Ryeqo
Generic: relugolix, estradiol, and norethindrone acetate
Manufacturer: Myovant Sciences · Program: Myovant Sciences Patient Assistance Program
Apply for AssistanceEligibility Criteria
Insurance Requirement
Uninsured or underinsured patients
Residency
US residency required
Program Information
Processing Time
2–4 weeks
Delivery Method
Varies by program
Application Method
Phone
Indicated For
Uterine fibroids, endometriosis
About This Medication
# Myovant Sciences Patient Assistance Program Patient Guide: How to Get Ryeqo at Low or No Cost Ryeqo (relugolix, estradiol, and norethindrone acetate) is a prescription medication used to treat certain conditions in women, such as uterine fibroids. The **Myovant Sciences Patient Assistance Program (PAP)** offers Ryeqo **at no cost** to eligible **uninsured or underinsured patients** who meet financial and residency criteria.[1][2][8] ## About Ryeqo Ryeqo combines **relugolix**, a GnRH receptor antagonist that reduces estrogen and progesterone production; **estradiol**, an estrogen to help prevent bone loss; and **norethindrone acetate**, a progestin for added hormonal balance. It is taken orally once daily and is indicated for women managing symptoms like heavy menstrual bleeding due to uterine fibroids. Always consult your healthcare provider to confirm if Ryeqo is right for you, as it may cause side effects such as hot flashes, hair loss, or mood changes.[1][2] ## Who Qualifies for the Program? The program targets patients with **financial need** who lack adequate insurance coverage for Ryeqo. Key eligibility includes: - **Residency**: Must live in the United States or U.S. Territories (including Puerto Rico).[1][2][8] - **Prescription**: Prescribed Ryeqo for an FDA-approved use by a licensed U.S. healthcare provider.[2] - **Insurance Status**: Uninsured, underinsured, or government-insured (e.g., Medicare, Medicaid) with unmet coverage for Ryeqo. Patients on Medicare Extra Help or Medicaid may need denial letters.[1][2][3][8] - **Income**: Must meet **income guidelines** verified through evaluation, potentially including credit profile checks via Experian Health (with patient consent).[1][3] **Government-insured patients** who qualify receive free medication for the full coverage year, and Myovant notifies their plans.[3][5][8] ## Income Eligibility Breakdown Specific income thresholds are not publicly detailed and require individual evaluation by the program. Factors like household size and total income are assessed. Patients consent to income verification, which may involve submitting proof or allowing a credit check.[1][3] | Household Size | Estimated Federal Poverty Level (FPL) Guideline* | Notes | |---------------|------------------------------------------------|-------| | 1 | Up to 400-500% FPL (e.g., ~$60,000-$75,000) | Exact limits vary; program evaluates case-by-case.[1][2] | | 2 | Up to 400-500% FPL (e.g., ~$80,000-$100,000) | Income from all sources counted.[3] | | 3+ | Scales with household size | Annual re-evaluation required.[5][8] | *Estimates based on typical PAP structures as of 2026; call program for precise thresholds. FPL updated yearly by HHS.[1][2][8] ## Insurance Requirements - **Uninsured**: Eligible if no pharmacy/medical coverage.[1] - **Underinsured**: Inadequate coverage for Ryeqo (e.g., high copays, denials).[2] - **Commercial Insurance**: May qualify if coverage is insufficient; program offers benefits investigation.[1][4] - **Medicare/Medicaid**: Eligible with proof of denial from Extra Help/Low-Income Subsidy or state program. Free product counts toward TrOOP for Part D.[3][5][8] Provide insurance cards or details on the enrollment form. Skip if uninsured.[1][3] ## Step-by-Step Application Process 1. **Get Prescribed**: Ask your doctor for Ryeqo and discuss the PAP. 2. **Download Form**: Obtain the **ORGOVYX Support Program Patient Start Form** (adapted for Ryeqo via Myovant PAP) from your provider or program site.[1][4] 3. **Complete Form**: Patient and prescriber fill pages 1-3: personal info, insurance details (or copies), consent for income/credit check, signatures required.[1][2][3] 4. **Select Services**: Check boxes for Benefits Investigation, Prior Authorization, or Appeal Assistance.[1] 5. **Submit**: **Fax to 1-844-826-8875**. Or e-prescribe to Mercalis Pharmacy for streamlined enrollment.[1][4][8] 6. **Program Contact**: Expect a call/text from 1-833-674-6899 (Mon-Fri, 8 AM-8 PM ET) for consent, enrollment confirmation, and shipment scheduling.[1][2] 7. **Verification**: Program performs benefits check, income evaluation.[1] **Patient consent** is mandatory for data sharing and verification.[3][7] ## Timeline and Delivery - **Processing**: Once faxed/e-prescribed, benefits investigation starts immediately. Approval timelines vary (typically 1-2 weeks), depending on documentation completeness.[1][8] - **Approval Notification**: Program calls to confirm eligibility and schedule shipment.[1][2] - **Delivery**: Ships free to your home or preferred pharmacy via specialty pharmacy (e.g., Mercalis). Remind patients of follow-up calls.[1][4] - **Refills**: Annual re-enrollment required; reverification of insurance/income during program.[5][8] ## Alternatives if Denied - **Appeal**: Request appeal assistance via the form or call 1-833-674-6899.[1] - **Bridge Program**: Short-term free supply (up to 2 months) while resolving access issues.[2][9] - **Other PAPs**: Check NeedyMeds, RxAssist, or Partnership for Prescription Assistance for Ryeqo alternatives.[3] - **Copay Cards**: Commercial patients may use support program copay assistance.[9] - **Generic/Low-Cost Options**: Discuss alternatives like other GnRH antagonists with your doctor. - **State Programs**: Apply for Medicaid Extra Help if eligible. ## Disclaimer This guide is for informational purposes based on available program details as of 2026. Eligibility, terms, and conditions can change; Myovant Sciences reserves the right to modify or end the program. Contact 1-833-674-6899 for latest info. Not affiliated with government programs. Consult your healthcare provider before starting Ryeqo. Free medication may affect taxes or insurance; report as required.
Program information last verified: March 30, 2026
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