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Oncology

Synribo

Generic: omacetaxine mepesuccinate

Manufacturer: Teva  ·  Program:

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Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

See program details

Residency

US residency required

Income Threshold

Up to 300% FPL

Individual Income Limit

$43,740/year

Income limits for generic drugs vary; call to verify

Program Information

Processing Time

2–3 weeks

Delivery Method

shipped to patient or physician office

Application Method

Multiple

Indicated for

Chronic Myeloid Leukemia (CML), TKI-resistant

About This Medication

Teva Cares Foundation Patient Assistance Program Guide: How to Get Synribo (omacetaxine mepesuccinate) at Low or No Cost

Synribo (omacetaxine mepesuccinate) is a prescription medication used to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) who have resistance or intolerance to two or more tyrosine kinase inhibitors (TKIs).[1][4][10] The Teva Cares Foundation Patient Assistance Program provides eligible patients with Teva medicines, including Synribo, at no cost if they meet specific U.S. residency, insurance, income, and prescription requirements.[2][3][6]

About Synribo

Synribo is injected subcutaneously and is FDA-approved for home administration after preparation by a healthcare professional.[1][4] It targets CML patients who no longer respond to or tolerate standard TKIs. Treatment involves cycles of twice-daily injections for 14 days followed by 28-day rest periods, with adjustments based on response.[10] Teva's SYNCare program complements assistance by offering home delivery of prepared doses via partners like Diplomat Pharmacy or Coram Specialty Pharmacy, supplies for self-administration, injection training, educational resources, and 24/7 support.[1][4][7]

Important safety note: Synribo must be prepared in a healthcare facility; patients or caregivers administer under guidance. Always follow your doctor's instructions and report side effects like low blood counts, infections, or bleeding.[1][10]

Who Qualifies for Teva Cares?

To qualify, you must:

  • Reside in the U.S. or its territories.[6]
  • Have a valid U.S. prescription for a covered Teva medicine like Synribo.[6]
  • Meet income eligibility (specific Federal Poverty Level (FPL) thresholds not detailed publicly; program assesses household income).[2][6]
  • Satisfy insurance criteria: uninsured, underinsured, or with coverage that doesn't cover the full cost. No participation in alternative funding programs that require Teva Cares enrollment.[2][6]

Patients with income below 150% FPL need proof of denial from Medicare's Low-Income Subsidy (LIS/Extra Help).[6] The program is free—no fees for application, enrollment, or delivery.[2]

Income Eligibility Breakdown

Teva Cares uses household income relative to FPL, but exact percentages (e.g., 400%, 500%) are not specified in public details—contact the program for your situation.[2][6] Here's a general guide based on 2026 FPL (adjusts annually; verify current levels):

Household Size400% FPL Example (Annual Income)500% FPL Example (Annual Income)Notes
1 (Individual)~$60,320~$75,400Proof of LIS denial if <150% FPL [6]
2 (Couple)~$81,760~$102,200Add ~$21,440 per extra person
3~$103,200~$129,000Household income assessed
4~$124,640~$155,800Contact for exact thresholds

Examples approximate; program confirms eligibility. No employer/insurance ties to alternative programs allowed.[2]

Insurance Requirements

Provide details of any health insurance or prescription coverage.[6] Uninsured applicants qualify if other criteria met. Insured patients may be eligible if coverage gaps exist, but prior authorization denial letters are required for incomplete applications.[6] Medicare patients under 150% FPL must show LIS/Extra Help denial.[6] Teva Cares bridges gaps but excludes those in conflicting funding setups.[2]

Step-by-Step Application Process

  1. Verify eligibility: Review covered medicines on tevacares.org and check residency, insurance, income, prescription.[6]
  2. Gather documents: Prescription, proof of income (tax returns, pay stubs), insurance details, LIS denial if applicable.[6]
  3. Complete application: Online at tevacares.org or call 877-237-4881 (Mon-Fri, 9AM-8PM ET) / (844) 796-2273 for Synribo/SYNCare support.[2][6]
  4. Submit prescription: From U.S. licensed provider; include SYNRIBO Prescription and Services Request Form for SYNCare.[4]
  5. Healthcare provider role: Doctor may need to submit or coordinate with pharmacy partners like Coram.[4]
  6. Wait for approval: Program reviews; no processing time specified—call for status.[2]

No fees involved; avoid third-party services charging for help.[2]

Timeline and Delivery

Processing timelines not publicly detailed—expect several weeks; call 877-237-4881 for updates.[2] Once approved, Synribo ships free via SYNCare partners directly to your door with prepared doses and supplies.[1][4] Home administration supported with training and 24/7 hotline.[1] Refills handled through prescription renewals and Coram/Diplomat.[4]

Alternatives if Denied

  • Other Teva programs: Call 888-TEVA USA (888-838-2872) for options.[3]
  • SYNCare alone: For home support even if not fully free.[1][4]
  • PAN Foundation or Good Days: Financial aid for Synribo.[8]
  • State assistance or generic alternatives: Consult doctor; no biosimilars listed.[8][10]
  • Reapply: Fix issues like missing docs and resubmit.[6]

Disclaimer

This guide is for informational purposes based on publicly available data as of 2026.[1][2][3][4][6] Eligibility, terms, and availability can change—always verify with Teva Cares at 877-237-4881 or tevacares.org. Not medical advice; consult your healthcare provider for treatment decisions. Teva Cares is independent; SYNCare is separate support. Program excludes certain insurances/funding conflicts.[2] Word count: 942.

Program information last verified: March 30, 2026

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