Xyosted

Indicated For

testosterone deficiency, hypogonadism

About This Medication

# XYOSTED Patient Guide: How to Get XYOSTED at Low or No Cost Xyosted (testosterone enanthate) is a once-weekly subcutaneous auto-injector used to treat low testosterone levels in adult men. This guide explains the XYOSTED Co-pay Assistance Program and XYOSTED4YOU Cash Program, which help eligible patients reduce costs to as low as $25 per prescription or $199 per month.[1][3][5] ## About XYOSTED **Xyosted** is a brand-name prescription medication for testosterone replacement therapy (TRT) in adult males with hypogonadism, a condition where the body doesn't produce enough testosterone. It comes as a prefilled auto-injector pen administered under the skin once a week, making it convenient compared to other injections.[4][6][9] Common symptoms of low testosterone include fatigue, low energy, decreased muscle mass, mood changes, and low libido. Your doctor diagnoses this with blood tests showing morning testosterone levels below the normal range, plus persistent symptoms.[2][9] Xyosted is not for everyone—it's for men 18+ confirmed to have low testosterone, with other causes ruled out. Always follow your doctor's instructions, as misuse can cause serious side effects like high blood pressure, heart risks, or prostate issues. Talk to your healthcare provider about benefits and risks.[9] ## Who Qualifies for Assistance? XYOSTED offers **two main programs** based on your insurance status: 1. **Co-pay Assistance Program** (for commercially insured patients): Reduces your out-of-pocket cost to **$25 per fill** for up to **13 fills per year** (about 1 year of weekly doses). Maximum benefit is $125 per prescription.[1][2][3] 2. **XYOSTED4YOU Cash Program** (for uninsured or when insurance doesn't cover XYOSTED): Buy at a flat **$199 per month** through partnered specialty pharmacies. No insurance needed.[3][4][5] **Key eligibility for both**: - 18 years or older. - Valid U.S. prescription for XYOSTED. - U.S. resident with valid U.S. shipping address.[1][5] **Important exclusions**: Neither program works with government programs like Medicare, Medicaid, Tricare, or state assistance. Co-pay card is for commercial insurance only; cash program excludes any insurance coverage.[1][2][3][5] ## Income Eligibility These programs **do not use income thresholds** like many patient assistance programs. Instead, eligibility focuses on age, prescription, residency, and insurance type (commercial only for co-pay; none for cash).[1][5] No financial documentation or FPL (Federal Poverty Level) checks are required, making it accessible for a wide range of patients.[1][3] | Household Size | Income Threshold | Notes | |---------------|------------------|-------| | Individual | None | No income verification needed.[1][5] | | Couple | None | Focus on insurance status.[3] | | Family of 3 | None | U.S. residency required.[5] | | Family of 4 | None | Government insurance ineligible.[2] | This flat-rate approach simplifies access compared to income-based PAPs.[4] ## Insurance Requirements - **Commercial insurance**: Use the Co-pay Card for $25 fills. Not valid if your plan is government-funded.[1][2] - **No insurance or non-covering insurance**: Use XYOSTED4YOU at $199/month.[5] - **Medicare/Medicaid/Tricare**: Ineligible for these programs. Explore other options like GoodRx discounts or pharmacy savings (up to 80% off), but check Medicare coverage separately.[7][8] Your insurance may require **prior authorization (PA)** for XYOSTED, needing lab proof of low testosterone, symptoms, and why other treatments (like gels or IM injections) aren't suitable.[9] Ask your doctor or insurer about PA. ## Step-by-Step Application Process ### For Co-pay Assistance: 1. Visit **www.xyosted.com/co-pay-support** or ask your doctor/pharmacist for the Co-pay Card.[1] 2. Activate the card online or by phone (details on site).[1] 3. Present the card at a pharmacy when filling your XYOSTED prescription. 4. Pay **$25** per fill (up to 13/year).[1][3] ### For XYOSTED4YOU Cash Program: 1. Confirm eligibility: 18+, prescription, no government insurance.[5] 2. Call **1-844-XYOSTED (1-844-996-7833)** or visit **www.xyosted.com/xyosted4you**.[4][5] 3. Provide your prescription to a partnered specialty pharmacy. 4. Purchase at **$199/month**; medication ships to your U.S. address (shipping fees may apply).[5] Your doctor may need to submit labs/chart notes for pharmacy or insurance approval: two low morning testosterone tests, symptoms, and treatment history.[2] No formal application form—it's card-based or cash purchase. ## Timeline and Delivery - **Co-pay Card**: Instant at pharmacy once activated. Fills take standard pharmacy time (same day or next).[1] - **XYOSTED4YOU**: Processing via specialty pharmacy; expect **a few days to 1 week** for shipping after prescription verification. Limited to 30-day supply per fill.[5][9] Delivery is to your U.S. address via specialty pharmacies. Opt into **X-Factor Program** for support reminders and tips.[1] Free auto-injector disposal available.[2] ## Alternatives if Denied or Ineligible - **Discount cards**: GoodRx or Optum Perks for up to 80% off retail.[7][8] - **90-day supply**: Ask insurance/pharmacy for cost savings.[6] - **Generic testosterone**: Like testosterone cypionate injections (cheaper alternative for TRT).[4][6] - **Other TRT**: Topical gels/patches if allowed by insurance.[9] - **Manufacturer resources**: Call 1-844-996-7833 for guidance.[4] If denied co-pay (e.g., government insurance), switch to XYOSTED4YOU if eligible.[3] ## Disclaimer This guide is for informational purposes only and based on publicly available program details as of 2026. Programs can change; Halozyme (manufacturer) reserves the right to modify/revoke offers.[2] Not medical advice—consult your doctor for treatment suitability. Eligibility not guaranteed. Void where prohibited. For latest info, visit www.xyosted.com or call 1-844-XYOSTED.[1][5] (Word count: 1028)

Program information last verified: March 30, 2026