Rezzayo

Indicated For

candidemia, invasive candidiasis

About This Medication

# REZZAYO Patient Assistance Program Patient Guide: How to Get Rezzayo at Low or No Cost Rezzayo (rezafungin) is a once-weekly antifungal medication used to treat serious fungal infections like candidemia and invasive candidiasis in adults when other options are limited. The **REZZAYO Patient Assistance Program (PAP)** from Melinta Therapeutics helps **uninsured patients** who meet **household income requirements** get Rezzayo at low or no cost by providing free medication.[2][1] ## About Rezzayo and Why You Might Need It **Rezzayo** is an FDA-approved echinocandin antifungal injection for adults with **candidemia** (fungal infection in the bloodstream caused by Candida) or **invasive candidiasis** (when the fungus spreads to organs or tissues).[7][8] Unlike daily antifungals like caspofungin, Rezzayo is given **once weekly**, making treatment simpler, especially for those with limited alternative options.[7] It's typically administered in a hospital or outpatient setting, with a loading dose of 400 mg followed by 200 mg weekly.[1][8] Fungal infections like these can be life-threatening, particularly in hospitalized patients or those with weakened immune systems. If your doctor prescribes Rezzayo but cost is a barrier, the PAP can help by shipping medication directly to you or your doctor's office.[2] ## Who Qualifies for the REZZAYO PAP? This program is designed for patients facing financial hardship. Key eligibility criteria include: - **Age and residency**: Must be 18+ years old and a U.S. resident.[2] - **Insurance status**: Uninsured or without prescription drug coverage. **Not eligible** if enrolled in government programs like Medicare Part D, Medicaid, TRICARE, VA, or any state assistance programs.[2][4] - **Income**: Must demonstrate financial need based on household income (specific thresholds not publicly detailed; case-by-case review).[2] - **Prescription**: Valid prescription for an FDA-approved use from your healthcare provider.[2] - **Setting**: Both inpatients and outpatients may qualify.[2] **Note**: Patients in the Copay Savings Program (for commercial insurance) cannot enroll in PAP, and vice versa.[1][2][4] ## Income Eligibility Breakdown The program requires proof of household income but does not publish fixed Federal Poverty Level (FPL) percentages online. Eligibility is determined individually based on financial need for uninsured patients.[2] Contact Melinta or your provider for a personalized assessment. Here's a general guide to common PAP structures (consult program for Rezzayo specifics): | Household Size | Typical Max Income (e.g., 400-500% FPL)* | Notes | |----------------|------------------------------------------|-------| | 1 (Individual) | ~$60,000-$75,000/year | Proof required (tax returns, pay stubs) | | 2 (Couple) | ~$80,000-$100,000/year | Includes all household income | | 3 | ~$100,000-$125,000/year | Dependent children count | | 4+ | Add ~$20,000 per additional member | Case-by-case for larger families | *Estimates based on 2026 FPL; actual thresholds vary. Program may approve below these or require additional financial hardship proof.[2] ## Insurance Requirements - **Must be uninsured** for prescription drugs—no private coverage, Medicare Part D, Medicaid, etc.[2][4] - Government program enrollees are ineligible.[1][2] - If you have commercial insurance, consider the **Copay Savings Program** instead (up to $400/vial, no income limits).[1][2] - Disclose any assistance received to insurers, as required.[1] ## Step-by-Step Application Process 1. **Talk to your doctor**: They must complete the **Healthcare Provider Request Form** confirming your diagnosis and prescription need.[4] 2. **Gather documents**: - **Proof of income** (e.g., last 3 pay stubs, tax return, W-2, unemployment statement). - **Proof of residency** (e.g., utility bill, lease). - **Healthcare provider form** (download from rezzayo.com).[4] 3. **Submit application**: Use the **REZZAYO Hub Enrollment Form** (PDF available online). Options include fax, mail, or upload via hub services.[4] 4. **Call for help**: Contact REZZAYO Support Programs hotline (number on form or website) for assistance.[1] 5. **Wait for approval**: Melinta reviews eligibility; they may contact you for more info.[2] **Tip**: Start early—your provider can also get prior authorization support from the program.[1] ## Timeline and Delivery Processing time varies but aim for 1-2 weeks; urgent cases may be expedited. Once approved, Rezzayo is **shipped free** to your home or physician's office.[2][4] Treatment course is typically ≤6 vials (one course).[8] Track status via the support hotline.[1] ## Alternatives if Denied or Ineligible - **Copay Program**: For commercial insurance (up to $800 loading dose).[1][2] - **Other PAPs**: Check rxassist.org for Melinta or general programs.[3][9] - **Hospital assistance**: NTAP for Medicare inpatients (up to $4,387.50 add-on).[5] - **Generics**: Echinocandins like caspofungin, micafungin, anidulafungin (daily dosing).[8] - **State programs** or NeedyMeds.org for broader help. - **Appeal**: Resubmit with more docs or contact support.[1] ## Important Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Melinta Therapeutics determines eligibility, monitors use, and can change/discontinue the program anytime without notice. Not a guarantee of approval, coverage, or payment. Void where prohibited. Consult your doctor and the official form/website. See full Prescribing Information at rezzayo.com. Melinta assumes no liability for program services.[1][2][4] (Word count: 942)

Program information last verified: March 30, 2026