TWYNEO

Indicated For

acne

About This Medication

# Mayne Pharma Patient Savings Program: How to Get TWYNEO at Low or No Cost ## About TWYNEO TWYNEO is a prescription acne treatment cream that combines two powerful acne-fighting ingredients: tretinoin and benzoyl peroxide. Using microencapsulation technology, TWYNEO delivers both active ingredients in a single once-daily application, making it a convenient treatment option for moderate acne. ## Program Overview Mayne Pharma offers the **CAREConnect Patient Savings Card** program to help eligible patients access TWYNEO at reduced or no cost. This program is designed to make this prescription medication more affordable for patients with commercial insurance or those paying out-of-pocket. ## Who Qualifies To be eligible for the TWYNEO Patient Savings Card, you must meet ALL of the following criteria: - Be a clinically appropriate patient with a valid prescription from your doctor - Be at least 18 years old and less than 65 years old (for adult-indicated products) - Be a U.S. resident (including the District of Columbia) - Have a commercial insurance plan that covers TWYNEO, OR be an uninsured patient - Have met your insurance deductible (if applicable) - NOT be enrolled in Medicare, Medicaid, TRICARE, Medicare Advantage, Part D, Medigap, VHA, DOD, IHS, or state pharmaceutical assistance programs - NOT have private insurance that fully covers your prescription costs - NOT be a Medicare-eligible individual enrolled in an employer-sponsored health plan or retiree prescription drug benefit program ## Cost Breakdown | Patient Type | Your Cost | |---|---| | Commercially insured, eligible patients | $0 copay | | Uninsured patients | $45 per prescription | | Out-of-pocket costs | May vary by individual | **Important Note:** The typical cash price for TWYNEO is approximately $1,318–$1,354 per 30-gram pump bottle without assistance. The savings card can reduce this significantly. ## Insurance Requirements Your insurance situation determines your eligibility: **You ARE eligible if you have:** - Commercial health insurance (including healthcare exchange plans) - A prescription drug plan through your employer - No insurance (uninsured patients) **You ARE NOT eligible if you have:** - Medicare or Medicare Advantage coverage - Medicaid or state-funded healthcare programs - TRICARE or military healthcare - Federal employee health benefits (FEHB) - Veterans Affairs (VA) coverage - Indian Health Service (IHS) coverage - Private insurance that fully covers your prescription - An employer-sponsored plan as a Medicare-eligible retiree ## How to Apply ### Step 1: Get a Prescription Visit your dermatologist or healthcare provider and request a prescription for TWYNEO. Make sure your doctor confirms you are a clinically appropriate candidate for this medication. ### Step 2: Download or Request the Savings Card You can download the Mayne Pharma Patient Savings Card from the TWYNEO website (twyneo.com/savings-support) or request one from your healthcare provider's office. The card is free. ### Step 3: Verify Your Eligibility Before filling your prescription, confirm that: - Your insurance plan covers TWYNEO (or you are uninsured) - You meet all eligibility requirements listed above - You have met your insurance deductible ### Step 4: Fill Your Prescription Take your prescription and the Mayne Pharma Patient Savings Card to a participating pharmacy. Show the card to the pharmacist when filling your prescription. The pharmacist will process the card at the time of dispensing. ### Step 5: Pay Your Copay Pay your copay amount ($0 for insured patients or $45 for uninsured patients) at the pharmacy. ## Program Limitations - **Supply Limit:** The card covers up to a 30-day supply per prescription, with a maximum of 12 months of supply per patient - **One Card Per Patient:** You can only use one savings card per patient - **Prior Authorization:** Your insurance may require prior authorization before approval - **Deductible Requirements:** You must meet your insurance deductible before the card can be used - **Program Expiration:** All prescriptions must be filled before the program expires - **Not Health Insurance:** This card is NOT health insurance and does not replace your medical coverage ## Timeline and Delivery Once you present your savings card at the pharmacy: - **Processing:** The pharmacist will process your prescription immediately - **Approval:** Most claims are processed quickly through Change Healthcare - **Dispensing:** You will receive your TWYNEO prescription the same day or within your pharmacy's standard timeframe - **Reimbursement:** Reimbursement is handled between the pharmacy and the program administrator (Apollo Care) If you have questions about online processing or claim status, contact the Help Desk at **1-800-433-4893**. ## What If You're Denied? If your application is denied, possible reasons include: - You are enrolled in a government-funded healthcare program (Medicare, Medicaid, etc.) - You do not have commercial insurance - Your insurance fully covers the prescription cost - You have not met your insurance deductible - You are outside the eligible age range - You do not meet clinical appropriateness criteria **Next Steps:** - Contact the Help Desk at 1-800-433-4893 to understand why you were denied - Ask your healthcare provider about alternative acne treatments - Explore other discount programs like SingleCare (which offers up to 80% discounts on TWYNEO) - Check if you qualify for Mayne Pharma's CAREConnect program for uninsured patients ## Refills and Reauthorization The savings card is valid for up to 12 months of supply. You can use the same card for multiple refills during this period, as long as: - Your prescription remains valid - You continue to meet eligibility requirements - The program has not expired - You have not exceeded the 12-month supply limit For each refill, present your card to the pharmacist just as you did for your initial prescription. ## Important Disclaimers - This program is not health insurance and does not replace your medical coverage - You cannot use this card if you submit claims to federal or state-funded programs - Eligibility requirements and program terms may change without notice - This offer is void where prohibited by law - In California and Massachusetts, this offer becomes void if a lower-cost generic equivalent or OTC alternative becomes available - Doctor's office visits, lab work, and other ancillary services are not covered by this card - Maximum reimbursement limits may apply - Patient out-of-pocket expenses may vary ## Contact Information **Mayne Pharma Help Desk:** 1-800-433-4893 **Program Administrator:** Apollo Care **Website:** twyneo.com/savings-support ## Additional Resources If you do not qualify for the Mayne Pharma savings card, explore these alternatives: - **SingleCare:** Offers up to 80% discounts on TWYNEO at participating pharmacies - **GoodRx:** Provides prescription discounts and coupons - **Your Insurance Company:** Ask about formulary coverage and prior authorization requirements - **Patient Assistance Programs:** Contact Mayne Pharma directly at maynepharmaaccess.com for additional support options

Program information last verified: March 30, 2026