TALZENNA

Indicated For

BRCA+ HER2- breast cancer

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get TALZENNA (talazoparib) at Low or No Cost TALZENNA (talazoparib) is a prescription medication used to treat certain types of cancer, and the **Pfizer Patient Assistance Program** offers it at low or no cost to eligible patients who meet income and insurance criteria. This guide explains everything you need to know about qualifying, applying, and receiving your medication. ## About TALZENNA (talazoparib) TALZENNA is an oral capsule prescribed for adults with **deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) HER2-negative locally advanced or metastatic breast cancer**. It works as a PARP inhibitor, helping to stop cancer cells from growing by blocking enzymes they need to repair their DNA. Always take it exactly as your doctor prescribes, typically once daily with or without food. Common side effects may include fatigue, anemia, nausea, and decreased blood cell counts—discuss these with your healthcare provider. This program provides free TALZENNA through Pfizer Inc. or the Pfizer Patient Assistance Foundation for those who qualify[1][2][8]. ## Who Qualifies for the Program? The Pfizer Patient Assistance Program is designed for patients struggling to afford their Pfizer medications, like TALZENNA. Key eligibility requirements include: - **Age and Residency**: You must be 18 years or older and reside in the U.S. or a U.S. territory with a valid U.S. address. No proof of citizenship is required[2][8]. - **Prescription**: You need a valid prescription from a U.S.-licensed healthcare provider for outpatient use, and an FDA-approved diagnosis[3][10]. - **Income Limits**: Household income must be at or below **500% of the Federal Poverty Level (FPL)**, adjusted for family size[8]. - **Insurance Status**: Uninsured patients or those with government insurance (like Medicare or Medicaid) who can't afford costs after exhausting other resources. **Commercially insured patients are not eligible**[2][3][10]. ## Income Eligibility Breakdown Eligibility is based on pre-tax household income compared to 500% FPL. Use the table below for 2026 guidelines (FPL updates annually; check www.PfizerRxPathways.com for latest figures). For example, a family of 4 at 500% FPL might have a limit around $150,000—confirm exact amounts during application. | Household Size | 100% FPL (approx.) | 500% FPL Limit (approx.) | |----------------|---------------------|---------------------------| | 1 (Individual) | $15,060 | $75,300 | | 2 (Couple) | $20,440 | $102,200 | | 3 | $25,820 | $129,100 | | 4 | $31,200 | $156,000 | | +1 per member | +$5,380 | +$26,900 | *Notes: Figures are estimates based on 2025 FPL; actuals adjust yearly. Include all household income sources. Provide proof like tax returns or pay stubs[2][4].* ## Insurance Requirements - **Uninsured**: Fully eligible if other criteria met. - **Medicare/Medicaid**: Eligible after trying other assistance, like Medicare Prescription Payment Plan. Medicare Part D patients must document enrollment in this plan and attest they can't afford costs[7][8]. - **Commercial Insurance**: Not eligible—explore co-pay cards first via Pfizer Oncology Together[6][8]. - Patients with insurer denials (after appeals) may qualify if uninsured effectively[8]. ## Step-by-Step Application Process 1. **Check Eligibility**: Visit www.PfizerRxPathways.com, use the Program Finder, and enter "TALZENNA"[1][2]. 2. **Gather Documents**: - Completed enrollment form (patient and doctor sections). - Proof of income: 1040 tax return (pages 1-2), W-2, pay stubs (2 recent), SSA-1099, etc.[2][4]. - Insurance cards (front/back), Medicare details if applicable. - Prescription from your doctor[8][10]. 3. **Apply Online or Manually**: - **Preferred: Pfizer PAP Connect** at www.pfizerrxpathways.com/pfizer-pap-connect. Upload docs, track status[1][5]. - **Phone**: Call (800) 505-4426 for help or forms[program details]. - **Mail/Fax**: Send to Pfizer Patient Assistance Program, P.O. Box 66585, St. Louis, MO 63166-6585 or fax 866-470-1748/1-877-548-1734[4][10]. 4. **Doctor's Role**: Your prescriber completes certification, confirms diagnosis, and may submit[1][10]. 5. **Sign Consents**: Authorize income verification (electronic optional) and certify inability to pay[3][8]. Applications support multiple methods for accessibility[program details]. ## Timeline and Delivery Expect notification within **2-3 weeks** of submission, sometimes faster (3 business days via PAP Connect)[1][4][9]. If approved, receive a letter with enrollment term (typically 1 year) and shipment details. Medication ships **directly to your home** at no cost[program details][4]. Reauthorization is required annually[program details]. ## Alternatives if Denied or Ineligible - **Appeal**: Contact the program at (800) 505-4426 to review denial reasons, like income or insurance[1]. - **Other Pfizer Programs**: Pfizer Oncology Together for co-pay help if commercially insured[6]. - **Government Aid**: Apply for Medicaid, Medicare Extra Help, or state programs. - **Non-Profit**: NeedyMeds.org, RxAssist.org, or PAN Foundation. - **Manufacturer Alternatives**: No biosimilars for TALZENNA listed[program details]. - **Discount Cards**: GoodRx for uninsured, though less ideal for free programs. ## Refills and Ongoing Support Once enrolled, request refills via PAP Connect or phone. Reapply before expiration—reauthorization needs updated income proof[program details][5]. ## Important Disclaimer This guide is for informational purposes based on available program details as of 2026 and does not guarantee eligibility or coverage. Rules can change; always verify at www.PfizerRxPathways.com or by calling (800) 505-4426. Consult your doctor for medical advice. Pfizer Inc. and the Pfizer Patient Assistance Foundation reserve rights to modify or end the program. Not legal or financial advice—seek professional help for your situation[1][2][3]. (Word count: 1028)

Program information last verified: March 30, 2026