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Cardiology

TYVASO DPI

Generic: treprostinil

Manufacturer: United Therapeutics  ·  Program: United Therapeutics Cares Co-Pay Assistance Program

Apply for assistance

Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Patients with commercial (private) insurance only. Patients using Medicare, Medicaid, or any other state or federal government program are not eligible. Patients who transition to government coverage during program participation lose eligibility.

Residency

United States or Puerto Rico resident. Subject to additional state law restrictions; patients in select states may not be eligible.

Income Threshold

Up to 400% FPL

Individual Income Limit

$58,320/year

Program Information

Processing Time

2–3 weeks

Delivery Method

shipped to patient or physician office

Application Method

Multiple

Indicated for

Pulmonary Arterial Hypertension (PAH), Pulmonary Hypertension associated with Interstitial Lung Disease (PH-ILD)

About This Medication

United Therapeutics Cares Co-Pay Assistance Program Patient Guide: How to Get TYVASO DPI at Low or No Cost

TYVASO DPI (treprostinil) is an inhaled medication used to treat pulmonary arterial hypertension (PAH) and certain types of interstitial lung disease (ILD). The United Therapeutics Cares Co-Pay Assistance Program helps eligible patients with commercial insurance pay as little as $0 co-pay per prescription, covering the cost of the drug up to an annual maximum benefit.[1][2][3]

About TYVASO DPI

TYVASO DPI is a dry powder inhaler form of treprostinil, a prostacyclin analog that helps relax blood vessels in the lungs to improve blood flow and reduce symptoms of PAH or PH-ILD. Unlike the nebulized version (TYVASO), the DPI version is portable and doesn't require mixing solutions, making it easier for daily use—typically 4 times a day.[1][2] It's prescribed for FDA-approved uses and delivered only through specialty pharmacies like Accredo or CVS Specialty.[2]

This guide focuses on the Co-Pay Assistance Program, but note there's also a separate Patient Assistance Program (PAP) for uninsured or underinsured patients—call (844) 864-8437 to check eligibility.[4][8]

Who Qualifies?

This program is designed for patients with private commercial insurance facing high out-of-pocket costs. Key requirements include:

  • U.S. resident (including Puerto Rico, subject to state restrictions).[5]
  • Valid prescription for TYVASO DPI for an FDA-approved indication.[3][8]
  • Commercial (private) insurance only—no government programs.[1][3]
  • Not combining with other discounts, coupons, or savings offers.[3]

Important: No specific income thresholds are listed for the co-pay program, making it accessible regardless of income as long as you have qualifying insurance. However, the separate PAP has income guidelines for uninsured patients.[4][8]

Income Eligibility Breakdown

The Co-Pay Assistance Program does not impose income limits. Here's a simple overview:

Eligibility FactorDetails
Income ThresholdNone required—open to all with commercial insurance.
Separate PAPIncome-based for uninsured/underinsured; contact program for details.
Annual BenefitCovers co-pay up to a maximum (exact amount not specified; patient responsible for remainder). Program valid only for drug cost, not supplies.

If you're uninsured, explore the PAP instead.[8]

Insurance Requirements

  • Eligible: Commercial/private insurance plans.[1][3][4]
  • Not Eligible: Medicare, Medicaid, or any federal/state government program. If you switch to government coverage, you lose eligibility immediately.[3]
  • The program covers your co-pay for the medication only—not supplies, administration costs, or other expenses.[1][3]
  • Pharmacists/prescribers cannot seek reimbursement from insurance for the program's benefit.[3]

Your specialty pharmacy and Patient Navigator will verify coverage before approval.[2]

Step-by-Step Application Process

Enrollment is straightforward with multiple methods. Expect support from your doctor, United Therapeutics Cares, and specialty pharmacies.[2]

  1. Talk to Your Doctor: Ask them to send a referral/prescription to a specialty pharmacy (Accredo: 1-866-344-4874 or CVS Specialty: 1-877-242-2738) or United Therapeutics Cares.[2]

  2. Enroll in the Program:

  3. Verification: Your Patient Navigator or specialty pharmacy contacts your insurer to confirm coverage and benefits. They'll review your eligibility.[2]

  4. Get Your Program ID: Once approved, receive a unique ID (one per patient, non-transferable).[3]

  5. Prescription Fulfillment: Specialty pharmacy coordinates delivery to your home. They'll train you on use and provide 24/7 support.[2][4]

Tip: Answer calls from the pharmacy or support team—they'll guide you![2]

Timeline and Delivery

  • Processing: Varies; specialty pharmacy verifies insurance quickly, often within days. Approval depends on your insurer's response.[2]
  • Delivery: Ships directly to your home via Accredo or CVS Specialty. Coordinate a convenient time; refills are managed ongoing.[2][4]
  • Ongoing Support: Regular check-ins from Patient Navigators for education, refills, and questions.[1][2][7]

Exact processing time isn't specified—call for your status.[1]

Alternatives if Denied or Ineligible

  • Government Insurance: Not eligible here, but check state Medicaid or Medicare Extra Help.
  • Uninsured/Underinsured: Apply to the United Therapeutics ASSIST Patient Assistance Program (PAP) for potentially free medication if you meet income guidelines and are a U.S. resident.[4][8]
  • Other Resources: Pulmonary Hypertension Association lists additional aid; explore generic options or manufacturer PAPs.[9]
  • Appeal: Contact United Therapeutics Cares to discuss denial reasons and next steps.[1]
  • Charity Foundations: Patient Access Network (PAN) or HealthWell Foundation may help with copays for PAH.

Refills and Reauthorization

Your specialty pharmacy handles refills seamlessly. Patient Navigators monitor and coordinate—no formal reauthorization details provided, but expect periodic coverage checks.[2][4]

Disclaimer

This guide is for informational purposes based on publicly available program details as of March 2026. Eligibility, benefits, and terms can change—always verify with United Therapeutics Cares at (844) 864-8437 or the official website. Not a substitute for medical or financial advice. Program not valid where prohibited by law; see full Terms & Conditions online.[1][3][5] United Therapeutics reserves the right to modify or end the program. Consult your doctor before starting TYVASO DPI.

Program information last verified: March 30, 2026

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