Releuko

Indicated For

neutropenia

About This Medication

# Amneal PATHways Patient Support Program Patient Guide: How to Get Releuko (filgrastim-ayow) at Low or No Cost Releuko (filgrastim-ayow) is a biosimilar medication used to help reduce the risk of infection and neutropenia in patients undergoing certain cancer treatments like chemotherapy. The **Amneal PATHways Patient Support Program** helps eligible U.S. patients access Releuko through insurance navigation, financial assistance options like co-pay cards, and the Amneal Patient Assistance Program (PAP) for free medication when needed.[1][2][8][9] ## About Releuko (filgrastim-ayow) **Releuko** is an injectable biosimilar to Neupogen, containing filgrastim-ayow, a granulocyte colony-stimulating factor (G-CSF). It works by stimulating the bone marrow to produce more white blood cells, particularly neutrophils, which help fight infections. This is crucial for patients with chemotherapy-induced **febrile neutropenia** (low white blood cell count with fever) or those undergoing bone marrow transplants. Administered subcutaneously or intravenously, it's typically prescribed by oncologists for specific cycles of treatment.[1][2] Common side effects include bone pain, back pain, fatigue, nausea, and headache. Serious risks can include spleen rupture, acute respiratory distress syndrome (ARDS), or allergic reactions—always discuss with your doctor. Releuko offers a cost-effective alternative to reference biologics, and PATHways support makes it more accessible.[1] ## Who Qualifies for PATHways and Related Assistance? The **Amneal PATHways program** supports U.S. patients prescribed Releuko by providing comprehensive help, including enrollment specialists who explain benefits, check affordability options, and handle insurance issues. It's free and open to patients regardless of income for many services like prior authorization (PA) support, claims assistance, and appeals.[1][4][9] For deeper financial help: - **Co-pay Assistance Card**: Commercially insured patients may pay **$0 per treatment**. No income restrictions; limits and terms apply.[8][9] - **Patient Assistance Program (PAP)**: Free medication for up to **1 year** for uninsured, underinsured, or financially strained patients meeting criteria: U.S. resident (including Puerto Rico/US Virgin Islands), no affordable prescription coverage, and household income eligibility. Medicare Part D patients need proof of spending at least **3% of annual household income** on prescriptions.[2][3][4] **Income Eligibility Breakdown** Specific Federal Poverty Level (FPL) thresholds for PATHways PAP are not detailed in current forms, but programs like this typically use 400-500% FPL. Contact the program for your situation. Here's a general table based on standard PAP structures (confirm with Amneal):[3] | Household Size | Annual Income Limit (est. 400% FPL) | Notes | |---------------|-------------------------------------|-------| | 1 | $60,240 | Varies by program criteria | | 2 | $81,760 | Household income total | | 3 | $103,280 | Includes all sources | | 4 | $124,800 | Add ~$21,520 per additional | *Estimates for 2026; actuals based on program rules. Medicare spend proof required.[3] ## Insurance Requirements PATHways works with **all insurance types**: - **Commercial Insurance**: Get co-pay card for $0 out-of-pocket.[8][9] - **Medicare Part D**: Eligible for PAP if you've spent ≥3% of household income on meds (provide EOB or pharmacy printout).[3] - **Uninsured/Underinsured**: Direct PAP application for free meds.[2] Program specialists verify coverage, pursue PAs, track claims (received/in process/paid), and assist appeals if denied.[4] ## Step-by-Step Application Process 1. **Talk to Your Doctor**: Ask them to prescribe Releuko and complete PATHways enrollment (sections 5-10, including patient name/DOB, signature).[1] 2. **Complete Patient Sections**: Fill yellow sections (1-4): personal info, insurance cards (or scans of front/back), sign/date authorization.[1][3] 3. **Submit Enrollment** (multiple methods): - **Online Portal**: pathwaysenrollmentportal.com or pathwaysproviderportal.com (HCP login).[1][4][7] - **Fax**: 855-690-6573.[1][7] - **Phone**: (877) 764-9021 (PAP) or 866-426-6325 (PATHways), Mon-Fri 8AM-5PM CST / 8AM-8PM ET.[1][2][7] - **Mail**: For PAP, PO Box 220586 (check form).[3] 4. **Specialist Contacts You**: After enrollment, a Program Access Specialist (PAS) calls to confirm details, explain options, and start support.[1][4][9] 5. **For PAP**: Attach income proof, prescription, Medicare spend docs if applicable.[3] **Tip**: Blue HCP sections must be complete to avoid delays.[1] ## Timeline and Delivery - **Enrollment Processing**: Specialist contacts you soon after submission; no fixed time stated, but aim for quick HCP completion.[1] - **Approval**: Varies by insurance/PA; PAS tracks status.[4] - **Delivery**: Free meds shipped to doctor's office or pharmacy via PAP (up to 1 year supply).[2] Co-pay card activates at pharmacy. - **Refills**: PAS handles ongoing support; re-enroll yearly for PAP.[2][4] ## Alternatives if Denied or Ineligible - **Appeal Help**: PAS reviews denial reasons, provides templates, tracks appeals.[4] - **Other Biosimilars**: PATHways supports alternatives like Fylnetra or others if appropriate.[1] - **General Resources**: NeedyMeds.org, RxAssist.org, or manufacturer hubs. State programs or 340B clinics. - **Switch Programs**: If PAP ineligible, co-pay card or insurance appeals.[2][8] ## Important Disclaimer This guide is for informational purposes based on available program details as of 2026. Eligibility, terms, and benefits can change—**always verify with Amneal at (877) 764-9021 or PATHways site**. Not legal/medical advice. Consult your healthcare provider before starting Releuko. Program not available outside U.S. Amneal may discontinue anytime. Word count: 950.

Program information last verified: March 30, 2026