Tezspire

Indicated For

severe asthma

About This Medication

# Amgen Safety Net Foundation Patient Assistance Program Patient Guide: How to Get Tezspire (tezepelumab) at Low or No Cost Tezspire (tezepelumab) is an injectable monoclonal antibody medication used to treat severe asthma in adults and children aged 12 years and older whose asthma is not well-controlled with other treatments. The **Amgen Safety Net Foundation Patient Assistance Program** provides **Tezspire at no cost** to eligible patients who meet specific financial and insurance criteria, helping those facing high medication costs access this important therapy.[1][2] ## About Tezspire (tezepelumab) **Tezspire** is a biologic therapy administered by subcutaneous injection, typically every 4 weeks, to reduce asthma exacerbations, improve lung function, and lessen reliance on oral corticosteroids. It works by targeting thymic stromal lymphopoietin (TSLP), a key signaling protein in the inflammatory pathway of asthma, making it unique as it does not require evidence of specific eosinophil counts or other biomarkers for use. This broadens its potential benefit for patients with severe asthma unresponsive to standard therapies like inhaled corticosteroids or other biologics.[1] Severe asthma affects daily life, causing frequent attacks, hospitalizations, and reduced quality of life. Without assistance, Tezspire's list price can exceed $30,000 per year, creating a significant barrier. The Amgen Safety Net Foundation bridges this gap for qualifying individuals, ensuring treatment continuity.[2] ## Who Qualifies? Eligibility focuses on financial need, residency, and insurance status. Key requirements include: - **U.S. residency** (including Puerto Rico). - **Financial hardship**: Demonstrate inability to afford Tezspire, based on income and household size (needs-based; specific FPL percentages not publicly detailed). - **Age 18+** or with legal guardian authorization. - **Prescribed Tezspire** by a licensed U.S. healthcare provider (HCP). | Household Size | Income Threshold (Approximate, Needs-Based) | |----------------|--------------------------------------------| | 1 (Individual) | Not specified; evaluated case-by-case | | 2 (Couple) | Not specified; evaluated case-by-case | | 3 | Not specified; evaluated case-by-case | | 4 | Not specified; evaluated case-by-case | | 5+ | Not specified; evaluated case-by-case | **Notes**: The program uses a needs-based approach without fixed Federal Poverty Level (FPL) percentages listed. Applicants authorize a consumer credit check via the Fair Credit Reporting Act (FCRA) to verify financial eligibility. Changes in income must be reported within 30 days.[1][2] ## Insurance Requirements The program targets those without adequate coverage: - **Uninsured patients**: Fully eligible if other criteria met. - **Medicare Part B patients**: Eligible if no supplemental insurance covers Tezspire. - **Underinsured (including Medicare Part D)**: Eligible only if insurance excludes Tezspire (or generic/biosimilar), patient proves inability to afford out-of-pocket costs, not eligible for Medicaid/Extra Help, satisfies payer prior authorizations, and has no other funding options. **Ineligible if**: - Enrolled in Medicaid or Medicare Low-Income Subsidy (Extra Help). - Have insurance/employer in alternate funding programs (e.g., patient advocacy or specialty networks) requiring PAP application. - Auto-enrolled in Medicare Part D (must notify program immediately).[1][2] Patients certify no reimbursement requests from insurance/government for Foundation-provided medication. ## Step-by-Step Application Process 1. **Discuss with your doctor**: Confirm Tezspire prescription and obtain their signature on the enrollment form. Your HCP must provide proof of medical necessity. 2. **Contact Amgen Assist**: Call **(888) 897-7473** (1-888-TZSPIRE), 8am–8pm ET, Monday–Friday, for screening and form guidance. New applicants start here.[1] 3. **Complete the form**: Download from TEZSPIRETogetherHCP.com or request via phone. Sections include: - Patient and HCP info. - Financial details. - **Patient Certification** (accuracy, no reimbursement, report changes). - **Patient Authorization** (health data sharing, expires 5 years or 1 year post-last dose). - **FCRA Authorization** (credit check). - **U.S. State Law Consent** (health data processing; must consent to participate). Sign and date all required sections.[1] 4. **Gather documents**: - Completed, signed enrollment form (patient and HCP). - Proof of insurance (if applicable). - Medicare ID (if applicable).[2] 5. **Submit by fax**: Fax **all pages** to **1-888-388-6016**. No mail or online upload specified.[1] 6. **Follow up**: Track via phone. Notify of any insurance/financial changes within 30 days. ## Timeline and Delivery Processing time not specified; expect several weeks based on similar programs. Once approved, **Tezspire ships free** to your home or HCP's office. Track shipments via Amgen Assist. For refills/reauthorization (required), HCP receives notification; resubmit proof of ongoing eligibility.[1][2] ## Alternatives if Denied or Ineligible - **Appeal**: Contact Amgen Assist to review denial reasons (e.g., income, insurance mismatch). - **Other PAPs**: Check NeedyMeds.org or RxAssist.org for asthma biologics. - **Manufacturer support**: TEZSPIRETogetherHCP.com for copay cards (insured patients). - **Government aid**: Apply for Medicaid/Extra Help if eligible (disqualifies from this program). - **Patient advocacy**: Partnership for Prescription Assistance (PPARx.org). - **No biosimilars** available for Tezspire currently.[2] ## Important Disclaimer This guide summarizes publicly available info as of 2026; program details change. Consult Amgen Safety Net Foundation directly at (888) 897-7473 or your HCP for personalized advice. Approval not guaranteed; false info may disqualify. Not medical/financial advice—seek professional guidance. Program separate from Amgen commercial support.[1][2]

Program information last verified: March 25, 2026