Vegzelma

Indicated For

Metastatic Colorectal Cancer, Non-Small Cell Lung Cancer, Glioblastoma, Ovarian Cancer

About This Medication

# Celltrion CONNECT® Patient Assistance Program Patient Guide: How to Get Vegzelma (bevacizumab-adcd) at Low or No Cost Vegzelma (bevacizumab-adcd) is a biosimilar prescription medicine used to treat certain types of advanced cancers, and the **Celltrion CONNECT® Patient Assistance Program (PAP)** helps eligible patients who are uninsured, underinsured, or lack coverage get it at no cost. This guide explains everything you need to know in simple terms, from eligibility to applying and what to do if you're denied. ## About Vegzelma (bevacizumab-adcd) **Vegzelma** is an injectable medication that works by blocking a protein called vascular endothelial growth factor (VEGF), which helps tumors grow new blood vessels. It's approved for several serious cancers when used with chemotherapy or alone: - **Non-small cell lung cancer (NSCLC)**: Unresectable, locally advanced, recurrent, or metastatic non-squamous NSCLC, combined with carboplatin and paclitaxel as first-line treatment.[1][4] - **Ovarian, fallopian tube, or primary peritoneal cancer**: - Stage III or IV disease after initial surgery, with carboplatin and paclitaxel, followed by Vegzelma alone.[4] - Platinum-resistant recurrent disease (up to 2 prior regimens), with paclitaxel, pegylated liposomal doxorubicin, or topotecan.[4] - Platinum-sensitive recurrent disease, with carboplatin and paclitaxel or gemcitabine, followed by Vegzelma alone.[4] - **Cervical cancer**: Persistent, recurrent, or metastatic, combined with chemotherapy.[4] Vegzelma is a **biosimilar** to the original Avastin (bevacizumab), meaning it's highly similar in safety, effectiveness, and quality but often more affordable. It's given intravenously by a healthcare provider, typically every 2 or 3 weeks. Common side effects include high blood pressure, fatigue, bleeding, and serious risks like gastrointestinal perforation or infusion reactions—discuss these with your doctor.[1][4] ## Who Qualifies for the Program? The **Celltrion CONNECT® Patient Assistance Program** is for patients facing financial hardship who can't afford Vegzelma due to lack of insurance coverage. Key qualifications include:[2][5] - **Uninsured or functionally uninsured**: No insurance at all, or your plan doesn't cover Vegzelma (you're responsible for 100% of the cost).[5] - **Underinsured or lack coverage**: Insurance exists but doesn't help with this drug.[2] - **Household income limits**: Specific limits apply based on household size and Federal Poverty Level (FPL), but exact percentages aren't publicly listed. **Celltrion CONNECT® will evaluate your eligibility**—they consider your full financial situation.[2][5] - Prescribed Vegzelma by a U.S. licensed healthcare provider. - U.S. resident (proof required). **Note**: This is separate from the Celltrion CARES™ Co-pay Program, which helps commercially insured patients pay as little as $0 copay per month.[2] Celltrion CONNECT® offers both and can guide you. ## Income Eligibility Breakdown Household income thresholds aren't fixed publicly, but programs like this typically use 400-500% of the FPL or similar. Contact Celltrion CONNECT® at (877) 812-6662 for a personalized evaluation—they'll review your proof of income.[2] Here's a general example table based on common PAP structures (confirm with program for 2026 FPL): | Household Size | Example Max Annual Income (at 400% FPL) | Notes | |---------------|-----------------------------------------|-------| | 1 | ~$60,000 | Varies; Celltrion evaluates[2] | | 2 | ~$81,000 | Household income only[5] | | 3 | ~$102,000 | Includes all household members | | 4 | ~$123,000 | Add ~$21,000 per additional person | **Call (877) 812-6662 (Mon-Fri, 8 AM-8 PM ET)** to check your exact eligibility—no commitment needed.[1][2] ## Insurance Requirements - **Primary focus**: Uninsured, underinsured, or functionally uninsured (product not covered, 100% out-of-pocket).[2][5] - **Medicare/Medicaid**: Often ineligible for free drug PAPs, but check Celltrion CONNECT® for alternatives like co-pay help if commercially insured.[2] - Celltrion CONNECT® helps with **benefits investigation**, prior authorizations (PA), appeals, and claims.[2] ## Step-by-Step Application Process Applications are **multiple methods**—phone, online, or fax—for flexibility.[1][2] 1. **Contact Celltrion CONNECT®**: Call **(877) 812-6662** (Mon-Fri, 8 AM-8 PM ET) or visit **www.celltrionconnect.com/vegzelma**. Speak to a Case Coordinator for free help.[1][2] 2. **Gather Documents**: - **Proof of income** (tax returns, pay stubs, W-2s for all household).[5] - **Proof of residency** (utility bill, lease).[5] - **Proof of insurance status** (denial letter, insurance card showing no coverage).[2][5] - Prescription and doctor's info. 3. **Complete Enrollment**: Use the digital form at www.celltrionconnect.com, fax to 614-633-2259 or 833-912-3707, or provider submits.[2][5] 4. **Provider Signs**: Doctor certifies medical need and consents to sharing info.[5] 5. **Submit**: Celltrion reviews quickly. **Field Reimbursement Managers (FRMs)** assist providers with insurance navigation.[1] ## Timeline and Delivery - **Processing time**: Not specified—call for updates, but PAPs often approve in days to weeks.[1][2] - **Delivery**: Shipped free to your home or doctor's office.[5] - **Reauthorization required**: Yes, periodic recertification of eligibility.[5] ## Alternatives if Denied - **Biosimilar options** (all bevacizumab products, often similar programs): - **Avastin (bevacizumab)** (original reference).[provided] - **Mvasi (bevacizumab-awwb)**.[provided] - **Zirabev (bevacizumab-bvzr)**.[provided] - **Alymsys (bevacizumab-maly)**.[provided] - Ask Celltrion CONNECT® about **Celltrion CARES™ Co-pay Program** if commercially insured ($0 copay possible).[2] - Other resources: NeedyMeds, PAN Foundation, or state programs. - Appeal denial or reapply with more docs. ## Important Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. **Eligibility, terms, and income limits can change**—always verify directly with **Celltrion CONNECT® at (877) 812-6662** or www.celltrionconnect.com/vegzelma. Not medical advice; consult your doctor for treatment decisions. Celltrion may share your info for support services.[5] Program not for federally reimbursed patients in some cases. Word count: ~950.

Program information last verified: March 30, 2026