XTANDI

Astellas Patient Assistance Program Patient Guide: How to Get XTANDI (enzalutamide) at Low or No Cost

About XTANDI (enzalutamide)

XTANDI is a prescription medication used to treat certain types of prostate cancer, including metastatic castration-resistant prostate cancer (mCRPC), metastatic castration-sensitive prostate cancer (mCSPC), and non-metastatic castration-sensitive prostate cancer (nmCSPC) with high-risk biochemical recurrence. It works by blocking the action of male hormones (androgens) that can promote prostate cancer growth, helping to slow disease progression and improve quality of life for many patients[1][3].

XTANDI is taken as oral capsules, typically 160 mg once daily. Common side effects include fatigue, diarrhea, hot flashes, and muscle pain, but your doctor will monitor you closely. Always follow your healthcare provider's instructions and report any concerns promptly.

Who Qualifies for the Astellas Patient Assistance Program?

The Astellas Patient Assistance Program (PAP) provides XTANDI at no cost to eligible uninsured patients facing financial hardship. This program is a lifeline for those without prescription drug coverage who need this important therapy[1][3][4].

Key eligibility criteria include:

• Being uninsured (no prescription drug insurance, including no commercial, Medicare Part D, Medicaid, or other government programs)[3][8].
• Having a verifiable shipping address in the United States[3].
• Prescribed XTANDI for an FDA-approved indication[3].
• Meeting financial eligibility requirements, determined on a patient-specific basis (no fixed income thresholds like Federal Poverty Level percentages are publicly specified; income is reviewed individually)[3].

Note: This program is specifically for uninsured patients. If you have commercial insurance, explore the separate XTANDI Patient Savings Program for copay assistance (up to $7,000 per year). Medicare Part D patients are generally covered for XTANDI, with potential affordability improvements in 2026[1][7][8].

Income Eligibility Breakdown

Unlike many programs with strict Federal Poverty Level (FPL) cutoffs, the Astellas PAP assesses financial need case-by-case. There are no published fixed thresholds for individuals, couples, or families. Factors likely considered include household income, assets, medical expenses, and overall financial situation[3].

Here's a general overview based on similar programs (for reference only; call to confirm your situation):

Important: These are illustrative estimates. Actual eligibility is determined individually—no automatic qualifiers. Uninsured status is primary[1][3].

Insurance Requirements

You must be uninsured with no prescription drug insurance to qualify. This means:

• No commercial insurance (PPO, HMO, COBRA).
• No Medicare Part D, Medicaid, Medigap, VA, TRICARE, or other government coverage[3][8].

If you gain insurance later, notify the program immediately, as it may affect eligibility[5]. Programs like XTANDI Quick Start or copay cards exist for insured patients[7][8].

Step-by-Step Application Process

Applying is straightforward and done by phone—no online form or mailed application specified[1][3].

1. Gather Your Information: Prepare your full name, shipping address, doctor's name/contact, prescription details, proof of income (e.g., tax returns, pay stubs), and proof of no insurance (e.g., denial letter).

2. Call XTANDI Support Solutions: Dial 1-855-8XTANDI (1-855-898-2634) Monday-Friday during business hours. Speak to a dedicated access specialist[1][2][3].

3. Discuss Eligibility: The team will review your situation over the phone, ask about finances, insurance, and prescription. They confirm eligibility quickly[3].

4. Submit Prescription and Documents: Your doctor may need to provide a prescription. Additional docs (income proof, no-insurance verification) may be requested anytime[5].

5. Approval Notification: If approved, you'll receive confirmation (possibly via mail/email/text if opted in)[5].

6. Receive Medication: XTANDI is shipped directly to your home at no cost[1].

Tip: Have your doctor call too—they can get fast eligibility confirmation[3].

Timeline and Delivery

• Processing Time: Often quick—eligibility can be confirmed during the call, with shipment soon after[3]. Exact timelines vary.
• Delivery: Free shipping to your U.S. address. Track via the support line.
• Supply Duration: Typically covers ongoing needs; reauthorization may apply (see FAQ).

Alternatives if Denied or Ineligible

• Commercial Insurance: XTANDI Patient Savings Program—pay as little as $0 copay, up to $7,000/year max[1][8][9]. Activate at activatethecard.com/xtandi.
• Medicare Part D: 100% coverage reported; explore 2026 changes for lower costs. Other resources available[1][4].
• Other Programs: PAN Foundation for prostate cancer (up to $2,000/year for Medicare)[7]. NeedyMeds, RxAssist, or state programs.
• Quick Start: For new commercially insured patients[8].
• Appeal: Contact support to discuss denial reasons and resubmit[5].

Disclaimer

This guide is for informational purposes only and based on publicly available data as of 2026. Program details can change; always verify with XTANDI Support Solutions at 1-855-898-2634. Astellas reserves the right to amend eligibility, revoke benefits, or limit assistance (e.g., for accumulator programs). Not valid where prohibited by law. Consult your doctor for medical advice. Assistance not for government-insured patients[1][3][5][8]. (Word count: 1028)