PYRUKYND

Indicated For

pyruvate kinase (PK) deficiency

About This Medication

# PYRUKYND Patient Assistance Program Guide: Getting Mitapivat at Low Cost ## What is the PYRUKYND Patient Assistance Program? The PYRUKYND Patient Assistance Program (PAP) is designed to help patients with pyruvate kinase (PK) deficiency access mitapivat at reduced or no cost. If you're struggling to afford this medication, this program may be able to help you get the treatment you need. ## Who is Eligible? You may qualify for the PYRUKYND PAP if you meet these criteria: - You have a valid prescription for PYRUKYND (mitapivat) from your doctor - You are a U.S. resident - You are uninsured or underinsured (your insurance doesn't adequately cover the medication) - Your household income falls within the program's guidelines - You do not have government insurance coverage (Medicare, Medicaid, VA, or other government programs do not qualify for this assistance program) ## Income Guidelines Income limits vary based on your household size and situation. The program uses a sliding scale approach, meaning your cost assistance may depend on your specific income level. During the application process, you'll provide income information, and Agios will determine your eligibility and assistance level. For the most current income thresholds, contact the program directly at **(877) 772-4467**. The support team can provide specific numbers based on your household size. ## Insurance Requirements This program is specifically for: - **Uninsured patients** - Those with no health insurance coverage - **Underinsured patients** - Those whose insurance doesn't adequately cover PYRUKYND **Important**: If you have government insurance (Medicare, Medicaid, Veterans Affairs, Tricare, or other state/federal programs), you are not eligible for this PAP. However, you may have other assistance options available through your government program. ## How to Apply: 4-Step Process **Step 1: Call the Support Line** Contact Agios at **(877) 772-4467** to request an application or begin the application process over the phone. The support team can guide you through eligibility questions. **Step 2: Gather Required Documents** Prepare the following: - Proof of income (recent tax returns, pay stubs, or other income documentation) - A valid prescription for PYRUKYND from your healthcare provider - Proof of U.S. residency **Step 3: Submit Your Application** Complete the application by phone with a representative, or request that an application be mailed to you. Provide your income documentation and prescription information as directed. **Step 4: Receive Approval and Assistance** Once approved, you'll receive information about your co-pay assistance level or free medication eligibility. Your medication can be shipped directly to you or your pharmacy. ## Timeline for Approval Applications are typically reviewed and approved quickly. Most patients receive a decision within 1-2 weeks of submitting a complete application. The exact timeline may vary based on how quickly you provide all required documents. ## Savings Card Option The PYRUKYND program also offers a **savings card** for eligible patients. This card can help reduce your out-of-pocket costs if you have insurance. Ask about this option when you call, as it may provide additional savings depending on your coverage. ## Do You Need Reauthorization? No. Once you're approved for the PYRUKYND PAP, you will **not** need to reapply or reauthorize your assistance. Your coverage continues as long as you remain eligible. ## What About Refills? Once your initial approval is in place, refills are handled automatically through the program. You won't need to reapply for each refill. ## For More Information **Phone Support**: (877) 772-4467 **Online Resources**: https://www.pyrukynd.com/hcp/resources-and-support/myagios-support/ The support team can answer specific questions about your situation, help you understand income guidelines, and guide you through the entire application process. ## Next Steps If you have PK deficiency and are prescribed PYRUKYND, don't delay due to cost concerns. Call the PAP line today to learn if you qualify. The process is straightforward, and the support team is ready to help you access this important medication.

Program information last verified: March 25, 2026