XYWAV

Indicated For

narcolepsy, idiopathic hypersomnia

About This Medication

# JazzCares Patient Assistance Program Patient Guide: How to Get XYWAV at Low or No Cost XYWAV (calcium, magnesium, potassium, and sodium oxybates) is a prescription medication used to treat cataplexy or excessive daytime sleepiness in patients 7 years and older with narcolepsy, and idiopathic hypersomnia in adults. The **JazzCares Patient Assistance Program** from **Jazz Pharmaceuticals** helps eligible patients who are uninsured, underinsured, or facing financial hardship receive XYWAV at no cost. ## About XYWAV **XYWAV** is an oxybate medication taken at night to improve sleep and reduce symptoms of narcolepsy, such as sudden muscle weakness (cataplexy) and excessive daytime sleepiness (EDS). Unlike older oxybate treatments, XYWAV has less sodium, which may benefit heart health. Due to risks like central nervous system depression and potential for misuse, XYWAV is only available through the **XYWAV and XYREM REMS** program—a restricted distribution system requiring enrollment by you and your doctor. A certified pharmacy ships the medication directly to your home. JazzCares provides comprehensive support, including **Nurse Case Managers**, 24/7 pharmacists, and financial experts to guide you from diagnosis to ongoing treatment. ## Who Qualifies for the Program? The program targets patients with **low income levels** who are **uninsured, underinsured, Medicare/Medicaid patients, or those without coverage for XYWAV**, plus additional financial needs. You must reside in the US, Puerto Rico, or other US territories. Specific income thresholds are not publicly detailed but align with low-income guidelines; eligibility is determined case-by-case based on proof of financial hardship. | Household Size | Income Threshold | Notes | |---------------|------------------|-------| | Individual | Low-income level | Assessed via proof of income; exact FPL % not specified | | Couple | Low-income level | Additional financial needs considered | | Family of 3 | Low-income level | Uninsured/underinsured prioritized | | Family of 4+ | Low-income level | Case-by-case review | *Table based on program notes for low-income, needs-based eligibility.* ## Income Eligibility Breakdown Eligibility focuses on demonstrating **financial need** rather than strict federal poverty level (FPL) cutoffs. Submit recent tax returns, pay stubs, or benefit statements showing low income. Programs like this often use 400% FPL or less, but JazzCares reviews holistically, factoring in out-of-pocket costs, household size, and insurance gaps. If you're on Medicare Part D or Medicaid, you may still qualify if XYWAV isn't covered. ## Insurance Requirements - **Uninsured**: Fully eligible if income-qualified. - **Underinsured**: Coverage exists but doesn't cover XYWAV or leaves high costs. - **Medicare/Medicaid**: Eligible if no coverage for XYWAV; JazzCares verifies benefits. - **Commercial insurance**: May qualify for this program if denied coverage, but check **XYWAV Coupon** ($5 copay for >99% eligible) or **Bridge Program** (up to 120 days free while awaiting approval) first. All patients must enroll in the **XYWAV and XYREM REMS**. ## Step-by-Step Application Process 1. **Discuss with Your Doctor**: Confirm XYWAV prescription. Doctor must certify in REMS and complete **XYWAV and XYREM REMS Patient Enrollment Form** and **XYWAV Prescription Form**. 2. **Enroll in JazzCares**: Visit [jazzcares.com/xywav](https://www.jazzcares.com/patients/xywav/) or call **(866) 997-3688** to start. Highly recommend **JazzCares Patient Authorization Form** for full support. 3. **Gather Documents**: - **Proof of income** (tax returns, W-2s, pay stubs). - **Proof of residency** (utility bill, lease). - **Proof of insurance status** (insurance card, denial letter, or uninsured statement). 4. **Submit Application**: Online at jazzcares.com/xywav, download/print/mail to JazzCares Patient Assistance Program, PO Box 66589, St. Paul, MN, or fax/call (866) 997-3688. Multiple methods available. 5. **JazzCares Review**: Team verifies eligibility, insurance, and REMS enrollment. A Nurse Case Manager contacts you. 6. **Approval Notification**: If approved, medication ships from certified pharmacy. ## Timeline and Delivery Processing time varies (not specified; typically 1-2 weeks). While waiting: - **Quick Start Voucher/Bridge Program**: Up to 120 days free if insurance delay ≥3 days or therapy interruption risk. Delivery: **Shipped directly to your home** via certified pharmacy. 24/7 pharmacist support included. **Reauthorization required** annually or upon changes. ## Alternatives if Denied - **XYWAV Coupon Program**: $5 per prescription for eligible commercially insured. - **Bridge Program**: Free supply during appeals. - **Prior Authorization (PA) Appeal**: Doctor submits PA via CoverMyMeds or plan portal with diagnosis, meds history, Epworth Scale. - **Other Assistance**: Contact JazzCares at 1-833-533-5299 (Mon-Fri 8am-8pm ET) for copay cards or state programs. - **Generic/Biosimilars**: None available. If denied, reapply with updated documents or explore patient access foundations. ## Important Safety and Next Steps XYWAV has serious risks; follow REMS guidelines. Track symptoms with myWAV app. JazzCares Nurse Educators offer mentor programs. **Disclaimer**: This guide is for informational purposes only and based on available program details as of last update. Eligibility, terms, and availability can change. Jazz Pharmaceuticals reserves the right to modify/terminate anytime. Consult your doctor and JazzCares directly for personalized advice. Not a substitute for medical or legal counsel. Enroll in REMS; report side effects to FDA at 1-800-FDA-1088.

Program information last verified: March 30, 2026