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Rezdiffra

Generic: resmetirom

Manufacturer: Madrigal Pharmaceuticals  ·  Program: Madrigal Patient Support - Patient Assistance Program

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Eligibility Criteria

Insurance Requirement

Uninsured or underinsured patients; not available for Medicare, Medicaid, or other federal/state healthcare program enrollees

Residency

US resident

Program Information

Processing Time

2–4 weeks

Delivery Method

shipped to patient

Application Method

Phone

Indicated For

NASH (nonalcoholic steatohepatitis), MASH (metabolic dysfunction-associated steatohepatitis), noncirrhotic fibrosis F2-F3

About This Medication

# Madrigal Patient Support - Patient Assistance Program: How to Get Rezdiffra at Low or No Cost ## About Rezdiffra (Resmetirom) Rezdiffra is a prescription medication used to treat certain liver conditions. If your doctor has prescribed Rezdiffra but you're concerned about the cost, the Madrigal Patient Support program may be able to help you access this medication at reduced or no cost. ## Who Qualifies for Assistance The Madrigal Patient Assistance Program is designed for patients who: - Are **uninsured or underinsured** and cannot afford their medication - Do not have coverage through Medicare, Medicaid, or other federal or state healthcare programs - Have been prescribed Rezdiffra by their healthcare provider - Are 18 years or older If you have private insurance, the program will first work with your insurance to determine your coverage. Financial assistance may be available if you have high out-of-pocket costs even with insurance coverage. ## Insurance Requirements and Eligibility The Madrigal Patient Assistance Program has specific eligibility requirements based on your insurance status: | Insurance Type | Eligible for PAP? | Next Steps | |---|---|---| | Uninsured | Yes | Apply directly to the program | | Underinsured (high out-of-pocket costs) | Yes | Program will verify coverage and assist with costs | | Private Insurance | Yes | Program works with insurance first; PAP available if needed | | Medicare | No | Not eligible for this program | | Medicaid | No | Not eligible for this program | | Other Federal/State Programs | No | Not eligible for this program | **Important:** If you are enrolled in Medicare, Medicaid, or other government healthcare programs, you are not eligible for the Madrigal Patient Assistance Program. Contact your insurance provider or your doctor for alternative assistance options. ## Income Eligibility The Madrigal Patient Support program does not publish specific income thresholds. Instead, the program evaluates each patient's financial situation individually. When you apply, a Case Manager will discuss your financial circumstances and determine what assistance options may be available to you. ## How to Apply: Step-by-Step ### Step 1: Enroll in Madrigal Patient Support Before applying for financial assistance, you must first enroll in the Madrigal Patient Support program. You can do this in two ways: **Option A: Enroll at Your Doctor's Office** - Ask your doctor's office to help you complete the Patient Authorization Form - Sign the form in person at your appointment - Your doctor's office will submit the form to Madrigal Patient Support **Option B: Enroll Online** - Visit MadrigalEnrollmentPatient.com - Complete the enrollment form electronically - You can also sign the eConsent form online if you prefer not to visit your doctor's office ### Step 2: Contact Madrigal Patient Support Once you've enrolled, call Madrigal Patient Support to discuss your financial situation and apply for the Patient Assistance Program: **Phone:** 1-877-219-7770 When you call, be prepared to discuss: - Your current insurance status - Your household income and financial situation - Any out-of-pocket costs you're facing - Your prescription details ### Step 3: Work with Your Case Manager After you enroll, a dedicated Case Manager will call you within a few days to: - Welcome you to the program - Explain your insurance coverage options - Discuss potential financial assistance options - Answer any questions you have - Help determine your eligibility for the Patient Assistance Program ### Step 4: Verify Insurance Coverage Madrigal Patient Support will work with your insurance company to understand your coverage. If you have insurance, they may need to: - Review your pharmacy benefits - Determine your copay or coinsurance amounts - Submit a prior authorization request to your insurance company if needed This process helps ensure you get the lowest possible cost for your medication. ### Step 5: Receive Your Medication Once your eligibility is confirmed and any insurance requirements are met, your medication will be shipped directly to you. Madrigal Patient Support will coordinate with a specialty pharmacy to ensure your Rezdiffra is delivered to your home. ## Timeline and Delivery **Processing Timeline:** While specific processing times are not published, the program aims to work quickly. Your Case Manager will call within a few days of enrollment to begin the process. Insurance verification and prior authorization (if needed) may take several additional days. **Delivery Method:** Your medication will be shipped directly to you by a specialty pharmacy. You'll receive a call when your medicine is ready for delivery. ## Refills When it's time to refill your prescription, Madrigal Patient Support or your specialty pharmacy will reach out to you. You don't need to reapply each time—the program will help coordinate your refills as long as you remain eligible. ## What If Your Application Is Denied? If you are not approved for the Patient Assistance Program, ask your Case Manager about: - Alternative financial assistance programs - Copay assistance options if you have insurance - Other resources that may help reduce your medication costs - Whether you can reapply if your financial situation changes ## Required Documents While specific documentation requirements are not detailed in the program materials, be prepared to provide: - Proof of your insurance status (insurance card or proof of being uninsured) - Your prescription from your doctor - Financial information to verify your eligibility - Any additional documents your Case Manager requests Your doctor's office or Case Manager will let you know exactly what documents you need to submit. ## Important Disclaimer This guide provides general information about the Madrigal Patient Support program. Program details, eligibility requirements, and assistance amounts may change. For the most current and complete information, contact Madrigal Patient Support directly at 1-877-219-7770 or visit MadrigalPatientSupport.com. This program is not insurance and does not replace your health insurance coverage. If you have questions about your specific situation, discuss them with your healthcare provider or Case Manager. ## Contact Information **Madrigal Patient Support** - **Phone:** 1-877-219-7770 - **Website:** MadrigalPatientSupport.com - **Online Enrollment:** MadrigalEnrollmentPatient.com - **Fax:** 1-844-411-1177 (for healthcare providers) --- *Last updated: March 2026. This information is based on publicly available program materials and may be subject to change.*

Program information last verified: March 30, 2026

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