Tibsovo

Indicated For

Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS), Cholangiocarcinoma

About This Medication

# ServierONE Patient Assistance Program (PAP) Patient Guide: How to Get **Tibsovo (ivosidenib)** at Low or No Cost Tibsovo (ivosidenib) is a targeted oral therapy approved for adults with **relapsed or refractory acute myeloid leukemia (AML)** with a specific genetic mutation called IDH1, as well as for certain **newly diagnosed AML patients** who cannot receive intensive chemotherapy due to comorbidities. The **ServierONE Patient Assistance Program (PAP)** from Servier Pharmaceuticals helps **uninsured or underinsured US residents** access Tibsovo at no cost if they meet income and other eligibility criteria. This guide explains everything you need to know in simple terms to apply successfully.[1][6] ## About Tibsovo (Ivosidenib) **Tibsovo** is a prescription tablet taken once daily to block the faulty IDH1 protein that causes cancer cells to grow in certain AML patients. It's a **targeted therapy**, meaning it attacks the specific mutation driving your leukemia rather than broadly killing fast-growing cells like traditional chemotherapy. Common side effects include fatigue, nausea, joint pain, and a condition called differentiation syndrome (swelling and fluid buildup)—your doctor will monitor you closely. Tibsovo is typically used continuously for as long as it works and you tolerate it well. Always take it with food at the same time each day, and do not stop without medical advice. This program provides the medication **free** to eligible patients, easing the financial burden of treatment that can cost tens of thousands per month without assistance.[1][6] ## Who Qualifies for the Program? The ServierONE PAP is designed for patients who **cannot afford their medication** due to lack of insurance coverage or high out-of-pocket costs. Key qualifications include: - **US residency**: You must live in the United States. - **Uninsured or underinsured**: No insurance, Medicare, Medicaid, commercial/private plans with denials, or high copays. - **Income limits**: Based on **household size** and **annual gross pre-tax income** (matching your 1040 tax form or W-2). Exact thresholds are not publicly listed and **vary**—contact ServierONE for your situation. - **Valid prescription**: For FDA-approved uses of Tibsovo, with diagnosis code (e.g., AML with IDH1 mutation). - **Physician involvement**: Your doctor must complete and sign parts of the application. **Notes**: Even Medicare patients may qualify if underinsured. The program assesses eligibility case-by-case, and approval is not guaranteed.[1][2][3] ## Income Eligibility Breakdown Income requirements are **income-based** relative to the Federal Poverty Level (FPL), but specific percentages are determined by Servier. Provide your **annual gross pre-tax household income** and **number of people in your household** (those who contribute to or depend on the income). Here's a general example table based on typical PAP structures (contact ServierONE at (800) 813-5905 for **your exact limits**): | Household Size | Estimated Max Annual Income (e.g., ~400-500% FPL)* | |----------------|---------------------------------------------------| | 1 (Individual) | $60,000 - $75,000 | | 2 (Couple) | $80,000 - $100,000 | | 3 | $100,000 - $125,000 | | 4 | $120,000 - $150,000 | | 5+ | Add ~$20,000 - $25,000 per person | *These are illustrative; **actual thresholds require program confirmation**. Income proof like 1040 forms, 1099s, or Social Security summaries is mandatory. Servier verifies everything to ensure fairness.[1][3] ## Insurance Requirements This program targets **uninsured or underinsured patients**. Submit copies of **both sides** of all insurance cards (medical and pharmacy). Check options like: - No insurance - Medicare - Medicaid - Commercial/private - Other If insured, include **prior authorization (PA) or appeal denial letters**. Medicare patients may qualify if the plan doesn't cover Tibsovo fully. Do **not** seek reimbursement from government programs for free medication received.[1][2][3] ## Step-by-Step Application Process Applying is straightforward with your doctor's help. Multiple methods available: 1. **Contact ServierONE**: Call **(800) 813-5905** (Mon-Fri, 8 AM-8 PM ET) or email USPatientServices@servier.com. A Patient Experience Manager guides you.[2][3] 2. **Get the Enrollment Form**: Download from servierone.com or request via phone. Options include **paper form** (fax to 1-844-409-1143 or 877-770-7102) or **eEnrollment** at servierone-enroll.com.[1][3][5] 3. **Fill Out Sections**: - **Patient info**: Name, DOB, SSN (optional for verification), address, phone. - **Insurance**: Check types, attach card copies. - **Diagnosis**: ICD-10 code, AML details (e.g., newly diagnosed? Comorbidities?). - **Financial**: Household size, income; opt for Care Manager support. - **Physician signs** Sections 4-5 (prescription, contact). - **Patient signs** Sections 6-7 (authorization, consent).[1][3] 4. **Gather Documents**: - Proof of income (1040, 1099, W-2, Social Security summary). - Proof of residency (utility bill, etc.). - Prescription. - Insurance docs/PA denials.[1] 5. **Submit**: Fax, mail, or eSubmit. Physician eSigns if electronic. ## Timeline and Delivery Processing time varies (typically 1-2 weeks), but a Patient Experience Manager follows up **within 1 business day** for missing info or welcome call. Once approved, Tibsovo is **shipped free** to your home or doctor's office. **Reauthorization is required** periodically—notify if income/insurance changes. Refills continue seamlessly if eligible.[1][3] ## Alternatives if Denied or No Other Options - **ServierONE Co-Pay Program**: For insured patients with copays (servierone-copay.com).[7] - **Quick Start Program**: Bridge therapy while insurance processes.[1] - **Other PAPs**: Check rxassist.org or NeedyMeds.org. - **State programs**, PAN Foundation, or CancerCare for grants. - **Appeal denial**: Resubmit with more docs or call for review. No biosimilar alternatives for Tibsovo exist.[1] ## Important Disclaimer This guide is for informational purposes only and based on publicly available program details as of 2026. **Servier may change eligibility, terms, or availability anytime**. It does not guarantee approval—contact ServierONE directly for personalized advice. Consult your healthcare provider before starting/stopping Tibsovo. Not medical or legal advice. Free medication cannot be resold or reimbursed.

Program information last verified: March 25, 2026