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Symfi Lo

Generic: efavirenz 400mg lamivudine tenofovir disoproxil fumarate

Manufacturer: Viatris  ·  Program:

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Eligibility Criteria

Insurance Requirement

See program details

Residency

US residency required

Income Threshold

Up to 400% FPL

Individual Income Limit

$58,320/year

Income limits vary significantly by drug — call to verify

Program Information

Processing Time

2–3 weeks

Delivery Method

shipped to patient

Application Method

Multiple

Indicated For

HIV-1 infection

About This Medication

# Viatris Patient Assistance Program Patient Guide: How to Get Symfi Lo at Low or No Cost Symfi Lo (efavirenz 400mg/lamivudine/tenofovir disoproxil fumarate) is a prescription medication used to treat HIV infection in adults and children weighing at least 88 pounds (40 kg). The **Viatris Patient Assistance Program (PAP)** offers this and other qualifying medicines **free of charge** to eligible U.S. residents who are uninsured, meet financial need criteria, and have a valid prescription[1][2][3][8]. This guide explains everything you need to know about applying, qualifying, and receiving Symfi Lo through the program. It's designed for patients like you—clear, step-by-step, and easy to follow. Always consult your doctor or pharmacist for personalized advice. ## About Symfi Lo **Symfi Lo** is a fixed-dose combination antiretroviral therapy (ART) tablet containing three active ingredients: efavirenz (400 mg, a non-nucleoside reverse transcriptase inhibitor), lamivudine (a nucleoside reverse transcriptase inhibitor), and tenofovir disoproxil fumarate (a nucleotide reverse transcriptase inhibitor). Taken once daily, it helps control HIV by reducing the viral load, improving immune function, and preventing progression to AIDS. It's approved for treatment-naïve or experienced patients without resistance to these components[8]. Common side effects include dizziness, headache, nausea, fatigue, and sleep disturbances (especially from efavirenz). Serious risks involve liver problems, kidney issues (from tenofovir), lactic acidosis, or immune reconstitution syndrome. Regular blood tests monitor kidney and bone health. Never stop or change your dose without medical guidance, as this can lead to drug resistance[8]. Symfi Lo is manufactured by **Viatris**, which runs the PAP to help patients afford essential HIV treatments like this one[1][2]. ## Who Qualifies for the Viatris PAP? To qualify, you must meet **all** these criteria: - Be a legal resident of the United States (including territories like Puerto Rico)[3][6]. - Be **uninsured** or underinsured with no coverage for the medication[3][6]. - Have a household income below the program's financial thresholds (specific Federal Poverty Level (FPL) percentage not publicly detailed; based on demonstrated financial need)[1][2][4]. - Have a valid prescription from a licensed U.S. healthcare provider for Symfi Lo[2][3]. - Not be enrolled in government programs that cover the drug (full details verified during application)[3]. The program targets those who "otherwise cannot afford their medications," prioritizing low-income patients without insurance[4][6]. ## Income Eligibility Breakdown Exact income thresholds (e.g., % of FPL) are not specified publicly and are assessed case-by-case via proof of income. Applicants must demonstrate financial need, often at or below 400-500% FPL based on similar programs, but Viatris reviews household size and total income[1][4]. Provide recent tax returns, pay stubs, or benefit statements. Here's a general **example table** of common PAP income limits (adjusted for 2026; confirm with Viatris as they vary): | Household Size | Max Annual Income (Approx. 400% FPL) | |----------------|-------------------------------------| | 1 (Individual) | $60,000 | | 2 (Couple) | $81,000 | | 3 | $102,000 | | 4 | $123,000 | *Notes: Add ~$21,000 per additional member. These are illustrative; Viatris determines exact eligibility. Assets may also be considered[1][2][4].* ## Insurance Requirements You must be **uninsured** for the requested medication—meaning no private insurance, Medicare, Medicaid, or other coverage pays for Symfi Lo[3][6]. Viatris verifies your insurance status and may contact your provider. If underinsured (e.g., high copays), you might still qualify if coverage is denied. Medicare Part D patients are typically ineligible, as federal rules restrict PAPs for Medicare beneficiaries[3]. ## Step-by-Step Application Process 1. **Confirm Eligibility**: Visit viatris.com/pap or call 888-417-5780 (M-F, 8AM-5PM EST) to check if Symfi Lo is covered (it's under Viatris HIV products)[1][2]. 2. **Get Your Prescription**: Ask your doctor to prescribe Symfi Lo and complete the PAP application (they sign Section 1)[2][3]. 3. **Download and Fill Application**: Get the form from viatris.com/pap. Complete all sections: patient info, income proof, doctor's details, pharmacy info[2][5]. 4. **Gather Documents**: - Proof of income (W-2, 1040, pay stubs for 3 months). - Proof of residency (utility bill, lease). - Proof of no insurance (denial letter if applicable). - Pharmacy agreement (pharmacist signs)[2][3][5]. 5. **Submit**: Fax to 877-427-7290 or email ViatrisPAP@viatris.com. Include all signatures—**incomplete apps are rejected**[2][3]. 6. **Follow Up**: Call 888-417-5780 for status. Approval isn't guaranteed[2]. ## Timeline and Delivery Processing takes 2-4 weeks after receiving a complete application, though it varies. Once approved, medication ships to your pharmacy every 3 months (up to 84-100 days supply). Program lasts **12 months** with up to **11 refills** per enrollment. Your pharmacy dispenses free; no patient cost[2][3][5]. Reapply annually or as needed[2]. ## Alternatives if Denied - **Appeal**: Contact Viatris at 888-417-5780 with additional proof[1]. - **Other PAPs**: Check RxAssist.org or Needymeds.org for HIV generics[4]. - **HIV-Specific Aid**: AIDS Drug Assistance Programs (ADAP) in your state (hrsa.gov); patient assistance from Gilead (for tenofovir components) or generic options. - **Coupons/Savings Cards**: GoodRx or manufacturer copay cards if insured. - **Biosimilars/Generics**: No direct biosimilars listed; consider efavirenz/lamivudine/tenofovir generics from other makers[8]. ## Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Program details can change; always verify with Viatris (888-417-5780 or viatris.com/pap). Not medical advice—consult your healthcare provider. Viatris reserves the right to modify eligibility or end the program. Application doesn't guarantee approval[1][2][3]. (Word count: 1028)

Program information last verified: March 30, 2026

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