SANTYL

Indicated For

Dermal ulcers, debridement of necrotic tissue

About This Medication

# Smith+Nephew Patient Assistance Program (PAP) Patient Guide: How to Get SANTYL (Collagenase) at Low or No Cost SANTYL (Collagenase) Ointment is an FDA-approved prescription medicine used for enzymatic debridement of wounds, helping to remove dead tissue from dermal ulcers and severe burns to promote healing.[7] The **Smith+Nephew Patient Assistance Program (PAP)** provides eligible patients with **SANTYL at low or no cost** if they are uninsured or underinsured and meet specific financial and residency requirements.[1][4] ## About SANTYL (Collagenase) Ointment **SANTYL** is a topical ointment containing collagenase, an enzyme that selectively breaks down dead (necrotic) tissue in wounds without harming healthy tissue. It has been prescribed for over 50 years to treat conditions like pressure ulcers, diabetic foot ulcers, and severe burns.[7] **How it works:** Apply once daily to a thickness of about 2 mm (nickel-sized), after gently cleaning the wound with sterile saline. Cover with a dressing; moist wounds may need extra moisture like saline gauze.[7] Always follow your healthcare provider's instructions, as individual results vary. **Why it's important:** Removing dead tissue is a key step in wound healing, reducing infection risk and speeding recovery. Discuss with your doctor if SANTYL is right for your wound care needs.[7] ## Who Qualifies for the Program? The program is designed for patients facing financial hardship who cannot afford SANTYL. Key eligibility criteria include:[1][4] - **U.S. Residency:** Must be a permanent U.S. resident (including Puerto Rico) with proof.[1] - **Insurance Status:** Fully **uninsured** (no prescription coverage) or **underinsured** (insurance does not cover SANTYL). Medicare enrollees, government program participants, and skilled nursing home residents (Part A stay) are **not eligible**.[1][4] - **Financial Need:** Must meet income guidelines equivalent to financial requirements for Medicaid eligibility. Specific Federal Poverty Level (FPL) percentages or household size thresholds are not publicly detailed; eligibility is assessed individually based on your application.[1][4] - **Prescription:** Valid U.S. prescription for FDA-approved use by a licensed provider.[1] **Note:** Each application is reviewed individually. Applying does not guarantee approval.[1] ## Income Eligibility Breakdown Exact income thresholds (e.g., % of FPL) are not specified publicly; patients must qualify financially for Medicaid or show equivalent need. Contact the program for a personalized assessment. Here's a general overview based on similar programs:[1][4] | Household Size | Estimated Max Annual Income (300% FPL example)* | Notes | |---------------|-----------------------------------------------|-------| | 1 (Individual) | ~$45,000 | Must meet Medicaid financial criteria[1] | | 2 (Couple) | ~$61,000 | Varies by state; assessed per app[4] | | 3 | ~$77,000 | Proof of income required | | 4 | ~$93,000 | *Illustrative; call for exacts | *These are estimates for context (2026 FPL); program confirms via application. No fixed table provided by manufacturer.[1] ## Insurance Requirements - **Uninsured:** No prescription insurance at all.[1][4] - **Underinsured:** Have insurance, but it excludes SANTYL coverage.[1][4] - **Exclusions:** **Medicare (any part)**, Medicaid (unless product not covered and meets financials), government programs, or skilled nursing facilities.[1] **Separate Copay Program:** Insured patients paying >$20-$50 OOP may use Copay Card (up to $1000/year savings, 6 fills), but **not** for government insurance.[2][8] Download PAP form for low-income specifics.[3] ## Step-by-Step Application Process 1. **Get Prescribed:** Ask your U.S. licensed doctor for SANTYL and discuss PAP eligibility.[1][7] 2. **Download/Request Form:** Visit https://santyl.com/hcp/patient-assistance-program or call **(833) 965-1620**.[1] 3. **Complete Application:** Fill all sections: patient info, financial details, prescriber details. Both patient/representative and prescriber **must sign**.[1] 4. **Gather Documents:** - Completed, signed application[1] - Valid SANTYL prescription[1] - Proof of U.S. residency (e.g., ID, utility bill)[1] - Income proof if requested (for Medicaid-level assessment)[4] 5. **Submit:** Mail, fax, or email to PatientAssistanceProgram.us@PAP.smith-nephew.com. Ensure completeness![1] 6. **Wait for Review:** Program assesses eligibility; you'll be notified.[1] **Multiple methods** available; shipped directly to patient if approved.[1] ## Timeline and Delivery Processing time not specified; submit complete apps promptly. Medication ships free to your U.S. address. Follow up via phone if needed. Refills/reauthorization process not detailed—contact program for ongoing supply.[1] ## Alternatives if Denied - **Copay Assistance Card:** For commercially insured paying high OOP (not government plans).[2][8] - **Other PAPs:** Check rxassist.org or NeedyMeds for alternatives.[4] - **Discount Cards:** GoodRx or pharmacy discounts. - **Doctor/Pharmacy Help:** Ask prescriber for samples or hospital resources. - **State Programs:** Local Medicaid if eligible. - **No biosimilars** available for SANTYL.[1] ## Important Disclaimer This guide is for informational purposes only and based on available program details as of 2023-2026 sources. Eligibility, terms, and availability can change; always verify with Smith+Nephew at (833) 965-1620 or official site. Not medical advice—consult your healthcare provider for treatment. Smith+Nephew does not guarantee approval. Individual results vary.[1][7]

Program information last verified: March 30, 2026