Tegsedi

Indicated For

hATTR polyneuropathy, hereditary transthyretin-mediated amyloidosis

About This Medication

# Tegsedi Patient Assistance Guide: Getting Your Medication at Low Cost ## About Tegsedi Tegsedi (inotersen) is a prescription medication used to treat hereditary transthyresin-mediated amyloidosis (hATTR), a rare genetic condition that causes nerve damage (polyneuropathy). This guide explains how to access Tegsedi affordably if you're struggling with medication costs. ## Important Update: No Active Manufacturer Program Ionis Pharmaceuticals, the maker of Tegsedi, does not currently operate an active prescription assistance program (PAP) for this medication. This means you cannot apply directly to the manufacturer for free or reduced-cost medication. However, you still have options to reduce your costs through other assistance programs and resources explained below. ## How to Get Tegsedi at Lower Cost ### Option 1: Insurance Coverage Your primary path to affordability is through your health insurance plan: - **Contact your insurance company** to confirm Tegsedi coverage and your out-of-pocket costs - Ask about your plan's formulary status (whether Tegsedi is covered) - Request information about prior authorization requirements - Inquire about copay assistance programs your insurance may offer - Insurance coverage rules vary significantly by plan type and employer ### Option 2: Patient Assistance Through Your Healthcare Provider Your doctor's office may have access to: - **Hospital financial assistance programs** if you receive treatment at a medical center - **Patient navigator services** that specialize in finding low-cost medication options - **Specialty pharmacy programs** that sometimes offer cost reduction tools - **Clinical trial opportunities** that may provide medication at no cost ### Option 3: Non-Profit and Government Resources Several organizations offer medication assistance regardless of manufacturer programs: - **Partnership for Prescription Assistance** (pparx.org): Searchable database of all available assistance programs - **NeedyMeds.org**: Directory of free or low-cost medication programs - **State pharmaceutical assistance programs**: Many states offer programs for residents with income below certain thresholds - **Rare disease organizations**: Ask your doctor about disease-specific nonprofits that may help with Tegsedi costs ## Income Eligibility While no active manufacturer program exists, income-based assistance through other sources typically follows these general guidelines: - Income limits **vary by program and state** - Most programs serve individuals and families earning between 100% and 400% of the Federal Poverty Level - 2024 Federal Poverty Level: approximately $15,000 individual / $31,000 family of four - Your specific eligibility depends on which program you apply to **Important**: Contact each program directly to confirm current income requirements. ## What You'll Need to Apply When seeking assistance through non-manufacturer programs, typically gather: 1. **Proof of income**: Recent tax returns, pay stubs, or benefit statements 2. **Valid prescription**: Written prescription for Tegsedi from your doctor 3. **Proof of insurance status**: Insurance card or denial letter 4. **Identification**: Government-issued ID 5. **Financial information**: Bank statements or rent/mortgage documentation ## How to Get Started: 4-Step Process **Step 1**: Contact your insurance company to understand your coverage options and copay costs **Step 2**: Ask your doctor's office about patient assistance services and specialty pharmacy programs **Step 3**: Visit pparx.org or NeedyMeds.org to search for available programs matching your situation **Step 4**: Apply to programs you qualify for, following each program's specific application instructions ## Timeline for Assistance Processing times vary widely: - **Insurance authorization**: 1-2 weeks typically - **Non-profit assistance programs**: 1-4 weeks after complete application - **State programs**: 2-6 weeks depending on state Start the process as soon as possible to minimize delays in treatment. ## What If You're Denied? If denied assistance: - Ask specifically why you were denied - Request if reapplying with additional documentation is possible - Try alternative programs (income limits and rules differ) - Contact your doctor's office for other solutions - Discuss payment plans with your pharmacy ## Need Help? If you're unsure where to start: 1. Call your doctor's office and ask for the patient assistance coordinator 2. Call your insurance company's member services number (on your insurance card) 3. Contact the Partnership for Prescription Assistance: 1-888-477-2669 4. Ask about a social worker or case manager at your treatment facility Don't delay seeking Tegsedi due to cost concerns—multiple resources exist to help you access this important medication.

Program information last verified: March 25, 2026