Rebif

Indicated For

relapsing forms of multiple sclerosis, clinically isolated syndrome, relapsing-remitting disease, active secondary progressive disease

About This Medication

# MS LifeLines Patient Guide: How to Get Rebif at Low or No Cost ## About This Program MS LifeLines is EMD Serono's prescription assistance program designed to help patients with relapsing multiple sclerosis (RMS), clinically isolated syndrome (CIS), and active secondary progressive MS (SPMS) access Rebif (interferon beta-1a) at reduced or no cost. Whether you're uninsured, underinsured, or struggle with copayments, this program may help you afford this important medication. ## What is Rebif? Rebif is an interferon beta-1a medication used to treat multiple sclerosis. It works by modifying how your immune system responds to help reduce the frequency and severity of MS relapses. Interferon beta-1a is typically given by injection and is an important part of many MS treatment plans. Because MS is a chronic condition requiring long-term treatment, access to affordable medication is critical to your health. ## Who Can Qualify? MS LifeLines serves patients with the following conditions: - Relapsing Multiple Sclerosis (RMS) - Clinically Isolated Syndrome (CIS) - Active Secondary Progressive Multiple Sclerosis (SPMS) The program has two main eligibility pathways: **Free Medication Program**: For uninsured and underinsured patients who meet income requirements **Copay Assistance Program**: For commercially insured patients who need help paying copayments ## Income Eligibility While exact income thresholds vary by individual circumstances, MS LifeLines uses income guidelines to determine eligibility. The program considers household size and total household income. Below is a general reference table: | Household Size | Approximate Maximum Annual Income | |---|---| | 1 person | Varies by state/circumstance | | 2 people | Varies by state/circumstance | | 3 people | Varies by state/circumstance | | 4 people | Varies by state/circumstance | | 5 people | Varies by state/circumstance | | Each additional person | Add percentage per guidelines | **Important**: Income thresholds vary based on state of residence and individual circumstances. During your application call, a representative will discuss your specific situation and provide exact eligibility criteria. ## Insurance Requirements MS LifeLines serves patients with different insurance situations: - **Uninsured patients**: Eligible for free or low-cost medication - **Underinsured patients**: Eligible for free or reduced-cost medication - **Commercially insured patients**: Eligible for copay assistance to reduce out-of-pocket costs - **Medicare/Medicaid patients**: Contact the program directly to discuss your specific coverage situation ## What Documents You'll Need To apply, have the following information ready: 1. **Valid prescription** for Rebif from your neurologist or healthcare provider 2. **Income verification** (choose one): - Recent tax return (last 2 years) - Pay stubs from recent months - Social Security statements - Unemployment benefits statements - Other proof of household income 3. **Insurance information** (if applicable): - Insurance card or policy number - Name of insurance company 4. **Demographic information**: - Date of birth - Social Security number (for verification only) - Contact information - Household size and composition ## How to Apply: Step-by-Step Instructions ### Step 1: Gather Your Documents Collect your prescription and income verification documents before calling. Having these ready will speed up your application. ### Step 2: Call the Program Contact MS LifeLines at **1-877-447-3243** - **Available**: Monday-Friday during business hours - **What to expect**: A trained representative will answer your questions and guide you through the application - **Language assistance**: Ask about language services if English is not your primary language ### Step 3: Discuss Your Situation During the call, tell the representative about: - Your MS diagnosis and type (RMS, CIS, or SPMS) - Your current insurance status - Your household income and size - Any financial hardships affecting medication access - Your pharmacy preferences ### Step 4: Provide Required Information Share your income verification details and prescription information. The representative will explain what documents they need you to mail or fax. ### Step 5: Submit Documentation Send required documents as directed by the representative. Keep copies for your records. ### Step 6: Wait for Approval The program will review your application and contact you with a decision. ### Step 7: Receive Your Medication Once approved, Rebif will be delivered according to the program's procedures. You'll receive information about: - How medication will be delivered to you - Where to have prescriptions filled - Refill procedures - Contact information for questions during treatment ## Timeline and What to Expect **Processing Time**: Applications typically take **4-8 weeks** to process from the time all documents are received. **What affects processing speed**: - Completeness of your application - How quickly you return documentation - Verification of your information - Your insurance company's response time (if applicable) **Delivery**: Medication delivery varies depending on the program's processes and your location. Ask during your initial call about expected delivery timeframes. ## What Happens If You're Denied? If your application is denied, you have options: 1. **Ask why**: Request a specific explanation of what made you ineligible 2. **Reapply**: Circumstances change—if your situation improves later, you may become eligible 3. **Appeal**: Ask if the program allows appeals or reconsideration 4. **Alternative resources**: - Ask your neurologist about patient assistance - Contact state pharmaceutical assistance programs - Explore non-profit organizations that help MS patients - Visit NeedyMeds.org for additional resources - Contact the National Multiple Sclerosis Society for local support ## Reauthorization and Refills Once enrolled, ask the program representative about: - How long your assistance lasts - Whether you need to reauthorize annually - How to request refills - What to do if your circumstances change - Contact information for ongoing support ## Getting More Information **Program Website**: https://www.rebif.com - Additional program information - Frequently asked questions - Resources about Rebif and MS **Phone Support**: 1-877-447-3243 - Questions about eligibility - Application status updates - After-approval support **Your Healthcare Team**: - Your neurologist can provide a prescription - Your pharmacist can help with medication questions - Nurse hotlines can answer clinical questions about Rebif ## Important Legal Information This guide provides general information about MS LifeLines. Program eligibility, requirements, and benefits may change. Always verify current information directly with the program before applying. This guide does not guarantee eligibility or approval. Each application is reviewed individually based on current program guidelines and the applicant's specific circumstances. MS LifeLines is a legitimate manufacturer assistance program operated by EMD Serono. Never pay upfront fees to apply—legitimate assistance programs are free. ## Your Next Step If you have MS and struggle to afford Rebif, contact MS LifeLines today at **1-877-447-3243**. A representative can answer your specific questions and help determine if you qualify for assistance. Getting connected to affordable medication is an important step in your MS management plan.

Program information last verified: March 25, 2026