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Cardiology

SAVAYSA

Generic: edoxaban

Manufacturer: Daiichi Sankyo  ·  Program: SAVAYSA Patient Assistance Program

Apply for assistance

Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Uninsured patients only

Residency

US resident

Program requires patients to be uninsured and unable to identify alternative payment sources

Program Information

Processing Time

2–4 weeks

Delivery Method

shipped to patient

Application Method

Online

Indicated for

Atrial fibrillation, deep vein thrombosis, pulmonary embolism, venous thromboembolism

About This Medication

SAVAYSA Patient Assistance Program Patient Guide: How to Get SAVAYSA (edoxaban) at Low or No Cost

SAVAYSA® (edoxaban) is a prescription medication used to help reduce the risk of stroke and dangerous blood clots in adults with non-valvular atrial fibrillation (AFib)—a heart rhythm disorder not caused by a heart valve problem—or for treating and preventing deep vein thrombosis (DVT) and pulmonary embolism (PE) after initial treatment.[2][5][6] The SAVAYSA Patient Assistance Program from Daiichi Sankyo offers this important medication at no cost to eligible uninsured patients who cannot afford it otherwise, helping ensure access to life-saving treatment when financial barriers stand in the way.[1][3][5]

Who Qualifies for the Program?

This program is designed specifically for patients facing significant financial hardship. To qualify, you must meet these key criteria:

  • Be prescribed SAVAYSA by a licensed healthcare provider.
  • Uninsured with no alternative payment sources—meaning no government insurance like Medicare or Medicaid, no private insurance, and no other means to pay for your medication.[1][3][5]
  • Demonstrate financial need, typically based on low income, though exact Federal Poverty Level (FPL) thresholds are not publicly specified. The program evaluates cases individually, focusing on uninsured patients unable to cover costs themselves.[1][3]

Important Note: This is not a copay assistance program. For insured patients, Daiichi Sankyo offers separate options like the SAVAYSA Savings Card, which can reduce out-of-pocket costs to as low as $4 per month for eligible commercially insured patients.[2][5] Medicare patients are generally not eligible for this free medication program.[1]

About SAVAYSA (edoxaban)

SAVAYSA is an oral, once-daily factor Xa inhibitor—a type of blood thinner (anticoagulant) that works by blocking a key protein in the clotting process to prevent harmful clots from forming.[5][9] Unlike older blood thinners like warfarin, SAVAYSA doesn't require routine blood tests or dietary restrictions, offering greater convenience.[5]

Key Uses

  • Reduce stroke risk in patients with non-valvular AFib (not caused by heart valve issues).[2][6][9]
  • Treat DVT and PE and prevent their recurrence after initial therapy.[9]

Dosage and Administration

SAVAYSA comes in 15 mg, 30 mg, or 60 mg tablets, taken once daily with or without food. Your doctor will determine the right dose based on your kidney function, weight, and other factors—kidney checks are essential before starting.[2] Always follow your doctor's instructions exactly, and never stop taking it without medical advice, as this increases clot risk.

Important Safety Information

SAVAYSA has a Boxed Warning for increased bleeding risk, including life-threatening bleeds. It's not for patients with mechanical heart valves or those on certain dialysis. Common side effects include bleeding. Discuss risks with your doctor, especially if you have kidney issues, are elderly, or take other blood thinners.[2]

Income Eligibility Breakdown

Specific income limits (like 400% of the Federal Poverty Level) are not detailed publicly for this program. Instead, eligibility hinges on being uninsured and proving you cannot identify alternative payment sources after a thorough review.[1][3][5] Daiichi Sankyo assesses applications case-by-case, considering household income, size, and expenses.

Here's a general guide based on similar programs (consult the application for your situation):

Household SizeEstimated Max Income (300-400% FPL)*Notes
1 (Individual)~$45,000-$60,000/yearUninsured only; proof of income required
2 (Couple)~$60,000-$80,000/yearHousehold income combined
3~$75,000-$100,000/yearIncludes dependents
4~$90,000-$120,000/yearLarger families may qualify higher

*Estimates for 2026; FPL varies by year/location. Actual thresholds not specified—apply to confirm.[1][3]

Insurance Requirements

Uninsured patients only. You must have no prescription coverage from:

  • Medicare (Part D), Medicaid, VA, Tricare, or other government programs.
  • Employer, marketplace, or individual private insurance.

If insured, explore SAVAYSA Support+™ savings card or copay assistance instead.[1][2][5] The program may require proof like a denial letter from insurers.

Step-by-Step Application Process

Applying is straightforward and done online via Daiichi Sankyo's AccessCentral4U portal. Here's how:

  1. Talk to your doctor: Confirm SAVAYSA is right for you and get a prescription. Ask them to complete the prescriber section (they can often submit electronically).
  2. Visit the website: Go to https://www.DSAccessCentral4U.com and select the Patient Assistance Program for SAVAYSA.[1][8]
  3. Create an account or start the application. Provide:
    • Personal info (name, address, DOB, SSN last 4 digits).
    • Household size and income proof (tax returns, pay stubs, etc.).
    • Proof of no insurance (benefits summary or denial letter).
  4. Upload documents digitally—no fax needed.[7]
  5. Submit and track status online. Call 1-866-4-DSI-NOW (1-866-437-4669) Mon-Fri 8AM-6PM ET for help.[8]

Your doctor may submit on your behalf via the same portal.

Timeline and Delivery

Processing time varies (typically 2-4 weeks), but expect medication shipped directly to your home at no cost if approved.[1][3] Refills ship automatically until eligibility ends (often 12 months). Track via the portal or hotline.[8]

Alternatives if Denied

  • SAVAYSA Savings Card: $4/month copay for insured patients.[2][5]
  • Partnership for Prescription Assistance (PPA): Free tool at pparx.org to find other programs.[1][10]
  • RxHope or RxAssist: Search databases for similar aid.[4][7]
  • State programs, NeedyMeds, or PAN Foundation for blood thinners.
  • Generic edoxaban (if available) or doctor-recommended switches like apixaban or rivaroxaban with their PAPs.

Contact AccessCentral4U for personalized guidance.[1]

Disclaimer

This guide is for informational purposes only and based on publicly available data as of 2026. Program details can change—always verify on DSAccessCentral4U.com or call 1-866-437-4669.[1][8] Not medical advice; consult your doctor for treatment decisions. Daiichi Sankyo reserves the right to modify eligibility. Assistance not guaranteed.

Program information last verified: March 30, 2026

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