Pulmozyme

Genentech Patient Foundation Patient Guide: How to Get Pulmozyme (dornase alfa) at Low or No Cost

Pulmozyme (dornase alfa) is a prescription inhaled medication used to thin mucus in the lungs of people with cystic fibrosis (CF), helping to improve breathing and reduce lung infections. The Genentech Patient Foundation offers this medicine at no cost to eligible patients based on financial need and insurance status, providing up to one year of free medication with ongoing access as long as you qualify—no re-enrollment needed.[1][2][4][8]

About Pulmozyme and Why Assistance Matters

Pulmozyme (dornase alfa) is a recombinant human deoxyribonuclease (rhDNase) enzyme nebulized daily to break down thick, sticky mucus in CF lungs. This reduces exacerbations, improves lung function, and enhances quality of life, but its high list price—often over $3,000 per month—makes it unaffordable for many without help.[1][4] The Genentech Patient Foundation bridges this gap for uninsured, underinsured, or financially burdened patients, ensuring consistent access without upfront costs.[2][8]

Who Qualifies?

Eligibility focuses on U.S. residents (including Puerto Rico) treated by a U.S.-licensed physician, with no citizenship check required. You may qualify if you fall into one of three main groups:[4][9]

• Uninsured patients with household income under $150,000 (exact thresholds vary by household size; use their online tool or call to confirm).[4]
• Insured patients whose plan covers Pulmozyme but has an out-of-pocket maximum >7.5% of yearly income, or who can't afford cost-sharing.[1][4]
• Underinsured (no coverage for Pulmozyme) meeting financial criteria.[2][9]

Not eligible: Government programs like Medicare/Medicaid that fully reimburse (exceptions rare), or if your insurer requires/ hides coverage to force PAP use.[4][6]

Income Eligibility Breakdown

Specific Federal Poverty Level (FPL) percentages aren't publicly fixed but tie to income under $150,000 for uninsured, adjusted for household size. Insured criteria emphasize out-of-pocket burdens >7.5% income. Confirm exacts via (888) 941-3331 or their qualifier tool.[4][9]

Pro tip: Provide household size, income, AGI, deductible/OOP details on forms for quick assessment.[6][7]

Insurance Requirements

• Uninsured: Primary group; easiest if income-qualified.[2]
• Commercially insured: OK if OOP too high or coverage gaps exist.[4][8]
• Medicare/Medicaid: Generally ineligible if reimbursed; underinsured parts may qualify.[8]
• Pursue other help first if insured—Foundation is last resort.[1][5]

No proof of denial/appeal needed; apply anytime.[5]

Step-by-Step Application Process

Applications are multiple methods; both Patient Consent Form and Prescriber Foundation Form required—submit together.[1][4]

1. Prepare docs: Gather proof of income (taxes, paystubs), insurance info (card/ID), household size.[1][6]
2. Complete Patient Consent Form (English/Spanish): Online at gene.com/patients/enrollment. Include income, household, insurance details. Sign/date.[1][6]
3. Doctor completes Prescriber Foundation Form: Details diagnosis (CF), Pulmozyme dose. Download from GenentechPatientFoundation.com.[4]
4. Submit:
   • Online: eSubmit/My Patient Solutions (fastest).[1][3]
   • Text photo: 650-877-1111.[1]
   • Fax: 833-999-4363.[1][2]
   • Phone help: (888) 941-3331 (Mon-Fri 6am-5pm PT).[2]
5. Wait: Processed in 5 business days; office contacted with outcome.[1][7]

Both forms mandatory—no action without them.[1][4]

Timeline and Delivery

• Processing: 5 business days after complete submission.[1]
• Notification: Patient & doctor called with results/next steps.[1][7]
• Delivery: Free Pulmozyme shipped to your home or doctor's office; one year supply, auto-refills if eligible—no re-enrollment.[1][8]
• Ongoing: Continues while qualified; reauthorization may check status annually.[8]

Alternatives if Denied

• Call Foundation Specialist (888) 941-3331 for reasons/options.[2]
• Appeal insurer for coverage (no proof needed for PAP).[5]
• Other PAPs: Check NeedyMeds, RxAssist for CF programs.
• State assistance, CF Foundation grants, or Genentech co-pay help if commercially insured.[2][6]
• Generic/biosimilars: None currently.[8]

Important Disclaimer

This guide summarizes Genentech Patient Foundation for Pulmozyme based on available info as of 2026; eligibility/rules change—always verify with (888) 941-3331 or gene.com/patients/patient-foundation. Not medical/financial advice; consult doctor/ advisor. Genentech denies if fraud suspected. Program US-only.[1][4][8]