Strensiq

Indicated For

hypophosphatasia, HPP

About This Medication

# Alexion OneSource CoPay Program Patient Guide: How to Get STRENSIQ at Low or No Cost ## About STRENSIQ (Asfotase Alfa) STRENSIQ (asfotase alfa) is a prescription medication used to treat hypophosphatasia (HPP), a rare genetic disorder that affects bone and tooth development. The medication is administered as a self-injected subcutaneous injection. Because STRENSIQ is a specialty medication for a rare disease, it can be expensive. Alexion offers financial assistance programs to help eligible patients access this treatment. ## About the Alexion OneSource CoPay Program The **Alexion OneSource CoPay Program** is a manufacturer-sponsored patient assistance program designed to help eligible patients reduce their out-of-pocket costs for STRENSIQ treatment. This program is part of the broader OneSource support ecosystem, which also provides disease education, injection support, insurance navigation, and community connections at no cost to patients. ## Who Qualifies for Financial Assistance To be eligible for the Alexion OneSource CoPay Program, you must meet ALL of the following criteria: - Be enrolled in patient services through the Alexion OneSource program - Have commercial insurance coverage - Be prescribed STRENSIQ for an FDA-approved indication (perinatal/infantile-onset or juvenile-onset HPP) - Reside in the United States or its territories **Important Note:** If you have Medicare, Medicaid, or other federal- or state-funded insurance, you may not be eligible for the CoPay Program, but other assistance options may be available. Contact OneSource directly to discuss alternatives. ## Income Eligibility The search results do not specify explicit income thresholds or Federal Poverty Level (FPL) percentages for the Alexion OneSource CoPay Program. Income eligibility may be determined on a case-by-case basis or may not be a primary factor for patients with commercial insurance. Contact the program directly for specific income-related questions. ## Insurance Requirements Commercial insurance is required to qualify for the CoPay Program. The program is designed to help cover out-of-pocket costs such as copayments, coinsurance, and deductibles associated with your commercial health plan. If you have Medicare, Medicaid, or other government-funded insurance, you are not eligible for the CoPay Program. However, OneSource can provide information about alternative options for accessing treatment regardless of your insurance coverage. ## How to Apply: Step-by-Step ### Step 1: Get a Prescription from Your Healthcare Provider Your doctor must diagnose you with hypophosphatasia and prescribe STRENSIQ for an FDA-approved indication. Your healthcare provider will work with you and your insurance company to help you access STRENSIQ. ### Step 2: Enroll in Alexion OneSource You can enroll in the OneSource patient support program through one of three methods: - **Online:** Visit AlexionOneSource.com and complete the enrollment form - **Phone:** Call 1-888-765-4747 (Monday-Friday, 8:30 AM-8 PM ET) - **Mail/Fax:** Complete the OneSource PDF Enrollment Form and email it to OneSource@Alexion.com or fax to 1-800-420-5150 Enrollment can also be facilitated by PANTHERx Rare Pharmacy, the exclusive specialty pharmacy for STRENSIQ. ### Step 3: Complete Benefit Investigation Once your prescription is submitted, PANTHERx Rare Pharmacy will conduct a benefit investigation with your health plan to determine your coverage and out-of-pocket costs. ### Step 4: Prior Authorization Your health plan may require prior authorization before approving STRENSIQ. PANTHERx will handle this process and share the results with your healthcare provider. ### Step 5: Enroll in the CoPay Program Once you are enrolled in OneSource and have commercial insurance, you can enroll in the CoPay Program through the same enrollment methods listed in Step 2. OneSource will help you understand your estimated out-of-pocket costs and determine your eligibility for copay assistance. ## Required Documentation While specific documentation requirements are not detailed in available materials, typical requirements for enrollment may include: - Completed OneSource enrollment form with personal and insurance information - Proof of commercial insurance - Prescription from your healthcare provider - Consent to share health information with Alexion for program administration Contact OneSource at 1-888-765-4747 for a complete list of required documents. ## Application Processing Timeline The search results do not specify an exact processing timeline for CoPay Program applications. However, the overall STRENSIQ access process typically involves: - Benefit investigation by PANTHERx (timing varies by health plan) - Prior authorization review (timing varies by health plan) - Program enrollment and approval (contact OneSource for specifics) Reauthorization requirements depend on your specific healthcare plan. Contact PANTHERx or OneSource for details about your plan's reauthorization schedule. ## Medication Delivery STRENSIQ is dispensed and shipped by **PANTHERx Rare Pharmacy**, the exclusive preferred specialty pharmacy for STRENSIQ. PANHERx provides: - Coordination of your prescription with your insurance company - Shipments and ongoing refills - 24/7 availability and support - Clinical support services - An FDA-cleared sharps disposal container for use after injections Contact PANTHERx at strensiqrph@pantherxrare.com for questions about delivery and refills. ## What If Your Application Is Denied? If you are denied coverage or assistance, OneSource can help you explore alternative options: - Appeal your insurance company's decision with OneSource's support - Discuss alternative access programs or payment options - Connect with Alexion Field Reimbursement Managers (FRMs) for additional case-specific support Contact OneSource at 1-888-765-4747 to discuss next steps if your application is denied. ## Additional Support Through OneSource Beyond financial assistance, the Alexion OneSource program offers: - **Insurance Navigation:** Help understanding your coverage and estimated costs - **Disease Education:** Information about HPP and STRENSIQ treatment - **Injection Support:** Guidance on self-administering STRENSIQ injections - **Community Connections:** Peer Connects program to speak with others living with HPP - **Travel Support:** Help continuing your care while traveling - **Registry Participation:** Option to participate in the STRENSIQ registry to contribute to long-term safety data ## Important Disclaimer This guide provides general information about the Alexion OneSource CoPay Program based on available program materials. Program details, eligibility requirements, and benefits may change. This information is not a guarantee of coverage or assistance. For the most current and accurate information, contact Alexion OneSource directly at 1-888-765-4747 or visit AlexionOneSource.com. Always consult with your healthcare provider and insurance company regarding your specific situation and coverage options.

Program information last verified: March 30, 2026