Synagis

Indicated For

RSV prophylaxis in premature infants, high-risk pediatric patients

About This Medication

# Synagis Patient Assistance Program Guide: How to Get Synagis (palivizumab) at Low or No Cost Synagis (palivizumab) is a monoclonal antibody injection used to prevent serious lower respiratory tract disease caused by respiratory syncytial virus (RSV) in high-risk infants and young children, such as those born prematurely or with certain lung or heart conditions.[4][7] This patient-friendly guide explains the **Synagis Patient Assistance Program** from Sobi and related copay support options, helping families access this critical medication during RSV season (typically November through March) when costs can be a barrier.[1][2][7] ## About Synagis and Why It's Important **Synagis** is given as a monthly intramuscular injection, usually up to **5 doses** during the RSV season, at 15 mg/kg per dose.[4][6][7] It's not a treatment for active RSV infection but prevents severe illness in vulnerable babies, like those born before 29 weeks gestation or under 12 months old at RSV season start, children with chronic lung disease, or those with hemodynamically significant congenital heart disease.[4][7] Administered by healthcare providers, it's most effective when started at the beginning of RSV season, as defined by CDC surveillance.[4][6] RSV is a common virus that can lead to hospitalization in high-risk infants. Without prevention, these children face higher risks of bronchiolitis or pneumonia. Synagis has been FDA-approved since 1998 for this purpose and follows American Academy of Pediatrics (AAP) guidelines.[4][10] ## Who Qualifies for Assistance? There are two main Sobi-related programs for Synagis: 1. **Synagis Patient Assistance Program (PAP)**: For **uninsured** patients. Must be a US citizen treated by a US doctor, meet undisclosed income guidelines, and require prescreening by the doctor's office.[2] 2. **Synagis Copay Assistance Program**: For patients with **commercial insurance** (not Medicare/Medicaid). Helps reduce copays.[1] High-risk status is determined by your doctor based on AAP criteria (e.g., prematurity <29 weeks, bronchopulmonary dysplasia).[4][7][10] Programs do not cover treatment of active RSV or non-approved uses like asthma prevention.[4][9] ## Income Eligibility Breakdown Specific income thresholds are **not publicly disclosed** for the main PAP, requiring prescreening.[2] Here's a summary table based on available program details: | Household Size | Income Threshold | FPL % | Notes | |---------------|------------------|-------|-------| | Individual | Not disclosed | Not specified | Prescreening required via doctor's office.[2] | | Couple | Not disclosed | Not specified | US citizen; no insurance.[2] | | Family of 3 | Not disclosed | Not specified | Income guidelines applied during application.[2] | | Family of 4 | Not disclosed | Not specified | Doctor completes section; patient signs.[2] | Contact the program for personalized eligibility (phone below). Third-party services like Prescription Hope may assist insured/uninsured patients for a $60-70 monthly fee, with broader income guidelines.[5] ## Insurance Requirements - **PAP**: **No insurance** required (uninsured only).[2] - **Copay Program**: **Commercial insurance** mandatory; excludes government insurance like Medicare/Medicaid.[1] If insured, check coverage first—many plans require prior authorization and limit to 5 doses.[6][7][8] Synagis may be billed as medical (doctor's office/hospital) or pharmacy benefit (home administration).[7][8] Programs work alongside insurance but not as a replacement.[5] ## Step-by-Step Application Process 1. **Confirm Eligibility**: Doctor's office calls for **prescreening** (877-480-8082).[2] 2. **Gather Documents**: Doctor fills out their section, signs, attaches DEA/State License copy. Patient completes and signs their section. No full list specified, but proof of no insurance, income, citizenship, and prescription needed.[2] 3. **Submit Application**: Doctor/Office mails to PO Box 222197, Charlotte, NC 28222-2197, or faxes 877-675-6513. Online application available via RxHope.[2] 4. **For Copay Program**: Visit synagishcp.com or call for details; requires commercial insurance verification.[1] 5. **Alternative**: Use services like Prescription Hope (apply online, they handle paperwork for $60/month).[5] Your doctor must prescribe Synagis and oversee administration. ## Timeline and Delivery - **Processing**: After prescreening and paperwork, expect **2-4 weeks** for first delivery (similar to comparable programs).[5] - **Supply**: Up to **30-day supply** per approval, aligned with monthly dosing (every 28 days, max 5 doses).[2][6] - **Delivery**: Ships to **doctor's office** for administration (not directly to home).[2][8] RSV season timing is key—apply early (e.g., before November).[7][8] ## Alternatives if Denied or Ineligible - **Appeal**: Resubmit with additional doctor documentation or contact program.[2] - **Third-Party Help**: Prescription Hope ($60/month, works with insurance).[5] - **State Programs**: Check Medicaid/Medi-Cal for prior auth (e.g., pharmacy or medical claim).[7][8] - **No Biosimilars**: None available.[ ] - **Other PAPs**: RxAssist or RxHope databases for similar support.[3] Consult your doctor for insurance appeals or AAP-guided coverage.[10] ## Important Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Program details can change; always verify with Sobi (877-480-8082) or your healthcare provider. Not medical advice—eligibility not guaranteed. Assistance limited to US residents. For emergencies, seek immediate care. Word count: 1028.

Program information last verified: March 30, 2026