Saphnelo

Indicated For

systemic lupus erythematosus

About This Medication

# AZ&Me Prescription Savings Program Patient Guide: How to Get Saphnelo (anifrolumab) at Low or No Cost Saphnelo (anifrolumab) is a prescription medication used to treat adults with moderate to severe systemic lupus erythematosus (SLE, or lupus) who are receiving standard therapy. The **AZ&Me Prescription Savings Program** from AstraZeneca helps eligible patients without insurance or underinsured patients access Saphnelo at low or no cost by providing it free for up to one year.[1] ## About Saphnelo (anifrolumab) **Saphnelo** is an intravenous infusion given every 4 weeks by a healthcare professional. It works by targeting a specific part of the immune system called **type I interferon receptor**, helping to reduce lupus disease activity, flares, and corticosteroid use. It's not a cure but can improve symptoms like joint pain, skin rashes, fatigue, and organ involvement when added to standard treatments like hydroxychloroquine or immunosuppressants. Always consult your doctor to see if it's right for you.[1] ## Who Qualifies for AZ&Me? The program is designed for **uninsured or underinsured U.S. residents** facing financial hardship. Key qualifications include: - **Household income** at or below specific limits based on family size (see table below). - **No prescription drug coverage** from private insurance, employer plans, VA/military benefits, Medicaid, Medicare Parts A/B/D, or state programs. - **U.S. residency** proof (Social Security number, green card, or work visa). - A valid prescription for Saphnelo from your doctor. Patients with **Medicare** may qualify if they lack Part D coverage or meet income criteria, but government insurance often excludes eligibility—call to confirm.[1] ## Income Eligibility Breakdown Eligibility is based on **annual household income** (before taxes). Limits are **400% of the Federal Poverty Level (FPL)** for many cases, adjusted by household size. Here's a clear table: | Household Size | Income Limit (Annual) | |----------------|-----------------------| | 1 (Individual) | $50,000 | | 2 (Couple) | $65,000 | | 3 | $80,000 | | 4 | $95,000 | | 5+ | Add ~$15,000 per person | *Notes: Limits may be higher in Alaska/Hawaii. Provide proof like tax returns (W-2/1099), Social Security statements. Income is evaluated case-by-case.[1] ## Insurance Requirements - **Uninsured**: Ideal candidates—no private or government drug coverage. - **Underinsured**: May qualify if insurance doesn't cover Saphnelo or has high costs, but no active coverage paying for it. - **Exclusions**: Medicare Part D, Medicaid, VA benefits, or any third-party payer. Medicare patients without Part D might be eligible—verify by phone.[1] ## Step-by-Step Application Process Applying is straightforward and free. Multiple methods available: 1. **Contact AZ&Me**: Call **(800) 292-6363** (Mon-Fri, 8 AM-6 PM ET) to speak with a representative, request an application, or apply over the phone.[1] 2. **Download Application**: Visit www.azandme.com (application URL may vary; call if needed).[1] 3. **Gather Documents**: - **Proof of income**: Last year's tax return, W-2/1099 forms, Social Security verification. - **Proof of residency**: Social Security #, green card, or work visa letter. - **Prescription**: New, valid script for Saphnelo from your doctor. - **Insurance info**: Proof of no coverage (e.g., denial letter) or details if underinsured.[1] 4. **Submit**: Mail to AZ&Me Prescription Savings Program, PO Box 898, Somerville, NJ 08876, or fax (800) 961-8323. Your doctor can also submit on your behalf.[1] 5. **Wait for Decision**: Processing takes **2-4 weeks**. You'll get an acceptance or denial letter.[1] ## Timeline and Delivery - **Approval**: 2-4 weeks after submission. Shipments start within 1-2 weeks of approval.[1] - **Enrollment**: Up to **12 months**. **Reauthorization** needed around month 10—your doctor or you can request refills by calling.[1] - **Delivery**: Free shipment to your **home** or **physician's office**. Refills are simple phone requests.[1] ## Alternatives if Denied If denied (e.g., income too high or insurance conflict): - **Reapply** if circumstances change (e.g., job loss). - **Other AstraZeneca Programs**: Check AZ&Me for insured patients or specific drugs. - **General Resources**: NeedyMeds, RxAssist.org, or PAN Foundation for lupus aid. - **Patient Access Network (PAN)**: Income-based copay help for underinsured. - **Manufacturer Copay Cards**: Ask your doctor about Saphnelo savings cards. - **State Programs**: Medicaid expansion or lupus-specific aid. No biosimilar alternatives for Saphnelo currently.[1] ## Important Disclaimer This guide is for informational purposes only and based on program details as of 2026. Eligibility, income limits, and rules can change—**always verify with AZ&Me at (800) 292-6363 or www.azandme.com**. Not medical advice; consult your healthcare provider before starting Saphnelo. AstraZeneca reserves the right to modify or end the program. Success not guaranteed; applications reviewed case-by-case. (Word count: 942)

Program information last verified: March 25, 2026