VYONDYS 53

Indicated For

Duchenne muscular dystrophy (DMD)

About This Medication

# SareptAssist Patient Guide: How to Get Vyondys 53 at Low or No Cost ## About This Program SareptAssist is Sarepta Therapeutics' patient assistance program designed to help uninsured, underinsured, and eligible insured patients access Vyondys 53 (golodirsen) at reduced or no cost. If you have been prescribed Vyondys 53 to treat Duchenne muscular dystrophy (DMD), this guide will help you understand how to apply and what to expect. ## About Vyondys 53 Vyondys 53 is a prescription medication called an antisense oligonucleotide that is used to treat Duchenne muscular dystrophy in patients with a specific genetic mutation. DMD is a rare, progressive muscle-weakening condition. Vyondys 53 works by helping the body produce functional dystrophin protein, which is absent or defective in people with DMD. Because Vyondys 53 is a specialty medication, it is expensive and typically requires careful management with your healthcare team and specialty pharmacy. ## Who Can Apply? You may be eligible for SareptAssist if you: - Have a valid prescription for Vyondys 53 from your doctor - Are a U.S. resident - Meet income eligibility requirements (see table below) - Have insurance that does not cover Vyondys 53, are underinsured, or are uninsured - Are not eligible for Medicare, Medicaid, or other government programs (or have exhausted those options) Eligibility is determined on a case-by-case basis. Even if you think you don't qualify, it's worth applying—program staff can review your specific situation. ## Income Eligibility Guidelines The SareptAssist program uses a sliding scale based on household size and income. While exact income thresholds vary depending on individual circumstances and program updates, here is a general reference: | Household Size | Approximate Maximum Income* | |---|---| | 1 person | Up to ~$55,000 | | 2 people | Up to ~$75,000 | | 3 people | Up to ~$95,000 | | 4 people | Up to ~$115,000 | | 5 people | Up to ~$135,000 | | 6+ people | Call program for details | *These figures are approximate and subject to change. Income limits may vary based on program guidelines and your specific situation. Please contact SareptAssist directly for the most current thresholds. ## Insurance Requirements The program works with most insurance types, including: - Commercial insurance - Medicare (with limitations) - Medicaid (varies by state) - Military insurance (TRICARE) - Uninsured patients Your insurance status will be evaluated as part of your application. If your insurance denies coverage or you have high out-of-pocket costs, you may still qualify for assistance. ## What You'll Need to Apply Before you start, gather these documents: 1. **Valid prescription** for Vyondys 53 from your physician 2. **Proof of income** (such as recent tax returns, pay stubs, or benefit statements) 3. **Insurance information** (if applicable—insurance card or details) 4. **Personal information** (name, date of birth, contact information) 5. **Doctor's contact information** for verification if needed ## Step-by-Step Application Instructions ### Step 1: Get Your Doctor's Prescription Make sure your doctor has written a prescription for Vyondys 53. The prescription should include your diagnosis, dosage, and treatment plan. ### Step 2: Visit the SareptAssist Website Go to **https://www.vyondys53.com/getting-support** to access the application portal. This is the main hub for all SareptAssist information and resources. ### Step 3: Choose Your Application Method The SareptAssist program accepts applications through multiple methods: - **Online application** through the website portal (fastest option) - **Phone assistance** by calling the program support line - **Paper application** that can be mailed in - **Healthcare provider submission** (your doctor's office may submit on your behalf) ### Step 4: Complete the Application Provide accurate information about: - Your household income - Family size - Current insurance status - Prescription details - Contact information If applying online, you can often upload documents directly. For phone or paper applications, you'll receive instructions on where to send documents. ### Step 5: Submit Supporting Documents Attach or mail copies of your income verification and prescription. Keep copies for your records. ### Step 6: Wait for Approval The program typically processes applications within **4 to 8 weeks**. You'll be notified of your status by phone or email. ## What Happens If You're Approved Once approved, you'll receive: - **Confirmation of eligibility** with program details - **Instructions for obtaining your medication** through a specialty or hospital pharmacy - **Cost information** (reduced copay, coinsurance, or no cost, depending on your situation) - **Contact information** for ongoing support and questions Your medication will be **shipped directly to your treatment location** via a specialty or hospital pharmacy that is contracted with Sarepta. You will not pick it up at a regular retail pharmacy. ## Timeline and Delivery - **Application processing:** 4–8 weeks typical - **Medication delivery:** Once approved, delivery to your specialty pharmacy is usually arranged within 1–2 weeks - **Duration:** Your assistance continues as long as you remain eligible and your prescription is active ## Additional Ways to Save: Savings Card Even if you don't qualify for SareptAssist, you may be eligible for a **Vyondys 53 Savings Card**. This card can help reduce your out-of-pocket costs if you have insurance. **Learn more:** https://prescriberpoint.com/therapies/vyondys-53-35c227d/financial-assistance The savings card is separate from the patient assistance program and may have different eligibility requirements. ## What If You're Denied? If your application is denied: 1. **Ask for the reason.** The program must explain why you don't qualify. 2. **Ask about reapplication.** Your situation may change, and you may be able to reapply later. 3. **Explore alternatives:** - Check with your state Medicaid program - Look into disease-specific foundations that support DMD patients - Visit NeedyMeds.org for additional resources - Discuss cost-sharing options with your healthcare provider 4. **Contact patient advocacy.** Organizations supporting DMD patients can sometimes help with program navigation. ## Important Reminders - **Don't delay treatment** while waiting for approval. Talk to your doctor about temporary options. - **Keep documents updated.** Notify SareptAssist if your income or insurance changes. - **Be honest on the application.** False information can result in denial or program removal. - **Save everything.** Keep copies of your application, approval letter, and all communications. - **Reauthorization:** Check with the program about whether you need to reapply annually or if approval is ongoing. ## Contact and Support - **Website:** https://www.vyondys53.com/getting-support - **Application & Questions:** Use the online portal or call the SareptAssist support team - **For Prescription Issues:** Contact the specialty pharmacy handling your delivery ## Legal Disclaimer This guide is for informational purposes only and does not constitute medical advice or a guarantee of eligibility or coverage. Program eligibility, income thresholds, coverage policies, and application procedures are subject to change. For the most current and accurate information about SareptAssist, please visit the official website or contact the program directly. Always consult with your healthcare provider regarding your treatment plan and medication needs.

Program information last verified: March 25, 2026