TALZENNA

Indicated For

breast cancer, prostate cancer

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get TALZENNA (talazoparib) at Low or No Cost TALZENNA (talazoparib) is a prescription medication used to treat certain types of advanced breast cancer in adults with specific genetic changes, such as harmful or suspected harmful germline BRCA mutations. The **Pfizer Patient Assistance Program** offers TALZENNA at low or no cost to eligible uninsured patients who meet strict income and other requirements, helping those who cannot afford their medication[1][5]. ## About TALZENNA (talazoparib) TALZENNA is an oral capsule taken once daily, classified as a PARP inhibitor. It works by blocking enzymes that cancer cells use to repair their DNA, slowing or stopping cancer growth. It is FDA-approved for adults with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) HER2-negative locally advanced or metastatic breast cancer. Always take it exactly as prescribed by your doctor, typically with or without food, and do not crush or chew the capsules. Common side effects include fatigue, anemia, nausea, decreased appetite, and hair loss—discuss any concerns with your healthcare provider. This program provides free medication to qualifying patients but does not cover doctor visits, tests, or other costs[3][5]. ## Who Qualifies for the Program? Eligibility focuses on financial need, residency, insurance status, and residency in the U.S. Key requirements include: - **Residency**: Must live in the U.S. or a U.S. territory and be treated by a U.S.-licensed healthcare provider. - **Age**: 18 years or older. - **Diagnosis**: FDA-approved indication with a valid prescription. - **Income**: Household pre-tax income at or below **500% of the Federal Poverty Level (FPL)**, adjusted for family size. Patients must not qualify for Medicaid. - **Insurance**: Uninsured or insured through government programs but unable to afford costs; **not eligible** if enrolled in Medicare, Medicaid, or commercial insurance[1][4][5][7]. Additional notes: Medicare Part D patients may qualify if enrolled in the Medicare Prescription Payment Plan, have not met their out-of-pocket maximum, and attest to inability to pay[3][5]. ## Income Eligibility Breakdown Income limits are based on **500% FPL** for your household size. Use your total pre-tax annual household income. Here's a table with approximate 2026 guidelines (FPL updates annually; verify current levels at application): | Household Size | Max Annual Income (500% FPL) | |----------------|------------------------------| | 1 (Individual) | $75,300 | | 2 (Couple) | $101,500 | | 3 | $127,600 | | 4 | $153,800 | | +1 person | Add ~$26,200 per person | *Notes*: Provide proof like tax returns (1040), W-2s, pay stubs, or Social Security statements. Electronic verification is optional but speeds processing[2][3]. ## Insurance Requirements - **Uninsured patients** are primary candidates. - **Government insurance**: May qualify if you do not qualify for Medicaid and cannot afford costs post-prior authorization. Medicare patients must enroll in the Medicare Prescription Payment Plan and confirm unmet out-of-pocket maximums. - **Ineligible**: Anyone with commercial insurance (job-based or employer plans), active Medicare/Medicaid enrollment, or sufficient coverage[5][7]. Work with your doctor and insurer first to understand true costs after prior authorization. ## Step-by-Step Application Process 1. **Check Eligibility**: Visit www.PfizerRxPathways.com, use the Program Finder, and enter "TALZENNA". Confirm you qualify[1][7]. 2. **Gather Documents**: - Valid prescription for TALZENNA. - Proof of income (e.g., 1040 tax return pages 1-2, W-2s, two recent pay stubs, SSA-1099). - Proof of residency (e.g., utility bill, driver's license). - Insurance details (front/back of cards if applicable); Medicare ID if relevant[2][3][4]. 3. **Complete Application**: - **Online (preferred)**: Use Pfizer PAP Connect at www.pfizerpapconnect.com or www.PfizerRxPathways.com. Upload documents, track status[1][6][8]. - **Phone**: Call (877) 744-5675, Mon-Fri 8am-8pm ET for help or manual process[1][4]. - **Fax/Mail**: Doctor completes sections; fax to 1-877-548-1734[3]. 4. **Doctor's Role**: Prescriber fills out clinical sections, signs, and provides NPI/license[3]. 5. **Sign and Submit**: Patient signs consents for income verification and program use[3]. Applications support multiple methods for accessibility[program details]. ## Timeline and Delivery - **Processing**: 2-3 weeks for enrollment notification; online reviews in 3 business days[1][8]. - **Delivery**: Medication shipped free directly to you (your home address)[program details]. - **Supply**: Typically 1-3 months per shipment; **reauthorization required** annually or as needed[program details][3]. ## Alternatives if Denied or Ineligible - **Pfizer Oncology Together**: Copay assistance for commercially insured (visit PfizerRxPathways.com). - **Other PAPs**: Check NeedyMeds.org or RxAssist.org for TALZENNA alternatives. - **State Programs**: Local Medicaid waivers or charity care. - **Manufacturer Copay Cards**: If insured, ask your doctor. - **Generic/Biosimilars**: None currently available[program details]. Reapply if circumstances change. ## Important Disclaimer This guide is for informational purposes based on publicly available program details as of 2026. Eligibility, income levels, and rules can change—always verify at www.PfizerRxPathways.com or by calling (877) 744-5675. Pfizer makes final decisions. This is not medical advice; consult your doctor for TALZENNA suitability. Program does not guarantee approval and excludes commercial insurance. Keep records of all submissions.

Program information last verified: March 25, 2026