RAVICTI

Indicated For

Urea Cycle Disorders

About This Medication

# Amgen By Your Side Patient Guide: How to Get RAVICTI at Low or No Cost RAVICTI (glycerol phenylbutyrate) is a prescription medication used to treat urea cycle disorders (UCDs) in adults and children ages 2 years and older. The **Amgen By Your Side** program, offered by **Amgen**, provides financial assistance to help eligible patients access RAVICTI at low or no cost, including copay support and patient assistance options.[2][4] ## About RAVICTI **RAVICTI** is an oral liquid medication that helps manage **urea cycle disorders (UCDs)**, rare genetic conditions where the body cannot properly remove ammonia from the blood. High ammonia levels can cause brain damage, developmental delays, or even death if untreated. RAVICTI works by providing glycerol phenylbutyrate, which is broken down in the intestines into phenylbutyrate and then into phenylacetate. These compounds bind to ammonia, forming phenylacetylglutamine, which is excreted in urine, safely removing excess ammonia.[2] UCDs affect about 1 in 35,000 births, with types including ornithine transcarbamylase (OTC) deficiency, carbamoyl phosphate synthetase (CPS) deficiency, and others. Patients often need lifelong treatment with nitrogen-scavenging drugs like RAVICTI, alongside dietary restrictions low in protein. Common side effects include headache, nausea, vomiting, and fatigue. Always consult your doctor for personalized advice on using RAVICTI.[2] RAVICTI is expensive, often costing tens of thousands per month without assistance, making programs like Amgen By Your Side essential for many families.[4] ## Who Qualifies for Amgen By Your Side? The program has **two main tracks**: a **Copay Assistance Program** for insured patients and a **Patient Assistance Program** for uninsured or underinsured patients with financial need.[1][3] - **Copay Program**: For commercially insured patients 18+ years old, U.S. residents (including Puerto Rico). No income requirements (needs-based: no). Helps reduce out-of-pocket copays, potentially to $0.[1] - **Patient Assistance Program**: For uninsured or those with limited coverage. Needs-based (yes), with eligibility determined **case-by-case** based on **Federal Poverty Level (FPL)** income guidelines. U.S. residents only; enrollment required.[2][3] **Key Requirements**: - Valid U.S. prescription for RAVICTI. - 18+ years old for copay program; all ages may qualify for patient assistance (confirm via phone).[1][3] - No coverage required for patient assistance.[3] ## Income Eligibility Breakdown Income eligibility varies by program track. The copay program has **no income limits**. Patient assistance uses **FPL-based thresholds**, evaluated case-by-case (exact % of FPL not specified; typically 400-500% for similar programs, but call to confirm).[2] | Household Size | Estimated Max Income (400% FPL example)* | Notes | |---------------|-----------------------------------------|-------| | Individual | $60,240 | Case-by-case; FPL-based[2] | | Couple | $81,760 | Contact program for exacts[2] | | Family of 3 | $103,280 | Medicare Part D may qualify[2] | | Family of 4 | $124,800 | Higher for larger families | *Example based on 2026 FPL estimates; actual thresholds determined case-by-case. Program reviews full financial picture.[2] ## Insurance Requirements - **Commercial Insurance**: Eligible for copay help (potentially $0 copay). Medicare Part D patients **may qualify**—contact program.[2][1] - **Uninsured/No Coverage**: Patient assistance available if income-eligible.[3] - **Government Insurance** (Medicaid, etc.): Likely ineligible for copay; check patient assistance.[2] Amgen By Your Side pairs you with a **Patient Access Liaison (PAL)** or **Clinical Nurse Educator (CNE)** to navigate insurance, prior authorizations, and appeals.[4] ## Step-by-Step Application Process Applications are **phone-based**—simple and personalized.[2] 1. **Verify Eligibility**: Discuss with your doctor if RAVICTI is right. Confirm insurance status. 2. **Call Amgen By Your Side**: Dial **(855) 823-7878** (Mon-Fri, typical business hours). Have ready: prescription details, insurance info, household income, ID.[2][4] 3. **Enroll**: Speak to a representative. They'll assign a PAL/CNE for support.[4] 4. **Submit Documents**: Program may request proof of income (tax returns, pay stubs), insurance denial (if applicable), prescription.[2] 5. **Approval**: Case-by-case; expect quick review.[2] 6. **Receive Medication**: Shipped to pharmacy or home (details provided post-approval).[4] Your PAL helps with benefits investigation, prior authorizations, and appeals.[4] ## Timeline and Delivery - **Processing**: Varies; copay cards issued quickly (days). Patient assistance case-by-case (1-2 weeks typical for similar programs).[1][2] - **Delivery**: Medication sent to your pharmacy or via mail/specialty pharmacy. PAL coordinates.[4] - **Refills**: Automatic for approved duration; reauthorization may apply.[4] ## Alternatives if Denied or Ineligible - **Appeal**: Work with PAL for insurance appeals or program reconsideration.[4] - **Biosimilar/Generic**: **Generic glycerol phenylbutyrate** available—lower cost option.[2] - **Other Programs**: PAN Foundation, HealthWell Foundation (UCD-specific grants). State assistance or 340B pharmacies.[2] - **Manufacturer Samples**: Doctor may provide starter doses. - **Patient Advocacy**: Contact UCD groups like National Urea Cycle Disorders Foundation for resources. ## Important Disclaimer This guide is for informational purposes only and based on available program details as of 2026. Eligibility, terms, and benefits can change—**always verify directly with Amgen By Your Side at (855) 823-7878**.[2][4] Not affiliated with Amgen. Consult your healthcare provider before starting/stopping RAVICTI. Assistance not guaranteed; individual results vary. Report side effects to FDA at 1-800-FDA-1088.[2]

Program information last verified: March 25, 2026