Regranex

Indicated For

diabetic neuropathic ulcers

About This Medication

# Smith+Nephew Patient Assistance Program Patient Guide: How to Get Regranex (becaplermin) at Low or No Cost Regranex (becaplermin) is a prescription gel used to treat diabetic foot ulcers by promoting healing through growth factors that stimulate cell growth in wounds.[1] The **Smith+Nephew Patient Assistance Program (PAP)** provides this medication at low or no cost to eligible uninsured or underinsured patients who meet specific financial and residency criteria, helping those facing financial hardship access essential wound care.[1][3] ## About Regranex (becaplermin) **Regranex** is a topical gel containing becaplermin, a recombinant human platelet-derived growth factor. It is FDA-approved specifically for treating non-infected, full-thickness diabetic foot ulcers that extend into the subcutaneous tissue or beyond, in patients with adequate blood supply to the ulcer area.[1] Applied directly to the wound once daily by a healthcare professional or under their guidance, it helps form granulation tissue, which is crucial for ulcer healing. Studies show it can increase the likelihood of complete wound closure compared to placebo. Common side effects include mild skin irritation, redness, or discoloration at the application site. Always use as prescribed, and consult your doctor for full details on risks, benefits, and proper use. This program focuses on Smith+Nephew products like Regranex for qualifying patients.[1][3] ## Who Qualifies for the Program? Eligibility is determined individually based on a completed application. Key requirements include:[1] - Permanent U.S. resident (including Puerto Rico). - Fully uninsured or confirmed underinsured (insurance must not cover the medication). - **Not enrolled in or eligible for Medicare**—this is a strict exclusion.[1] - Not in a skilled nursing facility under Part A Medicare. - Valid prescription from a licensed U.S. healthcare professional for an FDA-approved use. - Must meet financial requirements (income details assessed via application; specific thresholds not publicly detailed but require full financial disclosure).[1] Patients in hospitals, nursing homes, or with government coverage like Medicare do not qualify. Underinsured patients may apply if their insurance denies coverage for Regranex, but confirmation is needed.[1][2] ## Income Eligibility Breakdown The program requires completing a detailed financial information section on the application, but exact federal poverty level (FPL) percentages or household size thresholds are not specified publicly.[1] Eligibility is assessed case-by-case based on household income, assets, and hardships. Similar programs often use 300-400% FPL, but contact the program for your situation. | Household Size | Estimated Threshold Example (e.g., 300% FPL)* | Notes | |---------------|-----------------------------------------------|-------| | 1 (Individual) | ~$43,740 | Assessed individually; provide proof like tax returns. | | 2 (Couple) | ~$59,160 | Full financial details required. | | 3 | ~$74,580 | No fixed public tiers. | | 4 | ~$90,000 | Adjustments for larger families. | *Examples based on 2023 FPL; actual eligibility verified by program. No income? Submit a signed letter explaining.[1][10] Always submit complete financials for review. ## Insurance Requirements - **Medicare patients are ineligible**—no exceptions.[1] - Must be **fully uninsured** or **underinsured** (e.g., insurance denies coverage for Regranex). - Provide insurance details if applicable; program confirms lack of coverage. - No coverage from state plans or payers for the therapy is required for some Smith+Nephew programs.[2] - Commercial insurance denials may qualify if documented, but government programs like Medicare do not.[1][7] ## Step-by-Step Application Process 1. **Get a Prescription**: Ask your U.S.-licensed doctor for Regranex prescription for an FDA-approved use.[1][3] 2. **Download the Form**: Visit santyl.com/PAP or rxassist.org for the Smith+Nephew PAP application (interactive PDF).[3][4] 3. **Complete the Application**: Fill in patient details, financial info, prescriber section, and prescription. Both **patient (or representative)** and **prescriber must sign**.[1][3] 4. **Gather Documents**: Include proof of residency, income (e.g., tax returns, pay stubs), insurance denial letters if underinsured. Face sheet if from hospital.[1][2] 5. **Submit**: Fax to **833-965-1621** or email **PatientAssistanceProgram.us@PAP.smith-nephew.com**. Phone: **833-965-1620** (M-F, 8AM-5PM CST).[1][3] 6. **Follow Up**: Program notifies your doctor of approval, denial, or needed info.[3] Applications must be complete—missing info delays processing.[1] ## Timeline and Delivery Processing occurs upon receipt of complete application; similar programs approve in 1-2 business days, but expect 1-2 weeks.[2] Once approved, medication ships directly to you or your doctor. Duration is typically 1 year, with reauthorization possible.[2] Call 833-965-1620 for status. Delivery method not specified—confirm upon approval.[1] ## Alternatives if Denied - **Appeal**: Provide additional financial proof or insurance denial docs.[1] - **Other PAPs**: Check rxassist.org or needymeds.org for Regranex alternatives. - **Manufacturer Support**: Call Smith+Nephew Responds at 1-866-998-6798 for wound care help.[5] - **State Programs**: Medicaid (if eligible), 340B clinics, or community health centers. - **Copay Cards**: If commercially insured, ask doctor about savings offers. - **Generic Options**: No biosimilars listed; discuss with provider.[1] ## Important Disclaimer This guide is for informational purposes based on available program details as of latest data. Eligibility, rules, and availability can change; always verify with Smith+Nephew at 833-965-1620 or santyl.com/PAP.[1][3] Not medical advice—consult your healthcare provider. Program not for Medicare patients. Smith+Nephew reserves right to modify terms. Word count: 1028.

Program information last verified: March 30, 2026