Trazimera

Indicated For

HER2-positive breast cancer, gastric cancer

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get Trazimera (trastuzumab-qyyp) at Low or No Cost Trazimera (trastuzumab-qyyp) is a biosimilar medication used to treat certain types of breast cancer and gastric cancer by targeting the HER2 protein on cancer cells, helping to slow or stop their growth. The **Pfizer Patient Assistance Program** offers eligible patients free access to Trazimera if they meet specific financial and insurance criteria, making life-saving treatment more accessible for those who cannot afford it.[1][5] ## Who Qualifies for the Program? This program is designed for **US residents** who are **uninsured or underinsured** and struggle to pay for their medications. Key eligibility factors include: - **Residency**: Must live in the US or a US territory. - **Age**: Typically 18 years or older. - **Prescription**: Valid prescription from a US-licensed healthcare provider for outpatient use. - **Insurance Status**: Not enrolled in government insurance like Medicare (with exceptions for certain Medicare Part D patients who haven't met their out-of-pocket maximum and are in the Medicare Prescription Payment Plan), and **no commercial insurance**.[5][7][9] - **Income**: Household income at or below **400% of the Federal Poverty Level (FPL)**.[1] - **Diagnosis**: FDA-approved diagnosis required.[3][10] Patients must certify they cannot afford their medication and provide supporting documents. Commercially insured patients are explicitly ineligible.[3][5][10] ## About Trazimera (trastuzumab-qyyp) **Trazimera** is a biosimilar to Herceptin (trastuzumab), meaning it is highly similar in quality, safety, and efficacy but often more affordable. It is administered via intravenous infusion and is prescribed for: - HER2-positive (HER2+) metastatic breast cancer. - HER2+ early-stage breast cancer as adjuvant therapy. - HER2+ metastatic gastric or gastroesophageal junction adenocarcinoma. Common side effects include infusion reactions, heart problems, lung issues, and fatigue. Always discuss risks with your doctor. As a biosimilar, Trazimera offers the same therapeutic benefits as the reference product at potentially lower costs through programs like this.[1] ## Income Eligibility Breakdown Eligibility is based on **pre-tax household income** not exceeding **400% of the Federal Poverty Level (FPL)**. The FPL adjusts annually; check current guidelines at the program site. Here's a table for 2026 estimates (verify exact figures via PfizerRxPathways.com as they update yearly): | Household Size | 100% FPL | 400% FPL Threshold | |---------------|----------|---------------------| | 1 | $15,060 | $60,240 | | 2 | $20,440 | $81,760 | | 3 | $25,820 | $103,280 | | 4 | $31,200 | $124,800 | | +1 per person | +$5,380 | +$21,520 | **Notes**: Include all household income sources (wages, Social Security, pensions). Proof required, such as tax returns (1040), W-2s, pay stubs, or SSA-1099. Electronic verification is optional; opt-out requires manual documents.[3][4][9] ## Insurance Requirements - **Uninsured**: Fully eligible if other criteria met. - **Underinsured**: Coverage denied for Trazimera (after appeal), or government-insured but unable to afford costs (e.g., Medicare Part D patients not at $0 co-pay, enrolled in Payment Plan, with proof). **No commercial insurance** allowed.[5][7][9] - Submit front/back of insurance cards if applicable. - Exhaust other assistance first if required.[5] ## Step-by-Step Application Process 1. **Check Eligibility**: Visit www.PfizerRxPathways.com, use the Program Finder, enter "Trazimera". Confirm you qualify.[1][5] 2. **Gather Documents**: - Proof of income (tax return pages 1-2, W-2, 2 pay stubs, SSA-1099). - Proof of residency (utility bill, etc.). - Prescription for Trazimera. - Insurance info (cards, denial letter if underinsured).[4][9] 3. **Start Application**: - **Online (Preferred)**: Use Pfizer PAP Connect at pfizerrxpathways.com. New patients create account; upload docs, track status.[2][8] - **Phone**: Call (800) 736-0003 for help or manual forms.[1] - **Mail/Fax**: Download form, complete patient/doctor sections, send to P.O. Box 66585, St. Louis, MO 63166-6585 or fax 866-470-1748.[4] 4. **Doctor's Role**: Prescriber completes certification, confirms diagnosis. 5. **Sign & Submit**: Patient signs consents, including income affidavit and Medicare certification if applicable.[3][10] 6. **Wait for Notification**: 2-4 weeks.[1][4] ## Timeline and Delivery - **Processing**: 2-3 weeks typically; up to 4 weeks.[1][4] - **Notification**: Letter or online status update with enrollment term (often 1 year).[4] - **Delivery**: Free medication shipped to your home or doctor's office. Refills via PAP Connect or phone.[2][8] - **Reauthorization**: Required annually or as specified; resubmit updated docs.[1] ## Alternatives if Denied - **Appeal**: Contact program for reasons (e.g., income too high).[1] - **Biosimilars/Original**: Herceptin (trastuzumab) may be available via similar programs.[1] - **Other Resources**: State programs, NeedyMeds.org, RxAssist.org, or manufacturer copay cards (if insured). Medicare Extra Help. Nonprofit foundations like Patient Access Network.[5] - **Pfizer Oncology Together**: For insured patients, check p Pfizerpro.com.[6] ## Disclaimer This guide is for informational purposes only and based on available program details as of 2026. Eligibility rules change; always verify at PfizerRxPathways.com or call (800) 736-0003. Not medical advice—consult your doctor. Pfizer reserves rights to modify/deny. Word count: 1028.

Program information last verified: March 30, 2026