Ruxience

Indicated For

Non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis

About This Medication

# Pfizer enCompass Patient Guide: How to Get RUXIENCE at Low or No Cost ## About This Program The **Pfizer enCompass Co-Pay Assistance Program** helps eligible patients afford RUXIENCE (rituximab-pvvr), a biologic medication used to treat certain blood cancers and autoimmune conditions. Pfizer offers multiple financial assistance pathways depending on your insurance status and income level. ## What is RUXIENCE? RUXIENCE is a rituximab biosimilar approved by the FDA to treat conditions including relapsed or refractory follicular or low-grade CD20-positive B-cell non-Hodgkin's lymphoma, previously untreated CD20-positive follicular B-cell NHL, rheumatoid arthritis, and other conditions as determined by your healthcare provider. As a biosimilar, it works similarly to the original biologic medication but may offer cost savings. ## Who Qualifies for Assistance? Eligibility varies depending on which Pfizer assistance program you apply for: ### Pfizer enCompass Co-Pay Assistance Program This program is designed for **commercially insured patients** and provides up to **$25,000 per calendar year** in copay assistance for RUXIENCE. You may be eligible if: - You have commercial health insurance (coverage through your employer, individual plan, or Federal Employer Plan) - You have been prescribed RUXIENCE for an FDA-approved indication - You are a U.S. resident or resident of an applicable U.S. territory - Your prescription was written by a licensed U.S. healthcare provider ### Pfizer Patient Assistance Program (PAP) This program provides **free RUXIENCE** to uninsured or government-insured patients who cannot afford their medication. You may be eligible if: - You are **uninsured or have government insurance only** (Medicare, Medicaid, CHAMPUS/TRICARE, or VA) - You cannot afford your copayment or prescription costs - Your annual household pre-tax income does not exceed **500-600% of the Federal Poverty Level** (FPL), depending on your household size - You have an FDA-approved diagnosis for RUXIENCE - You are a U.S. resident or resident of an applicable U.S. territory - You are treated in an outpatient setting **Important:** Commercially insured patients are not eligible for the free medicine program (PAP) but may qualify for the enCompass Co-Pay Assistance Program instead. ## Income Eligibility Breakdown For the Pfizer Patient Assistance Program, income limits are based on 500-600% of the Federal Poverty Level. Here are approximate 2026 income thresholds: | Household Size | 500% FPL (Approximate) | 600% FPL (Approximate) | |---|---|---| | 1 person | $68,750 | $82,500 | | 2 people | $92,500 | $111,000 | | 3 people | $116,250 | $139,500 | | 4 people | $140,000 | $168,000 | *Note: These are estimates based on 2026 federal poverty guidelines. Actual limits may vary. Contact Pfizer directly for current income thresholds specific to your household size.* ## Insurance Requirements **For Pfizer enCompass Co-Pay Assistance:** - You must have active commercial health insurance - Prior authorization from your insurance company may be required (Pfizer specialists handle this) - The program works alongside your existing insurance coverage **For Pfizer Patient Assistance Program (Free Medicine):** - You must be uninsured or have only government insurance (Medicare, Medicaid, CHAMPUS/TRICARE, VA) - Commercially insured patients are not eligible for this program - You may be required to explore other assistance options before applying ## Step-by-Step Application Process ### Step 1: Determine Which Program You Qualify For Contact Pfizer to confirm your eligibility: - **Pfizer enCompass (Co-Pay Assistance):** Call 1-844-722-6672, Monday-Friday, 8 AM-8 PM ET - **Pfizer Patient Assistance Program (Free Medicine):** Visit www.PfizerRxPathways.com or call 1-844-989-PATH (7284) ### Step 2: Gather Required Documents Prepare the following before applying: - Your prescription from your healthcare provider - Proof of income (W2 form, recent paycheck stub, or prior year tax return) - Proof of U.S. residency - Insurance information (if applicable) - Identification ### Step 3: Complete the Enrollment Form - For **enCompass Co-Pay Assistance:** Your healthcare provider can initiate enrollment by completing the Pfizer enCompass Enrollment Form - For **Patient Assistance Program:** You or your healthcare provider can apply through www.PfizerRxPathways.com or submit a completed enrollment form by mail or phone ### Step 4: Submit Your Application - Provide all required documentation - Attest to your inability to afford the medication - Confirm your FDA-approved diagnosis ### Step 5: Await Approval - Pfizer will review your application and contact you with a decision - Your healthcare provider may be contacted for additional information ## Timeline and Delivery **Processing Time:** - Prior authorization (if required): 24-72 hours - Overall application review: Typically 5-10 business days, though this may vary **Delivery Method:** - RUXIENCE is administered by infusion at a healthcare facility or hospital - Your healthcare provider's office will coordinate scheduling and administration - Copay assistance or free medication benefits are applied at the time of treatment ## What Happens If Your Application is Denied? If you are denied assistance: 1. **Request clarification** from Pfizer about the reason for denial 2. **Explore alternative programs:** You may qualify for a different Pfizer assistance program 3. **Contact patient advocacy organizations** that may provide additional financial support 4. **Speak with your healthcare provider** about generic alternatives or other treatment options 5. **Reapply** if your circumstances change (income, insurance status, etc.) ## Biosimilar Alternatives If RUXIENCE is not accessible, ask your healthcare provider about other rituximab biosimilars that may be available and covered by your insurance. ## Important Reminders - **Keep your information current:** Notify Pfizer immediately if your income, insurance, or contact information changes - **Reauthorization:** Some programs may require annual reauthorization or reapplication - **Work with your provider:** Your healthcare provider's office can help coordinate applications and prior authorizations - **No cost to apply:** There is never a fee to apply for Pfizer assistance programs ## Contact Information - **Pfizer enCompass Co-Pay Assistance:** 1-844-722-6672 (Monday-Friday, 8 AM-8 PM ET) - **Pfizer Patient Assistance Program:** 1-844-989-PATH (7284) or www.PfizerRxPathways.com - **Pfizer Oncology Together (General Support):** www.pfizeroncologytogether.com ## Disclaimer This guide provides general information about Pfizer's patient assistance programs as of March 2026. Program details, income limits, and eligibility requirements are subject to change at any time. For the most current and accurate information, contact Pfizer directly using the phone numbers and websites listed above. This guide is not a guarantee of eligibility or assistance. Always consult with your healthcare provider and Pfizer representatives to determine your specific eligibility and options.

Program information last verified: March 25, 2026