TRAZIMERA

Indicated For

HER2-positive breast cancer, metastatic breast cancer

About This Medication

# Pfizer Oncology Together Patient Guide: How to Get TRAZIMERA (trastuzumab-qyyp) at Low or No Cost TRAZIMERA (trastuzumab-qyyp) is a biosimilar medication used to treat certain types of HER2-positive breast cancer and gastric cancer, and the **Pfizer Oncology Together** program helps eligible patients access it at low or no cost through co-pay assistance or patient assistance options. ## About TRAZIMERA TRAZIMERA is an injectable biosimilar to Herceptin (trastuzumab), targeting HER2-overexpressing cancers. It is FDA-approved for: - **Adjuvant breast cancer**: In node-positive or high-risk node-negative HER2-overexpressing breast cancer, used with regimens like doxorubicin, cyclophosphamide, paclitaxel/docetaxel; docetaxel/carboplatin; or as a single agent after anthracycline therapy. High-risk features include tumor >2 cm, age <35, or grade 2/3 for ER/PR-positive cases[1][3]. - **Metastatic breast cancer**: With paclitaxel for first-line HER2-overexpressing metastatic disease, or as monotherapy after chemotherapy[1][3]. - **Metastatic gastric cancer**: With cisplatin/capecitabine or 5-FU for HER2-overexpressing metastatic gastric/gastroesophageal junction adenocarcinoma[1][3]. Patients must be selected using an FDA-approved companion diagnostic for trastuzumab products. Always consult your doctor for full prescribing information, including **boxed warnings** for heart failure and infusion reactions[1][3]. ## Who Qualifies for Pfizer Oncology Together? **Pfizer Oncology Together** offers **co-pay assistance** for commercially insured patients (up to $25,000 per calendar year, no income limits) and a **Patient Assistance Program (PAP)** for uninsured or government-insured patients denied coverage (income ≤500% FPL)[3][4]. - **Co-pay program**: Commercially insured patients; pay as little as $0[3][4]. - **PAP**: No insurance, or denied by government insurance (e.g., Medicare after appeal); valid prescription; U.S. resident; treated by U.S. licensed HCP[2]. Commercially insured not eligible for PAP, even if uncovered[2]. ## Income Eligibility Breakdown Income limits apply to PAP (≤**500% Federal Poverty Level (FPL)**, adjusted for family size). No income requirements for co-pay assistance[3]. | Household Size | Annual Income Limit (500% FPL, approx. 2026)* | |----------------|------------------------------------------------| | 1 (Individual) | $73,600 | | 2 (Couple) | $99,200 | | 3 | $124,800 | | 4 | $150,400 | *Estimates based on 2026 FPL guidelines; confirm current levels. Adjusted annually[program data]. ## Insurance Requirements - **Commercial insurance**: Eligible for co-pay help (covers up to $25,000/year)[3][4]. - **Government insurance (Medicare/Medicaid)**: PAP possible if denied after appeal[2]. - **Uninsured**: PAP eligible if income-qualified[2]. Provide insurance details; program verifies benefits[2]. ## Step-by-Step Application Process 1. **Confirm eligibility**: Discuss with your doctor; get valid TRAZIMERA prescription[2]. 2. **Enroll**: Call **1-866-473-0088** or visit pfizeroncologytogether.com (patients/HCPs enroll separately)[program data][5]. Download form if needed[2][6]. 3. **Complete form**: Patient/caregiver fills pages 1-5 (income, Medicare if applicable, sign authorizations). HCP completes pages 6-8 (prescription, certification)[2]. 4. **Gather documents**: - Valid TRAZIMERA prescription. - Proof of income (e.g., tax return, pay stubs). - Insurance info[program data]. 5. **Submit**: Online at pfizeroncologytogether.com/pfizeroncologypatientenroll.com (patients) or pfizeroncologytogether-portal.com (HCPs); fax 1-877-736-6506 (code 8777366506); mail PO Box 220366, Charlotte, NC 28222[2][10]. 6. **Benefit verification**: Program checks insurance/co-pay[2]. Multiple methods available; phone support Mon-Fri[2]. ## Timeline and Delivery Processing time varies; expect benefit verification quickly via phone/email. Co-pay cards issued promptly for pharmacy/physician use. Medication shipped to patient or doctor's office[program data]. Refills/reauthorization required[program data]. Contact program for status. ## Alternatives if Denied - **Appeal denial** with HCP help. - **Biosimilars/originator**: Herceptin (trastuzumab), Herceptin HYLECTA[program data]. - **Other assistance**: Pfizer Oncology Together connects to resources[7]. Explore state programs, nonprofits via 1-866-473-0088. ## Disclaimer This guide is for informational purposes; eligibility/terms may change. Not medical/financial advice. Consult healthcare provider/insurer. Program details from Pfizer Oncology Together (2026); verify at pfizeroncologytogether.com or call 1-866-473-0088. Pfizer not liable for errors/omissions.

Program information last verified: March 25, 2026