Sarclisa

Indicated For

Multiple myeloma (relapsed/refractory)

About This Medication

# CareASSIST Patient Assistance Program Patient Guide: How to Get Sarclisa (isatuximab-irfc) at Low or No Cost Sarclisa (isatuximab-irfc) is a prescription medication used to treat adults with multiple myeloma who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor. The **CareASSIST Patient Assistance Program** from **Sanofi** helps eligible patients receive Sarclisa at no cost if they are uninsured, underinsured, or have Medicare Part B without supplemental coverage, and meet income guidelines.[1][5][7] ## About Sarclisa (isatuximab-irfc) Sarclisa is a targeted immunotherapy called a CD38-directed antibody that helps your immune system fight multiple myeloma cancer cells. It's given as an intravenous (IV) infusion by a healthcare professional, typically in combination with other drugs like pomalidomide and dexamethasone. Treatment usually starts with weekly doses for the first month, then every other week.[10] **Why is Sarclisa expensive without assistance?** As a biologic therapy, Sarclisa can cost tens of thousands of dollars per treatment cycle. Programs like CareASSIST bridge this gap for those who qualify, ensuring access to life-saving treatment.[1][2] ## Who Qualifies for CareASSIST Patient Assistance Program? This program is designed for patients facing financial barriers to Sarclisa. Key eligibility criteria include: - **Residency**: You must live in the United States, its territories, or possessions and be under the care of a U.S.-licensed healthcare provider.[5][7] - **Insurance status**: Uninsured, underinsured, or Medicare Part B patients with **no supplemental insurance** (like Medigap). Government programs like Medicaid may have separate options, but this PAP focuses on those without full coverage.[3][5][8] - **Income limits**: Your annual household income must not exceed the **greater of $100,000 or 500% of the federal poverty level (FPL)**.[5][7][9] - **Prescription**: Valid U.S. prescription for an approved indication from your doctor.[4] **Note**: A separate **CareASSIST Copay Program** exists for commercially insured patients, offering up to $25,000 annually in copay help (not for government insurance).[2][4] ## Income Eligibility Breakdown Income eligibility is based on household size and the greater of $100,000 or **500% FPL**. The FPL changes yearly; check current guidelines via the program or HHS.gov. Here's an example table using 2026 FPL estimates (always verify latest figures): | Household Size | 500% FPL (approx.) | Maximum Income (greater of this or $100k) | |----------------|---------------------|-------------------------------------------| | 1 | $75,300 | $100,000 | | 2 | $102,000 | $102,000 | | 3 | $128,600 | $128,600 | | 4 | $155,300 | $155,300 | | Add per person | +$26,700 | Varies | **How to calculate**: Add all household income (wages, benefits, etc.). Exclude certain deductions. Your Case Manager can help verify.[5][7] ## Insurance Requirements - **Uninsured or underinsured**: Ideal candidates—no insurance or coverage denied for Sarclisa.[3][8] - **Medicare Part B**: Eligible **only if no supplemental coverage** (Part D or Medigap). Medicare Part B covers infusions, but this program helps with medication costs if income-qualified.[5][8] - **Not eligible**: Full Medicaid, VA, TRICARE, or similar federal/state programs. Copay program excludes government insurance.[2][3] Your Case Manager will review your insurance details during enrollment.[1] ## Step-by-Step Application Process CareASSIST offers **multiple application methods** for convenience:[1][8] 1. **Visit the website**: Go to [sanoficareassist.com](https://www.sanoficareassist.com), select Sarclisa, and start online enrollment.[1] 2. **Call for help**: Dial **(833) 930-2273** (1-833-WE+CARE), Mon-Fri 9 AM-6 PM ET (or 8 PM per some sources). Spanish available.[1][5] 3. **Provider portal/fax/mail**: Your doctor completes sections; submit via fax (1-855-411-9689), mail (PO Box 220616, Charlotte, NC 28222), or portal.[8] **What to prepare**: - Proof of income (tax returns, pay stubs, etc.—exact docs confirmed by Case Manager). - Prescription from your doctor. - Insurance info (or proof of none). Once submitted, expect a **welcome call** if approved. Enrollment pairs you with a dedicated Case Manager for ongoing support.[2][8] ## Timeline and Delivery Processing time varies but aims to be prompt—patients notified via fax/mail, with a call for approvals. Medication is **shipped directly to you** (or your home) at no cost while eligible.[1][8] **Refills/reauthorization**: Likely required periodically; your Case Manager handles renewals, income recertification, and prescription updates. Stay in touch to avoid gaps.[4] ## Alternatives if Denied or Ineligible - **Copay Program**: If commercially insured ($0 copays up to $25k/year).[2] - **Other resources**: Case Manager connects to alternate funding, emotional/logistical support.[3] - **State programs**: Check PAN Foundation, HealthWell, or state AIDS Drug Assistance. - **Appeal**: Contact Case Manager to review denial reasons (e.g., income, residency). - **Generic/biosimilars**: None currently available for Sarclisa.[1] ## Important Disclaimer This guide is for informational purposes based on publicly available program details as of 2026. Eligibility, terms, and FPL change; **always verify directly with CareASSIST at (833) 930-2273 or sanoficareassist.com**. Not medical advice—consult your doctor. Program not valid where prohibited by law. Sanofi reserves rights to modify/amend.[1][5] **Word count: 950**

Program information last verified: March 30, 2026