XHANCE

XHANCE Patient Guide: How to Get XHANCE at Low or No Cost

XHANCE (fluticasone propionate) is a prescription nasal spray used to treat chronic rhinosinusitis with or without nasal polyps in adults, helping reduce inflammation and symptoms like nasal congestion and sinus pressure.[3][5] This guide explains the XHANCE Copay Program offered by Paratek Pharmaceuticals, Inc., which allows eligible commercially insured patients to pay as little as $0 out-of-pocket at participating retail pharmacies using a copay card.[1][2][5]

About XHANCE

XHANCE is an exhalation delivery system nasal spray containing fluticasone propionate, a corticosteroid that targets sinus inflammation directly.[3][5] It's FDA-approved for adults with chronic rhinosinusitis (CRS), including those with nasal polyps (CRSwNP) and without (CRSsNP).[5][6]

Key benefits:

• Reduces nasal blockage, congestion, and facial pain/pressure.
• Used twice daily: 1-2 sprays per nostril as prescribed.[4][5]
• For best results, use regularly and refill monthly or as directed.[5]

Important warnings: Do not use if allergic to fluticasone propionate. Tell your doctor about medical conditions, recent oral steroid use (risk of adrenal issues), infections, glaucoma, or cataracts. Common side effects include nosebleeds, headache, and nasal sores.[3]

XHANCE is not known to be safe/effective in children under 18.[3]

Who Qualifies for the XHANCE Copay Program?

This is a copay assistance program, not free medication for uninsured patients. It's designed for commercially insured patients (private insurance, not government programs).[1][2][3]

Eligibility criteria:

• 18 years or older.[2]
• Resident of the US (including Puerto Rico).[2]
• Valid prescription for XHANCE.[2]
• Commercial prescription insurance covering XHANCE.[1][3]
• Not enrolled in government programs like Medicare, Medicaid, TRICARE, or other federal/state plans.[1][2][3]
• Federal Employees Health Benefits (FEP) or Health Care Exchange (HIX) plans are eligible.[3]
• Not paying cash (uninsured).[3]

Income eligibility: No specific income thresholds; eligibility is based on insurance type, not income.[1][3] Uninsured or government-insured patients do not qualify for this copay card.[2]

Income Eligibility Breakdown

The program has no income limits. Here's a summary:

Data from program terms.[1][3]

Insurance Requirements

Must have commercial insurance that covers XHANCE. Government programs (Medicare, Medicaid, etc.) are excluded.[1][2][3] Pharmacists submit claims to your primary insurer first, then use the copay card as secondary payer via specific BIN/PCN/GRP/ID.[2]

Medicare patients: Not eligible for copay card. Check your plan for coverage; prior authorization may be needed.[10] Consider 90-day supplies or mail-order for savings.[10]

No insurance? This program doesn't apply. Explore general patient assistance via Paratek (call 833-942-6231) or sites like RxAssist, NeedyMeds.[7][10]

Step-by-Step Application

No formal application or enrollment form needed—it's instant via copay card.[1][4]

1. Get prescribed XHANCE by your doctor for CRS.[5]
2. Download or print the copay card from xhance.com or xhancehcp.com.[1][2][4]
   • BIN: 610852, PCN: 2001, GRP: 77770254, ID: 11412486564.[2]
3. Present card at a participating retail pharmacy with your prescription.[1][2]
4. Pharmacy processes: Submits to your commercial insurer first, then copay program for balance (as low as $0).[2]
5. Questions? Call 1-833-XHANCE1 (1-833-942-6231).[1][10]

Quantity limits: Maximum benefits per fill and annual max apply. Patient cost-share may affect savings.[1][2][3]

Timeline and Delivery

Instant savings at pharmacy—no processing wait.[1] Pick up XHANCE same-day if in stock. Refill monthly or as prescribed.[5]

Delivery options: Retail pharmacy only; no mail specified for copay card. For convenience, ask about 90-day mail-order through your insurer.[10]

Refills: Use card each time. Program valid through calendar year limits.[2]

Alternatives if Denied or Ineligible

• Government insurance: Use plan coverage; appeal denials or seek prior auth.[10]
• Uninsured/low-income: Contact Paratek at 833-942-6231 for potential patient assistance (details limited; may cover other drugs like Nuzyra).[7][10]
• General resources: Medicine Assistance Tool, NeedyMeds, RxAssist.[10]
• Savings tips: 90-day supply, mail-order pharmacy, generic alternatives (none specified; fluticasone generics exist but XHANCE uses unique delivery).[10]
• Biosimilars: None listed for XHANCE.[ ]

Shop around pharmacies for best pricing if cash-paying.

Disclaimer

This guide is for informational purposes based on available program details as of 2026. Terms can change; Paratek reserves right to amend/revoke.[1][2] Not medical/financial advice. Consult your doctor, pharmacist, or insurer. Eligibility not guaranteed. Visit xhance.com or call 1-833-XHANCE1 for latest info. Program good only at participating US pharmacies.[2] (Word count: 942)