Xyrem

Indicated For

Narcolepsy with cataplexy, Excessive daytime sleepiness

About This Medication

# JazzCares Patient Assistance Program Patient Guide: How to Get Xyrem at Low or No Cost Xyrem (sodium oxybate) is a prescription medication used to treat cataplexy and excessive daytime sleepiness in patients with narcolepsy. The **JazzCares Patient Assistance Program** from **Jazz Pharmaceuticals** helps eligible patients—especially those who are uninsured, underinsured, or facing financial hardship—access Xyrem at low or no cost through free medication, support services, and more.[1][7] ## About Xyrem and Why Assistance Matters Xyrem is a controlled substance taken at night to improve nighttime sleep and reduce daytime symptoms of narcolepsy, like sudden muscle weakness (cataplexy) or overwhelming sleepiness. Because it's only available through a restricted program called the **XYREM and XYWAV REMS** (Risk Evaluation and Mitigation Strategy), all prescriptions go through a certified pharmacy with 24/7 pharmacist support.[3][5][6] This ensures safe use but can make access challenging without insurance. High costs and insurance hurdles often prevent patients from starting or staying on treatment. JazzCares steps in with **free medication** for eligible uninsured or underinsured patients, a **Bridge Program** for coverage gaps (up to 4 months free), and a **Quick Start Voucher** for a free 1-month supply during delays.[1][2] Other options like a **Coupon Program** (as low as $35 per 30-day fill) are for commercially insured patients, but the Patient Assistance Program focuses on those without adequate coverage.[1][2][4] ## Who Qualifies for the Program? The program targets patients experiencing **financial hardship**, including the uninsured, underinsured, Medicare, Medicaid, or those whose insurance doesn't cover Xyrem.[1][7] You must be enrolled in the **XYREM REMS** program, which requires your doctor to certify and submit enrollment forms.[3][5][6] ### Income Eligibility Breakdown Income requirements are **not publicly disclosed**—it's a needs-based evaluation. Jazz Pharmaceuticals reviews proof of income case-by-case to determine eligibility for free medication.[1] Here's a summary: | Household Size | Threshold | Notes | |---------------|-----------|-------| | Individual | Not specified | Needs-based; financial hardship assessed | | Couple | Not specified | Proof of income required for all | | Family of 3 | Not specified | Uninsured/underinsured prioritized | | Family of 4+ | Not specified | No fixed FPL percentage listed | Contact the program for a personalized assessment via phone or application.[1] ## Insurance Requirements This program is designed for: - **Uninsured patients**: Eligible for free treatment.[1][7] - **Underinsured**: If insurance doesn't cover Xyrem or costs are unaffordable.[1] - **Medicare/Medicaid patients**: Supported, unlike some coupons that exclude government programs.[1][4] Commercial insurance patients may qualify for the Coupon Program ($35 copay cap, annual max benefit) instead, but Patient Assistance is for broader financial need.[2][4] A **JazzCares Nurse Case Manager** helps navigate coverage verification.[5] ## Step-by-Step Application Process 1. **Talk to Your Doctor**: Ensure you're enrolled in XYREM REMS (one-time forms: Prescriber Enrollment, Patient Enrollment, Prescription Form). Your doctor prescribes Xyrem.[3][6] 2. **Gather Documents**: - Completed **JazzCares Patient Authorization Form** (download from jazzcares.com).[3] - **Proof of income** (pay stubs, tax returns). - **Insurance information** (cards, denial letters). - **Physician prescription**.[1] 3. **Apply**: Multiple methods—call **(866) 997-3688**, visit https://jazzcares.com/patients/xyrem/, or use the certified pharmacy. Sign up for refill reminders too.[1] 4. **Submit and Wait**: Processing takes **2-3 days**.[1] 5. **Approval**: If approved, medication ships **overnight to your home**.[1] A nurse manager assesses needs and provides ongoing support.[1][5] **Reauthorization is required** periodically to confirm ongoing eligibility.[1] ## Timeline and Delivery - **Application to Decision**: 2-3 days.[1] - **Delivery**: Overnight to home via certified pharmacy.[1] - **Refills**: Easy online scheduling with email/text reminders. 24/7 pharmacist access.[1] - **Bridge/Quick Start**: Faster for coverage delays (1-4 months free).[1][2] Expect your **dedicated Nurse Case Manager** to guide you, addressing challenges and motivation.[1] ## Alternatives if Denied or Additional Options - **Bridge Program**: Up to 4 months free while awaiting insurance approval (not for Medicare/Medicaid).[1][2] - **Quick Start Voucher**: Free 1-month supply for delays >10 days or therapy interruption risk.[1][2] - **Coupon Program**: $35 per fill for commercial insurance (excludes government programs).[2][4] - **Other Support**: myWAV app, Mentor Program, nurse educators.[5] - **Appeal or Reapply**: Contact (866) 997-3688 if denied; provide updated financials.[1] - **Generic/Biosimilars**: None currently available.[1] If ineligible, ask your doctor about prior authorizations via CoverMyMeds or health portals.[6] ## Important Disclaimer This guide is for informational purposes based on publicly available program details as of 2026. Eligibility, benefits, and terms can change; Jazz reserves the right to modify or end the program.[1][2][6] Always verify with JazzCares at (866) 997-3688 or jazzcares.com. Not medical advice—consult your healthcare provider. Xyrem has serious risks (CNS depression, abuse potential); follow REMS strictly.[6] Word count: 1028.

Program information last verified: March 30, 2026