Tezspire

Indicated For

uncontrolled severe asthma

About This Medication

# Tezspire Patient Assistance Program Patient Guide: How to Get Tezspire at Low or No Cost Tezspire (tezepelumab) is an injectable medication used to treat severe asthma in adults and children aged 12 years and older whose asthma is not well-controlled with other treatments. The **Tezspire Patient Assistance Program**, offered by Amgen and AstraZeneca through the Amgen Safety Net Foundation, provides this medication **at no cost** to eligible uninsured or underinsured patients based on financial need.[1][4][5] ## About Tezspire **Tezspire** is a biologic therapy administered by subcutaneous injection every 4 weeks, typically in a doctor's office or at home under medical supervision. It targets an upstream molecule called TSLP (thymic stromal lymphopoietin) to reduce inflammation in the airways, helping prevent asthma attacks and improve breathing. Unlike many asthma drugs that focus on specific pathways like eosinophils or IgE, Tezspire works broadly, making it suitable for patients with severe asthma regardless of biomarker status.[2][4] This guide explains how to access Tezspire for free through the Patient Assistance Program (PAP). It's designed for patients, caregivers, and healthcare providers to navigate eligibility, applications, and support smoothly. ## Who Qualifies? The program is **needs-based** and targets patients who lack adequate insurance coverage for Tezspire. Key qualifiers include: - **Uninsured patients** with household income at or below a percentage of the Federal Poverty Level (FPL). - **Medicare Part B patients** without supplemental insurance. - **Underinsured patients** whose insurance doesn't fully cover the medication may also qualify on a case-by-case basis.[1][4][5] U.S. residents (including Puerto Rico) are eligible. You must agree not to seek reimbursement from insurance or government programs for Tezspire received through the program and notify them of any changes in income or insurance within 30 days.[1] ## Income Eligibility Breakdown Eligibility hinges on household income relative to the **Federal Poverty Level (FPL)**, though exact percentages (e.g., 400% FPL) aren't specified publicly and require application review. The program verifies income to ensure support reaches those in greatest need.[5] Here's a general **2026 FPL reference table** for context (actuals updated annually by HHS; check current guidelines): | Household Size | 100% FPL | 300% FPL | 400% FPL | |---------------|----------|----------|----------| | 1 person | $15,060 | $45,180 | $60,240 | | 2 people | $20,440 | $61,320 | $81,760 | | 3 people | $25,820 | $77,460 | $103,280| | 4 people | $31,200 | $93,600 | $124,800| | +1 person | +$5,380 | +$16,140| +$21,520| *Add $5,380 (100% FPL) per additional person.* Program likely uses up to 400-500% FPL, but submit for verification.[5] ## Insurance Requirements - **Uninsured**: Fully eligible if income-qualified.[4] - **Medicare Part B**: Eligible without supplemental coverage; notify if enrolling in Part D.[1][4] - **Medicare/Medicaid**: Generally ineligible if covered; program is for gaps.[4] - **Commercial/Private Insurance**: Underinsured may qualify if high out-of-pocket costs; co-pay programs like TEZSPIRE Together exist separately for commercial plans.[3] No coverage required, but disclose all insurance details accurately.[1] ## Step-by-Step Application Process 1. **Contact for Help**: Call **1-888-897-7473** (Mon-Fri, 8 AM-8 PM ET) to discuss eligibility and get the form.[2][4] 2. **Download/Request Form**: Obtain the Patient Assistance Program Application (4 pages).[1] 3. **Patient Completes Pages 1-3**: Provide personal info, income proof, residency, insurance details. Sign and date **personally** (no e-signatures).[1] 4. **Physician Completes Page 4**: Prescription and signature required.[1] 5. **Gather Documents**: - Proof of income (tax returns, pay stubs, W-2s). - Proof of residency (utility bill, lease). - Insurance info (cards, denial letters). - Completed form with signatures.[1][4] 6. **Fax to 1-888-388-6016**: Physician faxes the full packet.[1][4] ## Timeline and Delivery Processing time isn't specified but typically 2-4 weeks for similar programs; call for status. Once approved, Tezspire is **shipped free** to your home or physician's office. Reauthorization is required periodically—your doctor will handle renewals.[1][4] ## Alternatives if Denied - **Appeal**: Contact 1-888-897-7473 with updated docs.[2] - **Co-Pay Program**: TEZSPIRE Together for commercial insurance ($0/dose, up to $100/month admin).[3] - **Amgen SupportPlus**: Broader resources for any insurance.[2] - **Other PAPs**: Check RxAssist.org or NeedyMeds for asthma options.[5] - **State Programs**: Medicaid expansion or charity care. No biosimilars available for Tezspire currently.[4] ## Refills and Ongoing Support Track shipments and notify of changes. Reauthorization ensures continued eligibility. ## Disclaimer This guide is for informational purposes based on available program details as of 2026. Eligibility isn't guaranteed; the Amgen Safety Net Foundation may change/terminate the program. Consult your doctor and call 1-888-897-7473 for personalized advice. Do not sell/trade medication. Program for U.S. residents only.

Program information last verified: March 30, 2026