Xacduro

Indicated For

Hospital-acquired bacterial pneumonia (HABP), Ventilator-associated bacterial pneumonia (VABP) caused by Acinetobacter baumannii

About This Medication

# No Patient Assistance Program (PAP) Identified for Xacduro: Access Guide for Sulbactam Durlobactam Xacduro (sulbactam durlobactam) currently has **no dedicated manufacturer patient assistance program (PAP)** from Menarini Group, meaning there is no standard program offering the drug at low or no cost based on income eligibility.[1] This guide explains what this means for patients, details the drug's use, explores alternative cost-saving options like Medicare support, and provides steps for accessing affordable care.[1][2] ## About Xacduro (Sulbactam Durlobactam) **Xacduro** is an intravenous antibiotic co-packaged product (sulbactam for injection and durlobactam for injection) approved for treating hospital-acquired and ventilator-associated bacterial pneumonia (HABP/VABP) in adults caused by susceptible isolates of *Acinetobacter baumannii-calcoaceticus* complex, including multidrug-resistant strains.[1] It is the first and only treatment specifically targeting these infections, showing non-inferiority to colistin for 28-day all-cause mortality and higher clinical cure rates.[1] Administered in hospitals, Xacduro has a favorable safety profile but is reserved for serious cases where other antibiotics may fail.[1] As a hospital-administered drug, costs are often covered under inpatient stays, but out-of-pocket expenses can arise for uninsured patients or those with high deductibles. Without a PAP, patients must rely on insurance, government programs, or discounts.[1][2] ## Who Qualifies for Assistance? Since **no PAP is identified** for Xacduro, there are no specific income thresholds, required documents, or application processes from the manufacturer.[1] Menarini Group does not list a program on official resources, and searches confirm 'No PAP identified.'[1][3] However, many patients may qualify for broader assistance: - **Uninsured or low-income**: Explore state programs or general charity care. - **Medicare patients**: Part D coverage, Extra Help, or the Medicare Prescription Payment Plan (spreads costs up to $2,000 out-of-pocket cap in 2025).[2] - **Commercial insurance**: Co-pay cards from similar programs (though not available for Xacduro) or GoodRx discounts.[2] ## Income Eligibility Breakdown No manufacturer-specific income limits exist. For reference, general programs like Medicare Extra Help use Federal Poverty Level (FPL) guidelines: | Household Size | Annual Income Limit (100% FPL, 2026 est.) | Extra Help Eligibility (typically <135-150% FPL) | |----------------|-------------------------------------------|-------------------------------------------------| | Individual | ~$15,060 | <$20,000 | | Couple | ~$20,440 | <$27,000 | | Family of 3 | ~$25,820 | <$34,000 | | Family of 4 | ~$31,200 | <$41,000 | *Notes: FPL adjusts yearly; Extra Help offers no deductible, low copays. Xacduro not typically outpatient, so hospital billing applies.[2] Always verify current FPL at medicare.gov.* ## Insurance Requirements **No PAP insurance rules apply** since none exists.[1] Key considerations: - **Medicare**: Covered under Part A (hospital) for HABP/VABP; Part D for any outpatient use. Use Extra Help if income-qualified (limits premiums/deductibles/copays). New 2025 Payment Plan spreads costs.[2] - **Commercial/Private**: Check prior authorization; hospital stays often covered. - **Medicaid**: Usually covers hospital antibiotics fully for eligible patients. - **Uninsured**: Hospitals may offer financial aid; contact billing department.[2][3] Xacduro is distributed via specialty channels like ASD Healthcare (1-800-746-6273), Cardinal Health, or McKesson—ask providers for samples or bridging supply.[3] ## Step-by-Step Guide to Access Xacduro Affordably 1. **Confirm Prescription**: Discuss with your doctor if Xacduro is appropriate for your *Acinetobacter* infection.[1] 2. **Check Insurance**: Contact your plan for coverage details, prior auth, or appeals. For Medicare, review Part D options during Open Enrollment.[2] 3. **Apply for Extra Help (Medicare)**: Visit ssa.gov or call 1-800-MEDICARE. Provide income/assets proof; approval reduces costs significantly.[2] 4. **Explore Discounts**: Use GoodRx for any outpatient fills (though primarily hospital-use).[2] Inquire about hospital charity care or payment plans. 5. **Contact Distributors**: For urgent needs, healthcare providers can order via ASD (1-800-746-6273), Cardinal (1-866-677-4844), or McKesson (1-877-625-2566).[3] 6. **State Programs**: Search Medicare's tool for State Pharmaceutical Assistance Programs (e.g., Pennsylvania PACE).[2] 7. **Manufacturer Inquiry**: Call Menarini Group or visit xacduro.com to ask about unlisted support (none confirmed).[1] ## Timeline and Delivery **No PAP processing time** as none exists. Hospital delivery is immediate upon order.[1][3] - Insurance verification: 1-5 days. - Extra Help approval: 4-6 weeks (expedited possible).[2] - Distributors ship to hospitals within 24-48 hours.[3] Xacduro vials (NDC 68547-111-10) are reconstituted for IV use in clinical settings—no home delivery.[1][3] ## Alternatives if Denied Coverage - **Switch Antibiotics**: Colistin (comparator in trials) or others per doctor.[1] - **Appeal Insurance**: Provide lab confirmation of susceptible *Acinetobacter*.[1] - **Financial Aid**: Hospital indigent programs, NeedyMeds.org, or RxAssist.org for general help. - **Clinical Trials**: Search clinicaltrials.gov for Xacduro studies. - **Medicare Changes**: Enroll in better Part D plan; use $2,000 cap.[2] ## Disclaimer This guide is for informational purposes only and not medical/financial advice. No PAP exists for Xacduro per available data (as of 2026).[1] Consult your healthcare provider, pharmacist, or Medicare counselor. Eligibility/costs vary; verify with official sources. Menarini Group reserves rights to future programs. Word count: 942.

Program information last verified: March 30, 2026