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Takhzyro

Generic: lanadelumab

Manufacturer: Takeda  ·  Program: Takeda Help at Hand

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Eligibility Criteria

Insurance Requirement

Must be uninsured, underinsured, or have commercial insurance that does not cover the medication. Patients with government insurance are generally ineligible for co-pay cards but may qualify for PAP based on clinical and financial need.

Residency

U.S. resident or U.S. territory resident

Income Threshold

Up to 500% FPL

Individual Income Limit

$75,300/year

Calculated based on 500% FPL for rare disease medications under Takeda Help at Hand program.

Program Information

Processing Time

2-4 business days

Delivery Method

shipped to patient

Application Method

Multiple

Reauthorization

Required — annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • Completed application form with physician signature
  • Proof of household income (e.g., 1040, W-2, or recent pay stubs)
  • Prescription for Takhzyro

Indicated For

Hereditary Angioedema (HAE) Type I and Type II

About This Medication

# Takeda Help at Hand: Your Guide to Getting Takhzyro at Low or No Cost ## Who Qualifies for the Takeda Help at Hand? If you have been prescribed Takhzyro (lanadelumab) and are struggling with the cost, you may be able to get it free or at a reduced cost through the **Takeda Help at Hand** patient assistance program. This program is designed specifically for patients who need financial support to access Takhzyro. For a single-person household, your annual income must be at or below **$75,300** to qualify. In terms of insurance, you must be uninsured, underinsured, or have commercial insurance that does not adequately cover this medication. If you have government-funded insurance such as Medicare or Medicaid, different rules apply, which are explained in detail below. --- ## About Takhzyro (lanadelumab) Takhzyro is a prescription injectable medication made by Takeda. It is FDA-approved for the prevention of hereditary angioedema (HAE) attacks in adults and pediatric patients 12 years and older who have HAE Type I or Type II. Takhzyro belongs to a class of drugs called plasma kallikrein inhibitors and works as a monoclonal antibody. Without insurance or financial assistance, the list price of Takhzyro can reach tens of thousands of dollars per month, placing it out of reach for many patients. The Takeda Help at Hand program exists to help bridge that gap for eligible individuals. --- ## Income Eligibility: Full Breakdown Takeda Help at Hand uses income thresholds based on approximately 500% of the Federal Poverty Level, which is a standard used for rare disease medications. The income limits by household size are as follows: | Household Size | Max Annual Income | |---|---| | 1 person | $75,300 | | 2 persons | $102,200 | | 3 persons | $129,100 | | 4 persons | $156,000 | Your income is typically verified using your most recent federal tax return (Form 1040 or W-2) or three months of recent pay stubs. If your household size is larger than four people, contact Takeda Help at Hand directly to ask about your specific situation, as the program may have flexibility beyond the published table. If your income is above these limits, you may not qualify for free medication through the patient assistance program. However, you may still be eligible for the Takhzyro co-pay savings card if you have commercial insurance. Other options are outlined in the "Alternatives" section below. Do not assume you are ineligible without speaking with a program representative — income from certain sources may be calculated differently, and it is always worth asking. --- ## Insurance Requirements Explained Your insurance situation plays a major role in how Takeda Help at Hand can help you: - **If you are uninsured:** You are a strong candidate for the patient assistance program (PAP). If you meet the income requirements, you may receive Takhzyro at no cost through the program. - **If you have Medicare Part D:** You are generally not eligible for the manufacturer co-pay savings card. However, you may still qualify for the patient assistance program based on your clinical need and financial situation. Contact the program directly at **(800) 830-9361** to discuss your options. - **If you have private insurance that covers less than 50% of the cost:** You may be considered underinsured and could qualify for the PAP. You may also be eligible for the co-pay savings card to help cover your out-of-pocket costs under your commercial plan. - **If you have Medicaid:** Medicaid patients are generally excluded from manufacturer co-pay cards. You may still be reviewed for the PAP on a case-by-case basis depending on your state and clinical need. Ask a program representative about your specific situation. --- ## Step-by-Step: How to Apply Follow these steps to apply for Takeda Help at Hand: 1. **Gather your documents.** You will need a completed application form with your physician's signature, proof of household income (such as your most recent Form 1040, W-2, or three months of pay stubs), and a valid prescription for Takhzyro. 2. **Choose your application method.** You can apply online, by phone, or by fax. - **Online:** Visit [https://www.takedahelpathand.com/](https://www.takedahelpathand.com/) to complete and submit your application digitally. - **By phone:** Call **(800) 830-9361** to speak with a program representative who can walk you through the process. - **By fax:** Send your completed application and supporting documents to **(866) 825-3321**. 3. **Have your doctor complete their portion.** The application requires a physician signature, so make sure your prescribing doctor is aware and prepared to sign. 4. **Submit all required documents together.** Incomplete applications can delay processing, so confirm everything is included before submitting. 5. **Wait for a decision.** Processing typically takes **2 to 4 business days** after your complete application is received. 6. **Confirm approval and arrange delivery.** Once approved, you will be notified and your medication will be arranged for shipment directly to your home. --- ## What to Expect: Timeline and Delivery After you submit a complete application, expect a decision within **2 to 4 business days**. You will typically be notified of approval by phone or mail. If approved, Takhzyro is shipped directly to your home — you do not need to pick it up at a pharmacy or your doctor's office. You should not need to take any additional steps at delivery beyond receiving the package. Because Takhzyro is an injectable medication, make sure you have spoken with your doctor or nurse about proper storage and administration before your first shipment arrives. Your enrollment in the program must be **renewed annually**. You will need to resubmit income documentation and an updated application each year to continue receiving assistance. Plan ahead so there is no gap in your medication supply. --- ## Alternatives If You Don't Qualify If you do not qualify for the Takeda Help at Hand patient assistance program, you still have options: 1. **Biosimilars:** There are currently no FDA-approved biosimilar alternatives to Takhzyro. This option is not available at this time. 2. **Manufacturer co-pay savings card:** If you have commercial insurance, you may be eligible for the Takhzyro co-pay program, which can reduce your out-of-pocket costs. Learn more at [https://www.takhzyro.com/patient-support/copay-program](https://www.takhzyro.com/patient-support/copay-program). 3. **State Pharmaceutical Assistance Programs (SPAPs):** Many states offer programs that help residents pay for high-cost medications. Eligibility and benefits vary by state. Contact your state's department of health or aging to ask what may be available to you. 4. **NeedyMeds.org:** This free, independent database lists hundreds of patient assistance programs and drug discount options. Visit [https://www.needymeds.org](https://www.needymeds.org) to search by medication name and explore additional resources that may help cover your costs. --- > *This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Takeda. Program terms may change — verify current requirements at [https://www.takhzyro.com/patient-support](https://www.takhzyro.com/patient-support) before applying.* ---

Program information last verified: February 27, 2026

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