TUKYSA

Indicated For

HER2+ metastatic breast cancer, RAS wild-type HER2+ metastatic colorectal cancer

About This Medication

# Pfizer Oncology Together Patient Guide: How to Get TUKYSA (tucatinib) at Low or No Cost TUKYSA (tucatinib) is a prescription medication used to treat certain types of advanced cancers, and Pfizer offers support through **Pfizer Oncology Together** and related programs like Seagen Secure to help eligible patients access it affordably.[1][2][4] ## About TUKYSA and Who It Helps **TUKYSA (tucatinib)** is an oral targeted therapy for adults with **HER2-positive metastatic breast cancer** that has spread (including to the brain) or cannot be removed by surgery, after prior anti-HER2 treatments. It's taken with trastuzumab and capecitabine.[1] It is also approved for **RAS wild-type HER2-positive colorectal cancer** that is metastatic or unresectable, after chemotherapy with fluoropyrimidine, oxaliplatin, and irinotecan.[1] This approval is based on tumor response rates, with ongoing studies to confirm benefits.[1] TUKYSA targets the HER2 protein on cancer cells to slow growth. It's typically prescribed by oncologists for patients whose cancer has progressed despite other therapies. Always consult your doctor to see if it's right for you. ## Who Qualifies for Assistance? Pfizer provides multiple pathways based on insurance status: - **Commercially insured patients**: Eligible for **Co-Pay Assistance**, paying as little as **$0 per month** for TUKYSA (up to $10,000 savings/year) and capecitabine ($6,000/year if combined).[4][5][9] Not for government insurance like Medicare/Medicaid. - **Uninsured or publicly insured (Medicare, Medicaid, etc.)**: **Pfizer Patient Assistance Program (PPAP)** offers free medicine if income ≤ **500-600% FPL** for oncology drugs like TUKYSA, no prescription coverage or unable to afford copays.[2] - **Institutional program**: Free via health centers for uninsured at ≤ **300% FPL**.[2] - **New patients**: 30-day free voucher.[4] **Seagen Secure** (part of Pfizer support) offers copay help for commercial insurance and assistance for qualifiers.[1] ## Income Eligibility Breakdown Income limits vary by program and family size. PPAP uses Federal Poverty Level (FPL); check current FPL at healthcare.gov. | Household Size | 300% FPL (Institutional) | 500% FPL (Oncology Estimate) | 600% FPL (Oncology Max) | |----------------|---------------------------|------------------------------|--------------------------| | 1 | $45,180 | $75,300 | $90,360 | | 2 | $61,320 | $102,200 | $122,640 | | 3 | $77,460 | $129,100 | $154,920 | | 4 | $93,600 | $156,000 | $187,200 | *Notes: Adjusted annually; migrant/homeless presumed eligible for institutional. Exact % for TUKYSA likely 500-600% per oncology guidelines. Verify with Pfizer.[2] ## Insurance Requirements - **Commercial insurance**: Primary option for copay cards; specialty pharmacy verifies coverage first.[1][4] - **Public insurance (Medicare/Medicaid/VA/TRICARE)**: Ineligible for copay; use PPAP if income-qualified and can't afford copays.[2][4] - **Uninsured**: PPAP or institutional programs.[2] Specialty pharmacies contact your insurer to confirm benefits before filling.[1] ## Step-by-Step Application Process 1. **Talk to your doctor**: Get a valid prescription for FDA-approved use.[2] 2. **Contact support**: Call **Pfizer Oncology Together** (1-844-4PFIZER) or visit pfizeroncologytogether.com. Enroll in Seagen Secure via tukysa.com.[1][3] 3. **Specialty pharmacy**: Doctor sends Rx to one (e.g., via office/hospital or network). They verify insurance.[1] 4. **Apply for assistance**: - Commercial: Sign up for copay card online/phone; get $0 copay if eligible.[4][5] - Uninsured/public: Submit PPAP app with income proof, Rx, via doctor or pfizerrxpathways.com.[2] 5. **Submit documents**: See FAQ for details. 6. **Approval**: Expect call from pharmacy/support.[1] ## Timeline and Delivery - **Processing**: Specialty pharmacy verifies insurance quickly (days); assistance approval varies (1-2 weeks for PPAP).[1][2] - **Delivery**: Home delivery, office pickup, or hospital pharmacy.[1] First fill may include free 30-day voucher.[4] - **Refills**: Automatic via specialty pharmacy; reauthorization may apply yearly.[2] ## Alternatives if Denied or Ineligible - **Appeal**: Resubmit with more docs or doctor letter.[2] - **Other aid**: State programs, health centers, or generic alternatives (none listed for TUKYSA).[2] - **Biosimilars**: No alternatives noted.[ ] - **Independent foundations**: Search via Needymeds.org or CancerCare.org. - **Free trial voucher** if new.[4] ## Important Disclaimer This guide is for informational purposes only and not medical/financial advice. Eligibility, terms change; Pfizer doesn't guarantee assistance.[1][4] Consult your healthcare provider and Pfizer directly (1-844-4PFIZER). Programs may end without notice. Income based on current FPL; verify at application. Not for government-insured copay aid.

Program information last verified: March 29, 2026