Synribo

Indicated For

Chronic Myeloid Leukemia (CML), TKI-resistant

About This Medication

# Teva Cares Foundation Patient Assistance Program Guide: How to Get Synribo (omacetaxine mepesuccinate) at Low or No Cost Synribo (omacetaxine mepesuccinate) is a prescription medication used to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) who have resistance or intolerance to two or more tyrosine kinase inhibitors (TKIs).[1][4][10] The **Teva Cares Foundation Patient Assistance Program** provides eligible patients with Teva medicines, including Synribo, at no cost if they meet specific U.S. residency, insurance, income, and prescription requirements.[2][3][6] ## About Synribo **Synribo** is injected subcutaneously and is FDA-approved for home administration after preparation by a healthcare professional.[1][4] It targets CML patients who no longer respond to or tolerate standard TKIs. Treatment involves cycles of twice-daily injections for 14 days followed by 28-day rest periods, with adjustments based on response.[10] Teva's **SYNCare program** complements assistance by offering home delivery of prepared doses via partners like Diplomat Pharmacy or Coram Specialty Pharmacy, supplies for self-administration, injection training, educational resources, and 24/7 support.[1][4][7] **Important safety note**: Synribo must be prepared in a healthcare facility; patients or caregivers administer under guidance. Always follow your doctor's instructions and report side effects like low blood counts, infections, or bleeding.[1][10] ## Who Qualifies for Teva Cares? To qualify, you must: - Reside in the U.S. or its territories.[6] - Have a valid U.S. prescription for a covered Teva medicine like Synribo.[6] - Meet income eligibility (specific Federal Poverty Level (FPL) thresholds not detailed publicly; program assesses household income).[2][6] - Satisfy insurance criteria: uninsured, underinsured, or with coverage that doesn't cover the full cost. No participation in alternative funding programs that require Teva Cares enrollment.[2][6] Patients with income below 150% FPL need proof of denial from Medicare's Low-Income Subsidy (LIS/Extra Help).[6] The program is free—no fees for application, enrollment, or delivery.[2] ## Income Eligibility Breakdown Teva Cares uses household income relative to **FPL**, but exact percentages (e.g., 400%, 500%) are not specified in public details—contact the program for your situation.[2][6] Here's a general guide based on 2026 FPL (adjusts annually; verify current levels): | Household Size | 400% FPL Example (Annual Income) | 500% FPL Example (Annual Income) | Notes | |----------------|---------------------------------|----------------------------------|-------| | 1 (Individual) | ~$60,320 | ~$75,400 | Proof of LIS denial if <150% FPL [6] | | 2 (Couple) | ~$81,760 | ~$102,200 | Add ~$21,440 per extra person | | 3 | ~$103,200 | ~$129,000 | Household income assessed | | 4 | ~$124,640 | ~$155,800 | Contact for exact thresholds | *Examples approximate; program confirms eligibility. No employer/insurance ties to alternative programs allowed.[2]* ## Insurance Requirements Provide details of any health insurance or prescription coverage.[6] Uninsured applicants qualify if other criteria met. Insured patients may be eligible if coverage gaps exist, but prior authorization denial letters are required for incomplete applications.[6] Medicare patients under 150% FPL must show LIS/Extra Help denial.[6] Teva Cares bridges gaps but excludes those in conflicting funding setups.[2] ## Step-by-Step Application Process 1. **Verify eligibility**: Review covered medicines on tevacares.org and check residency, insurance, income, prescription.[6] 2. **Gather documents**: Prescription, proof of income (tax returns, pay stubs), insurance details, LIS denial if applicable.[6] 3. **Complete application**: Online at tevacares.org or call **877-237-4881** (Mon-Fri, 9AM-8PM ET) / **(844) 796-2273** for Synribo/SYNCare support.[2][6] 4. **Submit prescription**: From U.S. licensed provider; include SYNRIBO Prescription and Services Request Form for SYNCare.[4] 5. **Healthcare provider role**: Doctor may need to submit or coordinate with pharmacy partners like Coram.[4] 6. **Wait for approval**: Program reviews; no processing time specified—call for status.[2] No fees involved; avoid third-party services charging for help.[2] ## Timeline and Delivery Processing timelines not publicly detailed—expect several weeks; call **877-237-4881** for updates.[2] Once approved, Synribo ships free via SYNCare partners directly to your door with prepared doses and supplies.[1][4] Home administration supported with training and 24/7 hotline.[1] Refills handled through prescription renewals and Coram/Diplomat.[4] ## Alternatives if Denied - **Other Teva programs**: Call 888-TEVA USA (888-838-2872) for options.[3] - **SYNCare alone**: For home support even if not fully free.[1][4] - **PAN Foundation or Good Days**: Financial aid for Synribo.[8] - **State assistance or generic alternatives**: Consult doctor; no biosimilars listed.[8][10] - **Reapply**: Fix issues like missing docs and resubmit.[6] ## Disclaimer This guide is for informational purposes based on publicly available data as of 2026.[1][2][3][4][6] Eligibility, terms, and availability can change—always verify with Teva Cares at **877-237-4881** or tevacares.org. Not medical advice; consult your healthcare provider for treatment decisions. Teva Cares is independent; SYNCare is separate support. Program excludes certain insurances/funding conflicts.[2] Word count: 942.

Program information last verified: March 30, 2026