healthcare professional (HCP) in a clinical setting, it requires careful monitoring due to potential serious side effects like bleeding, high blood pressure, or impaired wound healing. Always discuss risks and benefits with your doctor.[9] This guide explains how to access ZALTRAP through Sanofi Patient Connection's **Patient Assistance Connection**—a free program providing medications to those meeting strict financial and residency criteria. No purchase is required, and it's designed for patients facing barriers to care.[1][2][3] ## Who Qualifies? Eligibility focuses on financial need, residency, insurance status, and medical necessity. Key requirements include: - **U.S. residency**: You must live in the U.S. or U.S. territories. - **Under HCP care**: A licensed U.S. healthcare provider must prescribe and oversee your treatment.[1][2] - **Income limits**: Household income at or below **400% of the Federal Poverty Level (FPL)**. - **Insurance status**: Uninsured or underinsured; **not eligible** if enrolled in Medicare, Medicaid, or similar government programs (Medicaid denial letter required if applicable).[1][3] - **No alternatives**: You've exhausted other assistance options where required.[3] ## Income Eligibility Breakdown Income thresholds are based on **≤400% FPL** for your household size. Use recent pay stubs, tax returns, or benefit statements for proof. Here's a simplified table (based on 2026 FPL guidelines; check sanofipatientconnection.com for exact current figures): | Household Size | Max Annual Income (400% FPL) | |----------------|------------------------------| | 1 (Individual) | $60,000 | | 2 (Couple) | $81,000 | | 3 | $102,000 | | 4 | $122,400 | | +1 per member | +$20,400 | **Notes**: Medicaid-eligible applicants need a denial letter. Income includes all household sources.[1][3] Visit the program site for a financial eligibility tool.[3] ## Insurance Requirements The program is for **uninsured or underinsured** patients only. You **cannot** participate if you have: - Medicare (Part D enrollment limits aid to calendar year end).[1][2][6] - Medicaid, VA, Tricare, or state programs. - Employer or commercial insurance covering the drug fully. Underinsured patients with high copays/deductibles may qualify if income criteria are met and no other aid applies. Provide proof like Explanation of Benefits (EOB).[1] ## Step-by-Step Application Process Applications are straightforward but require your doctor's involvement. **Multiple methods** available: download online, call 1-888-847-4877, or request mailing.[6][8] 1. **Download or get the form**: Visit sanofipatientconnection.com, select your state, and print pages 2-3.[1][3][8] 2. **Fill patient section (Page 2)**: Enter personal details, sign HIPAA/income verification authorizations. Attach **proof of income** (e.g., tax return, W-2), **residency** (utility bill, lease), and Medicaid denial if needed.[1][2] 3. **Doctor completes Page 3**: Your HCP verifies diagnosis, prescribes ZALTRAP, signs/dates.[1][6] 4. **Submit**: HCP faxes to **1-888-847-1797** or mails to **Sanofi Patient Connection, PO Box 222138, Charlotte, NC 28222-2138**. No medical records needed.[1][2][6] 5. **Avoid delays**: Ensure completeness—missing info triggers follow-up.[1][6] ## Timeline and Delivery - **Processing**: 5-7 business days for complete apps; longer if incomplete.[2][5][6] - **Approval notice**: Letters to you, HCP, and insurer (if applicable) within 10 business days.[2][5] - **Enrollment**: Up to **12 months**; Medicare Part D through year-end.[1][2][6] - **Delivery**: Medication **shipped free to your doctor's office** in ~5-7 business days post-approval—not directly to you.[2] - **Pick up**: Coordinate with your HCP for infusion scheduling.[1] ## Alternatives if Denied - **Reapply**: Fix issues (e.g., update income) and resubmit.[6] - **State programs**: Check Minnesota Safety Net or Maine insulin aid for parallels (ZALTRAP not specified).[4][5] - **Other resources**: Patient Advocate Foundation (1-800-532-5274) or general copay cards.[7] - **No biosimilars** available for ZALTRAP currently.[program data] ## Reauthorization **Reauthorization required** annually. Reapply before 12 months end (or calendar end for Medicare). Same process; updated income proof needed.[1][6] ## Important Disclaimer This guide is for informational purposes based on publicly available program details as of latest updates. Eligibility, guidelines, and FPL change—**always verify at sanofipatientconnection.com or call 1-888-847-4877**. Sanofi may update terms. Not legal/medical advice; consult your doctor. Program not valid with government insurance. Third-party fees not affiliated.[1][3][6]

Program information last verified: March 30, 2026